Zobrazeno 1 - 10
of 39
pro vyhledávání: '"John J, Grygiel"'
Autor:
David I. Quinn, James G. Kench, Phillip D. Stricker, Warick Delprado, John J. Grygiel, Lisa G. Horvath, Kate L. Mahon, Judith Grogan, Susan Henshall, Anne Maree Haynes, Jennifer Turner
Publikováno v:
British Journal of Cancer
Background After radical prostatectomy (RP) for prostate cancer (PC), p53 alterations predict biochemical relapse (BCR), however, recent evidence suggests that metastatic relapse (MR) not BCR is a surrogate for PC specific mortality (PCSM). This upda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669bc54f6563a6e0cb28acd87c522c63
https://doi.org/10.1038/s41416-019-0549-8
https://doi.org/10.1038/s41416-019-0549-8
Autor:
James G. Kench, Robert L. Sutherland, David I. Quinn, Susan M. Henshall, Phillip D. Stricker, Andrew V. Biankin, Lisa G. Horvath, Sarah A. Eggleton, John J. Grygiel
Publikováno v:
JNCI: Journal of the National Cancer Institute. 98:1420-1424
The risk of metastatic progression for prostate cancer patients who undergo radical prostatectomy is best estimated presently based on prostate-specific antigen (PSA) doubling time (PSADT). However, additional markers of risk are needed to identify p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3f13ef71d9092cdbaa014e81b4ea3a
https://doi.org/10.1093/jnci/djj378
https://doi.org/10.1093/jnci/djj378
Autor:
John J. Grygiel, Phillip D. Stricker, Robert L. Sutherland, Raji Kooner, Lisa G. Horvath, David Golovsky, Gordon F. O'Neill, James G. Kench, Phillip Brenner, Susan M. Henshall, Jennifer Turner
Publikováno v:
The Prostate. 59:234-242
BACKGROUND The role of the bone morphogenetic protein (BMP) pathway in prostate cancer (PC) is unclear. This study aimed to characterize aspects of the BMP pathway in PC by assessing BMP2, Smad8, and Smad4 expression in normal, hyperplastic, and mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3b357a573ba55f8326c2bbf851aef3
https://doi.org/10.1002/pros.10361
https://doi.org/10.1002/pros.10361
Autor:
C. Soon Lee, Susan M. Henshall, David Golovsky, Lisa G. Horvath, Raji Kooner, James G. Kench, Phillip D. Stricker, Robert L. Sutherland, Gordon F. O'Neill, John J. Grygiel, Phillip Brenner
Publikováno v:
International Journal of Cancer. 113:415-422
Beta-catenin in its role as a nuclear signaling molecule has been implicated in prostate carcinogenesis primarily through modulation of androgen receptor activity. We defined the pattern of beta-catenin protein expression in the nuclei of normal, hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3427d975d8e42c584d41cb4eec5f9b
https://doi.org/10.1002/ijc.20599
https://doi.org/10.1002/ijc.20599
Autor:
David Golovsky, John J. Grygiel, Phillip D. Stricker, Warick Delprado, Kris K. Rasiah, Raji Kooner, Anne Maree Haynes, Phillip Brenner, Jennifer Turner, Robert L. Sutherland, Susan M. Henshall, Gordon F. O'Neill
Publikováno v:
Cancer. 98:2560-2565
BACKGROUND In the current study, the authors sought to further stratify the prognosis of patients with Gleason score (GS) 7 prostate carcinoma. They assessed the influence on outcome of a predominant poorly differentiated Gleason pattern (primary Gle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9965621d37f45934f3fd4cf2affb7aae
https://doi.org/10.1002/cncr.11850
https://doi.org/10.1002/cncr.11850
Autor:
Susan Henshall, Makato Ohori, Patrick A. Kupelian, Peter T. Scardino, David I. Quinn, Pierre I. Karakiewicz, Markus Graefen, Claudia Gerigk, Christopher Morash, Eric A. Klein, Michael W. Kattan, Andreas Erbersdobler, Farhang Rabbani, Peter G. Hammerer, Ilias Cagiannos, Robert L. Sutherland, Hartwig Huland, Victor E. Reuter, Phillip D. Stricker, John J. Grygiel, James A. Eastham
Publikováno v:
Journal of Urology. 170:1798-1803
We developed a preoperative nomogram for prediction of lymph node metastases in patients with clinically localized prostate cancer.The study was a retrospective, nonrandomized analysis of 7,014 patients treated with radical prostatectomy at 6 institu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66734e8bd81e7d54c30e5fdfa55ad479
https://doi.org/10.1097/01.ju.0000091805.98960.13
https://doi.org/10.1097/01.ju.0000091805.98960.13
Autor:
Jennifer Turner, Robert L. Sutherland, Phillip Brenner, Susan M. Henshall, Warick Delprado, David I. Quinn, Raji Kooner, Phillip D. Stricker, David Golovsky, John J. Grygiel, Gordon F. O'Neill
Publikováno v:
Cancer. 97:1884-1893
BACKGROUND Predicting outcome for men with clinically localized prostate carcinoma treated with curative intent remains imprecise and further evaluation of accepted and potential predictive factors is needed. METHODS The authors studied 696 men with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbbafd2069704ac9c18936353890cb8e
https://doi.org/10.1002/cncr.11263
https://doi.org/10.1002/cncr.11263
Autor:
Mark F. Wildhagen, Fritz H. Schröder, James A. Eastham, Markus Graefen, David I. Quinn, Theo van der Kwast, Pierre I. Karakiewicz, Bernard H. Bochner, Hartwig Huland, Peter G. Hammerer, Robert L. Sutherland, Alexander Haese, Phillip D. Stricker, Michael W. Kattan, Jean B. de Kernion, Peter T. Scardino, Susan Henshall, Donald G. Skinner, Thomas Cangiano, Patrick A. Kupelian, Andreas Erbersdobler, Ilias Cagiannos, Gary Lieskovsky, John J. Grygiel, Eric A. Klein
Publikováno v:
Journal of Clinical Oncology. 20:3206-3212
PURPOSE: We evaluated the predictive accuracy of a recently published preoperative nomogram for prostate cancer that predicts 5-year freedom from recurrence. We applied this nomogram to patients from seven different institutions spanning three contin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10f47f0cbe2e5222b60017dbfac3c9a
https://doi.org/10.1200/jco.2002.12.019
https://doi.org/10.1200/jco.2002.12.019
Autor:
Mark F. Wildhagen, Eric Klein, Patrick A. Kupelian, Michael W. Kattan, Thomas Cangiano, Phillip D. Stricker, Jean B. de Kernion, Fritz H. Schröder, Markus Graefen, Robert L. Sutherland, David I. Quinn, Susan Henshall, John J. Grygiel, Peter T. Scardino, Pierre I. Karakiewicz, Ilias Cagiannos
Publikováno v:
Journal of Clinical Oncology. 20:951-956
PURPOSE: A postoperative nomogram for prostate cancer was developed at Baylor College of Medicine. This nomogram uses readily available clinical and pathologic variables to predict 7-year freedom from recurrence after radical prostatectomy. We evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd61d5871aa799cb168448b03add6c8
https://doi.org/10.1200/jco.2002.20.4.951
https://doi.org/10.1200/jco.2002.20.4.951
Autor:
C. Soon Lee, Darren N. Saunders, Jayne E. Lelliott, John J. Grygiel, Susan M. Henshall, Robert L. Sutherland, Lisa G. Horvath, Elizabeth D. Williams, James G. Kench
Publikováno v:
The Prostate. 67(10)
BACKGROUND Secreted frizzled-related proteins (sFRP4) inhibits Wnt signaling and thus cellular proliferation in androgen-independent prostate cancer cells in vitro. However, increased expression of membranous sFRP4 is associated with a good prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfeeb934ff900db64ad9eab832be1fbf
https://pubmed.ncbi.nlm.nih.gov/17476687
https://pubmed.ncbi.nlm.nih.gov/17476687