Zobrazeno 1 - 10
of 311
pro vyhledávání: '"John J, Wilson"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102971- (2024)
Summary: Efficient metabolism, or the means by which cells produce energy resources, is critical for proper effector function. Here, we present a protocol for examining the bioenergetics and mitochondrial fuel utilization of primary murine autoreacti
Externí odkaz:
https://doaj.org/article/b43702ddeede41e59e361ef86770ffa0
Autor:
Derry C Roopenian, John J Wilson, Jian Wei, Chih-Hao Chang, Sarah E Heuer, Ann E Wells, Gregory W Carter, Colleen Mayberry
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/5b0024933e1d4f3fab9481a12a9b66f9
Autor:
Peter E Lipsky, Derry C Roopenian, Amrie C Grammer, John J Wilson, Jian Wei, Andrea R Daamen, Colleen L Mayberry, Chih-Hao Chang
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/fe9cd495145944679a9f300977800315
Autor:
Ann E Wells, John J Wilson, Sarah E Heuer, John D Sears, Jian Wei, Raghav Pandey, Mauro W Costa, Catherine C Kaczorowski, Derry C Roopenian, Chih-Hao Chang, Gregory W Carter
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0299595 (2024)
ObjectiveGlycolytic inhibition via 2-deoxy-D-glucose (2DG) has potential therapeutic benefits for a range of diseases, including cancer, epilepsy, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA), and COVID-19, but the systemic effec
Externí odkaz:
https://doaj.org/article/22ce3f406d0c4edab2420289fe6e8a30
Autor:
John J. Wilson, Jian Wei, Andrea R. Daamen, John D. Sears, Elaine Bechtel, Colleen L. Mayberry, Grace A. Stafford, Lesley Bechtold, Amrie C. Grammer, Peter E. Lipsky, Derry C. Roopenian, Chih-Hao Chang
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107487- (2023)
Summary: Aberrant metabolic demand is observed in immune/inflammatory disorders, yet the role in pathogenesis remains unclear. Here, we discover that in lupus, activated B cells, including germinal center B (GCB) cells, have remarkably high glycolyti
Externí odkaz:
https://doaj.org/article/e7ca57bc1ffa4a2dbdc80de127fb14a9
Autor:
Thomas J Sproule, Robert Y Wilpan, John J Wilson, Benjamin E Low, Yudai Kabata, Tatsuo Ushiki, Riichiro Abe, Michael V Wiles, Derry C Roopenian, John P Sundberg
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293218 (2023)
The Lamc2jeb junctional epidermolysis bullosa (EB) mouse model has been used to demonstrate that significant genetic modification of EB symptoms is possible, identifying as modifiers Col17a1 and six other quantitative trait loci, several with strong
Externí odkaz:
https://doaj.org/article/658a1999797249b9a32a5a0a6180cfda
Autor:
Peter E Lipsky, Derry C Roopenian, Amrie C Grammer, John J Wilson, Jian Wei, Andrea R Daamen, John D Sears, Elaine Bechtel, Colleen L Mayberry, Grace A Stafford, Chih-Hao Chang
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/11dbf98d77d84b0cb4c3085a4d41ab6e
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T follicular helper (Tfh) cells provide support to B cells upon arrival in the germinal center, and thus are critical for the generation of a robust adaptive immune response. Tfh express specific transcription factors and cellular receptors including
Externí odkaz:
https://doaj.org/article/9d18a628d49d461b942f26bf255858dd
Autor:
Peter E Lipsky, Derry C Roopenian, Amrie C Grammer, John J Wilson, Jian Wei, Andrea R Daamen, John D Sears, Elaine Bechtel, Colleen L Mayberry, Grace A Stafford, Chih-Hao Chang
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/c91b8573a92c4dc6aa926ec86e047276
Autor:
Scott K. Crawford, Darryl Thelen, Janice M. Yakey, Bryan C. Heiderscheit, John J. Wilson, Kenneth S. Lee
Publikováno v:
Eur Radiol
Ultrasound often corroborates clinical diagnosis of Achilles tendinopathy (AT). Traditional measures assess macromorphological features or use qualitative grading scales, primarily focused within the free tendon. Shear wave imaging can non-invasively