Zobrazeno 1 - 10
of 50
pro vyhledávání: '"John J McCabe"'
Publikováno v:
Frontiers in Stroke, Vol 2 (2023)
Recurrent vascular events after stroke are common despite contemporary therapies and there is an unmet clinical need for improved secondary prevention. Inflammation is a probable causal factor in first and recurrent stroke and is a promising therapeu
Externí odkaz:
https://doaj.org/article/77a6610cd87c4d34af1a62d07cce1934
Autor:
John J. McCabe, Nicholas R. Evans, Sarah Gorey, Shiv Bhakta, James H. F. Rudd, Peter J. Kelly
Publikováno v:
Cells, Vol 12, Iss 16, p 2073 (2023)
Atherosclerosis is a chronic systemic inflammatory condition of the vasculature and a leading cause of stroke. Luminal stenosis severity is an important factor in determining vascular risk. Conventional imaging modalities, such as angiography or dupl
Externí odkaz:
https://doaj.org/article/020e4b0dfbdb46c9b828d85b59b4b779
Autor:
Rahul Herlekar, Akangsha Sur Roy, Saur Hajiev, Isuru Induruwa, Smriti Agarwal, Nicholas R Evans, Kayvan Khadjooi, Hugh Markus, Eoin O’Brien, Elizabeth Warburton, George Zachariah, John J McCabe
Publikováno v:
European Stroke Journal. 8:541-548
Background: For reasons poorly understood, strokes frequently occur in patients with atrial fibrillation (AF) despite oral anticoagulation. Better data are needed to inform randomised trials (RCTs) of new strategies to prevent recurrence in these pat
Autor:
John J. McCabe, Cathal Walsh, Sarah Gorey, Katie Harris, Pablo Hervella, Ramon Iglesias-Rey, Christina Jern, Linxin Li, Nobukazu Miyamoto, Joan Montaner, Annie Pedersen, Francisco Purroy, Peter M. Rothwell, Catherine Sudlow, Yuji Ueno, Mikel Vicente-Pascual, William Whiteley, Mark Woodward, Peter J. Kelly
Publikováno v:
McCabe, J J, Walsh, C, Gorey, S, Harris, K, Hervella, P, Iglesias-Rey, R, Jern, C, Li, L, Miyamoto, N, Montaner, J, Pedersen, A, Purroy, F, Rothwell, P M, Sudlow, C, Ueno, Y, Vicente-Pascual, M, Whiteley, W, Woodward, M & Kelly, P J 2023, ' C-Reactive Protein, Interleukin-6, and Vascular Recurrence After Stroke : An Individual Participant Data Meta-Analysis ', Stroke . https://doi.org/10.1161/STROKEAHA.122.040529
Background: Anti-inflammatory therapies reduce recurrent vascular events in coronary disease. Existing studies have reported highly conflicting findings for the association of blood inflammatory markers with vascular recurrence after stroke leading t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e2c9fd3ba4017cd45cd7c6a6fcd181
https://www.pure.ed.ac.uk/ws/files/343425111/Final_Mansucript_BISC_for_Publication_clean.docx
https://www.pure.ed.ac.uk/ws/files/343425111/Final_Mansucript_BISC_for_Publication_clean.docx
Autor:
Ronan Collins, Joseph Harbison, Tim Cassidy, L Healy, Sean M. Murphy, Peter J. Kelly, Bradford B. Worrall, Martin O'Donnell, R Mulcahy, E O’Reilly, Sarah Coveney, F Hsu, Barry Moynihan, John J McCabe, J McManus
Publikováno v:
Age and Ageing. 50:ii1-ii4
Background Recent randomised trials showed benefit for anti-inflammatory therapies in coronary disease but excluded stroke. The prognostic value of blood inflammatory markers after stroke is uncertain and guidelines do not recommend their routine mea
Autor:
Elizabeth Callaly, David Connellan, John S. Lambert, Lorraine Kyne, Walter Cullen, Aoife G. Cotter, Gerard Sheehan, K. Diffley, John J McCabe, Karen Ryan, Tara McGinty
Publikováno v:
Age and Ageing
Introduction The COVID-19 pandemic has brought the decision-making process regarding cardiopulmonary resuscitation into focus. This study aims to analyse Do-Not-Attempt CPR (DNACPR) documentation in older hospitalised patients before and during the C
Autor:
Sarah Coveney, John J McCabe, Sean Murphy, Aine Merwick, Eamon Dolan, Gillian Horgan, Peter J. Kelly, M. de Gaetano, David Williams, Morgan Crowe, Michael Marnane, Joseph Harbison, Imelda Noone, Orina Belton, Tim Cassidy
Publikováno v:
International Journal of Stroke. 17:163-171
Background Inflammation driven by pro-inflammatory cytokines is a new therapeutic target in coronary disease. Few data exist on the association of key upstream cytokines and post-stroke recurrence. In a prospective cohort study, we investigated the a
Autor:
John S. Lambert, John J McCabe, Lorraine Kyne, Gerard Sheehan, David Connellan, Tara McGinty, Kara Diffley, Elizabeth Callaly, Karen Ryan, Walter Cullen, Aoife G. Cotter
Publikováno v:
Age and Ageing
Introduction the COVID-19 pandemic has brought the decision-making process regarding cardiopulmonary resuscitation (CPR) into focus. The aim of this study is to compare rates of Do-Not-Attempt-CPR (DNACPR) documentation in older hospitalised patients
Autor:
John J McCabe, Peter J. Kelly, Eimear O'Reilly, Eamon Dolan, Simon Cronin, David Williams, Ronan Collins, Tim Cassidy, George Pope, Sarah Coveney, Joseph Harbison, Sean M. Murphy, Margaret O'Connor
Publikováno v:
Age and Ageing. 48:iii1-iii16
Background Inflammation is thought to play an important role in atherosclerotic stroke mechanisms. There is growing interest in the prognostic role of inflammatory biomarkers as risk factors for recurrent vascular events, after ischaemic stroke or tr
Publikováno v:
Age and Ageing. 48:iii17-iii65
Background Acute stroke and its aftermath is the commonest cause of acquired disability amongst community dwelling adults. Analysis of hospital discharge rates over time and the influence of patient age is important and may offer important insights o