Zobrazeno 1 - 10
of 166
pro vyhledávání: '"John J, Peluso"'
Publikováno v:
F&S Science. 4:121-132
Autor:
John J. Peluso
Publikováno v:
Cells, Vol 11, Iss 10, p 1632 (2022)
How progesterone influences ovarian follicle growth is a difficult question to answer because ovarian cells synthesize progesterone and express not only the classic nuclear progesterone receptor but also members of the progestin and adipoQ receptor f
Externí odkaz:
https://doaj.org/article/f54f8a9d614b4577846e6626cab75e21
Publikováno v:
Journal of Assisted Reproduction and Genetics.
Autor:
John J. Peluso, James K. Pru
Publikováno v:
Cancers, Vol 13, Iss 5953, p 5953 (2021)
Cancers
Cancers
Simple Summary Ovarian and endometrial cancers occur frequently and can be lethal. Recently, progesterone receptor membrane component (PGRMC) 1 and PGRMC2 have been shown to be highly expressed in these cancers and play important roles in promoting t
Autor:
Enrique Saez, Verena Albert, Andrea Galmozzi, Jae Y. Lee, Bernard P. Kok, Christopher G. Parker, C. Godio, Roberto Spreafico, Benjamin F. Cravatt, Arthur S. Kim, James K. Pru, Gary Siuzdak, Douglas J. Kojetin, John J. Peluso, J. Rafael Montenegro-Burke, Sarah A. Mosure, Rigo Cintron-Colon, Laura A. Solt, Bruno Conti, William Webb
Publikováno v:
Nature
Haem is an essential prosthetic group of numerous proteins and a central signalling molecule in many physiologic processes1,2. The chemical reactivity of haem means that a network of intracellular chaperone proteins is required to avert the cytotoxic
Autor:
John J Peluso
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2013)
Progesterone (P4) is synthesized in the ovary and acts directly on granulosa cells of developing ovarian follicles to suppress their rate of mitosis and apoptosis. Granulosa cells do not express nuclear progesterone receptor (PGR) but rather progeste
Externí odkaz:
https://doaj.org/article/3be1891b7d934f6e88977cf234ad033a
Autor:
John J. Peluso, Alison Bartolucci
Publikováno v:
Biology of reproduction. 104(2)
During the last few decades, millions of healthy children have been born with the aid of in vitro fertilization (IVF). This success belies the fact that IVF treatment is comprised of a complex series of interventions starting with a customized contro
Publikováno v:
Biology of reproduction. 103(1)
MicroRNA-21 is expressed in bovine, murine, and human cumulus cells with its expression in murine and bovine cumulus cells correlated with oocyte developmental potential. The aim of this study was to assess the relationship between cumulus cell MIR-2
Publikováno v:
Biology of Reproduction. 96:843-854
The present studies were designed to determine whether progesterone (P4)-progesterone receptor membrane component 1 (PGRMC1) signaling is able to attenuate the apoptotic effects of oxidative stress induced by hydrogen peroxide (H2O2). To achieve this
Publikováno v:
Biol Reprod
Progesterone receptor membrane component 1 (PGRMC1) interacts with PGRMC2, and disrupting this interaction in spontaneously immortalized granulosa cells (SIGCS) leads to an inappropriate entry into the cell cycle, mitotic arrest, and ultimately cell