Zobrazeno 1 - 10
of 10
pro vyhledávání: '"John J Castorino"'
Embryo development inside female salamander (Ambystoma jeffersonianum-laterale) prior to egg laying.
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91919 (2014)
The length of embryo retention prior to oviposition is a critical evolutionary trait. In all oviparous salamanders, which include the vast majority of species in the order, fertilization is thought to occur at the time of egg laying. Embryos then ent
Externí odkaz:
https://doaj.org/article/ba99c639af1d455199549a5e68671bd1
Supplementary Figure 1 from Monocarboxylate Transporter 4 Regulates Maturation and Trafficking of CD147 to the Plasma Membrane in the Metastatic Breast Cancer Cell Line MDA-MB-231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dce6b2ba6102bef94e7dfc131ed854
https://doi.org/10.1158/0008-5472.22368140.v1
https://doi.org/10.1158/0008-5472.22368140.v1
Metastatic cancer cells increase glucose consumption and metabolism via glycolysis, producing large quantities of lactate. Recent work has shown that lactate efflux is mediated by monocarboxylate transporters (MCT), which are composed of a catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04616675e3d08ed9d1a1dabad4ef9d8d
https://doi.org/10.1158/0008-5472.c.6495830.v1
https://doi.org/10.1158/0008-5472.c.6495830.v1
Publikováno v:
Cancer Research. 67:4182-4189
Metastatic cancer cells increase glucose consumption and metabolism via glycolysis, producing large quantities of lactate. Recent work has shown that lactate efflux is mediated by monocarboxylate transporters (MCT), which are composed of a catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bdd619d4d25a28a405db02c8599cf4
https://doi.org/10.1158/0008-5472.can-06-3184
https://doi.org/10.1158/0008-5472.can-06-3184
Autor:
Zixuan Wang, Arvydas Maminishkis, Jeffrey Adijanto, Nancy J. Philp, John J. Castorino, Gerald B. Grunwald
Publikováno v:
The Journal of biological chemistry. 287(24)
The retinal pigment epithelium (RPE) plays a fundamental role in maintaining visual function and dedifferentiation of RPE contributes to the pathophysiology of several ocular diseases. To identify microRNAs (miRNAs) that may be involved in RPE differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10dd5729af2c0d9929032a79a16f82a
https://pubmed.ncbi.nlm.nih.gov/22523078
https://pubmed.ncbi.nlm.nih.gov/22523078
Autor:
Sylvie Deborde, Enrique Rodriguez-Boulan, Shannon M. Gallagher-Colombo, Ami A. Deora, Ryan Schreiner, Nancy J. Philp, John J. Castorino
Publikováno v:
Traffic (Copenhagen, Denmark). 12(4)
Many solute transporters are heterodimers comprised of non-glycosylated catalytic and glycosylated accessory subunits. These transporters are specifically polarized to the apical or basolateral membranes of epithelia but this polarity may vary to ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ae1e26b7a6301907fcd06a94bfdefc
https://pubmed.ncbi.nlm.nih.gov/21199217
https://pubmed.ncbi.nlm.nih.gov/21199217
Publikováno v:
American journal of physiology. Cell physiology. 296(3)
Monocarboxylate transporter (MCT) 4 is a heteromeric proton-coupled lactate transporter that is noncovalently linked to the extracellular matrix metalloproteinase inducer CD147 and is typically expressed in glycolytic tissues. There is increasing evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62135e839b9ce5d272bdb30aac77344b
https://pubmed.ncbi.nlm.nih.gov/19073896
https://pubmed.ncbi.nlm.nih.gov/19073896
Autor:
Nancy J. Philp, Barbara Kloeckener-Gruissem, Alex V. Levin, John J. Castorino, Jessica Polishook, Paul G. FitzGerald, Eric Ostertag, Shannon M. Gallagher-Colombo
Publikováno v:
Investigative Opthalmology & Visual Science. 52:6774
SLC16A12 encodes an orphan member of the monocarboxylate transporter family, MCT12. A nonsense mutation in SLC16A12 (c.643CT; p.Q215X) causes juvenile cataract with a dominant inheritance pattern. In the present study, in vitro and in vivo experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eb33e9ff16d112baa6f5f860207391
https://doi.org/10.1167/iovs.10-6579
https://doi.org/10.1167/iovs.10-6579
Autor:
Charney ND; Harvard Forest, Harvard University, Petersham, MA, USA. noah@alumni.amherst.edu., Kubel JE; Natural Heritage & Endangered Species Program, Massachusetts Division of Fisheries and Wildlife, Westborough, MA, USA., Woodard CT; Mount Holyoke College, South Hadley, MA, USA., Carbajal-González BI; Mount Holyoke College, South Hadley, MA, USA., Avis S; Mount Holyoke College, South Hadley, MA, USA., Blyth JA; Maria Mitchell Association, Nantucket, MA, USA., Eiseman CS; Northfield, MA, USA., Castorino J; Hampshire College, Amherst, MA, USA., Malone JH; Department of Molecular and Cell Biology, University of Connecticut, Storrs, USA.
Publikováno v:
BMC developmental biology [BMC Dev Biol] 2019 Nov 12; Vol. 19 (1), pp. 21. Date of Electronic Publication: 2019 Nov 12.
Autor:
Fakhraldeen SA; From the McArdle Laboratory for Cancer Research and., Clark RJ; From the McArdle Laboratory for Cancer Research and., Roopra A; the Departments of Neuroscience., Chin EN; From the McArdle Laboratory for Cancer Research and., Huang W; Pathology and Laboratory Medicine., Castorino J; the School of Natural Sciences, Hampshire College, Amherst, Massachusetts 01002., Wisinski KB; Medicine, and., Kim T; Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin 53705-2276 and., Spiegelman VS; Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin 53705-2276 and., Alexander CM; From the McArdle Laboratory for Cancer Research and alexander@oncology.wisc.edu.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2015 May 22; Vol. 290 (21), pp. 13386-400. Date of Electronic Publication: 2015 Apr 10.