Zobrazeno 1 - 10 of 66 pro vyhledávání: '"John J Connell"'
1
Akademický článek
Precision medicine for liver tumours with quantitative MRI and whole genome sequencing (Precision1 trial): study protocol for observational cohort study
Autor: Matt Kelly, Rajarshi Banerjee, Myrddin Rees, Fenella K Welsh, John J Connell, Sarah Gooding
Publikováno v: BMJ Open, Vol 12, Iss 4 (2022)
Introduction Radiogenomic analysis of patients being considered for liver resection is seldom performed in the clinic despite recent evidence indicating that quantitative MRI could improve posthepatectomy outcomes. Meanwhile, the increasingly accessi
Externí odkaz: https://doaj.org/article/d97f69232135464ea04f6b02110b6eeb
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2
Akademický článek
Quantitative magnetic resonance imaging predicts individual future liver performance after liver resection for cancer.
Autor: Damian J Mole, Jonathan A Fallowfield, Ahmed E Sherif, Timothy Kendall, Scott Semple, Matt Kelly, Gerard Ridgway, John J Connell, John McGonigle, Rajarshi Banerjee, J Michael Brady, Xiaozhong Zheng, Michael Hughes, Lucile Neyton, Joanne McClintock, Garry Tucker, Hilary Nailon, Dilip Patel, Anthony Wackett, Michelle Steven, Fenella Welsh, Myrddin Rees, HepaT1ca Study Group
Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0238568 (2020)
The risk of poor post-operative outcome and the benefits of surgical resection as a curative therapy require careful assessment by the clinical care team for patients with primary and secondary liver cancer. Advances in surgical techniques have impro
Externí odkaz: https://doaj.org/article/efe9d90ff055482e9e64951c38de830b
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3
Akademický článek
Scalable magnet geometries enhance tumour targeting of magnetic nano-carriers
Autor: Matin Mohseni, John J. Connell, Christopher Payne, P. Stephen Patrick, Rebecca Baker, Yichao Yu, Bernard Siow, May Zaw-Thin, Tammy L. Kalber, Quentin A. Pankhurst, Mark F. Lythgoe
Publikováno v: Materials & Design, Vol 191, Iss , Pp - (2020)
Targeted drug delivery systems aim to increase therapeutic effect within the target tissue or organ, while reducing off-target toxicity associated with systemic delivery. Magnetic drug targeting has been shown to be an effective strategy by manipulat
Externí odkaz: https://doaj.org/article/100a4b2eb45e44b29d55d6d9218f5d53
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4
Precision medicine for liver tumours with quantitative MRI and whole genome sequencing (Precision1 trial): study protocol for observational cohort study
Autor: Fenella K Welsh, John J Connell, Matt Kelly, Sarah Gooding, Rajarshi Banerjee, Myrddin Rees
Publikováno v: BMJ Open. 12:e057163
IntroductionRadiogenomic analysis of patients being considered for liver resection is seldom performed in the clinic despite recent evidence indicating that quantitative MRI could improve posthepatectomy outcomes. Meanwhile, the increasingly accessib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3585df1166d452d4a1ce605a35ab09
https://doi.org/10.1136/bmjopen-2021-057163
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6
Selective permeabilization of the blood-brain barrier at sites of metastasis
Autor: John J, Connell, Grégoire, Chatain, Bart, Cornelissen, Katherine A, Vallis, Alastair, Hamilton, Len, Seymour, Daniel C, Anthony, Nicola R, Sibson
Publikováno v: Journal of the National Cancer Institute. 105(21)
Effective chemotherapeutics for primary systemic tumors have limited access to brain metastases because of the blood-brain barrier (BBB). The aim of this study was to develop a strategy for specifically permeabilizing the BBB at sites of cerebral met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4b8eebec4c7488a803a8265ade31c91
https://pubmed.ncbi.nlm.nih.gov/24165949
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7
Structural and functional effects of metastases in rat brain determined by multimodal MRI
Autor: Sébastien, Serres, Christopher J, Martin, Manuel, Sarmiento Soto, Claire, Bristow, Emma R, O'Brien, John J, Connell, Alexandre A, Khrapitchev, Nicola R, Sibson
Publikováno v: International journal of cancer. 134(4)
Metastasis to the brain results in significant impairment of brain function and poor patient survival. Currently, magnetic resonance imaging (MRI) is under-utilised in monitoring brain metastases and their effects on brain function. Here, we sought t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fec2c8255b973fbd5fe457aaf80fb6a
https://pubmed.ncbi.nlm.nih.gov/23913394
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8
Akademický článek
Comparative genomics and transcriptomics reveal differences in effector complement and expression between races of Fusarium oxysporum f.sp. lactucae .
Autor: Bates HJ; NIAB, Cambridge, United Kingdom., Pike J; Warwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, United Kingdom., Price RJ; NIAB, Cambridge, United Kingdom., Jenkins S; Warwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, United Kingdom., Connell J; NIAB, Cambridge, United Kingdom., Legg A; Warwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, United Kingdom., Armitage A; NIAB, Cambridge, United Kingdom., Harrison RJ; NIAB, Cambridge, United Kingdom., Clarkson JP; Warwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, United Kingdom.
Publikováno v: Frontiers in plant science [Front Plant Sci] 2024 Oct 10; Vol. 15, pp. 1415534. Date of Electronic Publication: 2024 Oct 10 (Print Publication: 2024).
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9
Akademický článek
Genetic dissection of the tissue-specific roles of type III effectors and phytotoxins in the pathogenicity of Pseudomonas syringae pv. syringae to cherry.
Autor: Vadillo-Dieguez A; NIAB, Cambridge, UK.; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Zeng Z; NIAB, Cambridge, UK., Mansfield JW; Faculty of Natural Sciences, Imperial College London, London, UK., Grinberg NF; NIAB, Cambridge, UK., Lynn SC; NIAB, Cambridge, UK., Gregg A; NIAB, Cambridge, UK., Connell J; NIAB, Cambridge, UK., Harrison RJ; NIAB, Cambridge, UK.; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK.; Faculty of Natural Sciences, Plant Science Group, Wageningen University and Research, Wageningen, Netherlands., Jackson RW; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Hulin MT; NIAB, Cambridge, UK.; Department of Plant Soil & Microbial Sciences, Michigan State University, East Lansing, USA.
Publikováno v: Molecular plant pathology [Mol Plant Pathol] 2024 Apr; Vol. 25 (4), pp. e13451.
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10
Akademický článek
The Role of the Multiparametric MRI LiverMultiScan TM in the Quantitative Assessment of the Liver and Its Predicted Clinical Applications in Patients Undergoing Major Hepatic Resection for Colorectal Liver Metastasis.
Autor: Chouari T; MATTU, The Leggett Building, Daphne Jackson Road, Guildford GU2 7WG, UK.; Department of Hepato-Pancreato-Biliary (HPB) Surgery, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK.; Oncology Section, Department of Clinical and Experimental Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford GU2 7WG, UK., Merali N; MATTU, The Leggett Building, Daphne Jackson Road, Guildford GU2 7WG, UK.; Department of Hepato-Pancreato-Biliary (HPB) Surgery, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK.; Oncology Section, Department of Clinical and Experimental Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford GU2 7WG, UK., La Costa F; Department of Hepato-Pancreato-Biliary (HPB) Surgery, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK., Santol J; Department of Surgery, HPB Center, Vienna Health Network, Clinic Favoriten and Sigmund Freud Private University, 1090 Vienna, Austria.; Institute of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria., Chapman S; Department of Radiology, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK., Horton A; Department of Radiology, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK., Aroori S; Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery and Transplant Surgery, Derriford Hospital, Plymouth PL6 8DH, UK., Connell J; Perspectum Ltd., Oxford OX4 2LL, UK., Rockall TA; MATTU, The Leggett Building, Daphne Jackson Road, Guildford GU2 7WG, UK.; Oncology Section, Department of Clinical and Experimental Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford GU2 7WG, UK., Mole D; Clinical Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh EH10 5HF, UK.; Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, Edinburgh EH105HF, UK., Starlinger P; Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Mayo Clinic, Rochester, MN 55902, USA.; Center of Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.; Department of Surgery, Medical University of Vienna, General Hospital, 1090 Vienna, Austria., Welsh F; Hepato-Biliary Unit, Hampshire Hospitals Foundation Trust, Basingstoke, Hampshire RG24 9NA, UK., Rees M; Hepato-Biliary Unit, Hampshire Hospitals Foundation Trust, Basingstoke, Hampshire RG24 9NA, UK., Frampton AE; MATTU, The Leggett Building, Daphne Jackson Road, Guildford GU2 7WG, UK.; Department of Hepato-Pancreato-Biliary (HPB) Surgery, Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK.; Oncology Section, Department of Clinical and Experimental Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford GU2 7WG, UK.
Publikováno v: Cancers [Cancers (Basel)] 2023 Oct 05; Vol. 15 (19). Date of Electronic Publication: 2023 Oct 05.
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