Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John Inthavongsay"'
Autor:
Stéphane De Lombaert, Diane M. Hargrove, Christine M. Mack, Charles A. Blum, David A. Griffith, Martin Sanders, Colin R. Rose, Tristan S. Maurer, John Inthavongsay, Lee E. Klade, Philip A. Carpino
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:2641-2645
A novel series of pyrazolo[1,5-a]pyrimidine derivatives was synthesized and evaluated as NPY Y1R antagonists. High binding affinity and selectivity were achieved with C3 trisubstituted aryl groups and C7 substituted 2-(tetrahydro-2H-pyran-4-ylamino)e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0634752496c827b718a2e96252d0e99
https://doi.org/10.1016/j.bmcl.2010.12.116
https://doi.org/10.1016/j.bmcl.2010.12.116
Autor:
Chris Manley, Charles R. Heap, John Inthavongsay, Xuemei Chen, Yi Wang, Yiu-Yin Cheung, Ruifang Wang, Keith D. Barnes, Matthew D. Johnson, Bryan Duffy, Charles E. Schwartz, Ravi Krishnamoorthy, Melissa L. Allard, Stephan Steffke, Deepu Varughese
Publikováno v:
Tetrahedron Letters. 52:2623-2626
The enantioselective total synthesis of Resolvin E1 (RvE1), a naturally occurring small molecule mediator of inflammation resolution, is reported. Two routes are presented, both modular and convergent in nature, with an excellent control of all stere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69500efc3d08b709579a6bef7f2bd425
https://doi.org/10.1016/j.tetlet.2011.03.035
https://doi.org/10.1016/j.tetlet.2011.03.035
Autor:
Oicheng Ng, John Inthavongsay, Theresa C. Wilson, Bruce Allen Lefker, Anthony Michael Campeta, Ann S. Wright, Hada William Andrew, John R. Hadcock, David A. Tess, Lydia C. Pan, K.L. Chidsey-Frink, F.Michael Mangano, Steven M. Toler, Colin R. Rose, Ewell R. Cook, Li Yu, C.M. Pirie, David F. Nickerson, Shari L. DeNinno, Joseph DiBrino, John A. Ragan, Paul DaSilva-Jardine, Michelle A. Mullins, David D. Thompson, Philip A. Carpino, Michael P. Zawistoski
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:581-590
Novel pyrazolinone-piperidine dipeptide derivatives were synthesized and evaluated as growth hormone secretagogues (GHSs). Two analogues, capromorelin ( 5 , CP-424391-18, hGHS-R1a K i =7 nM, rat pituicyte EC 50 =3 nM) and the des-methyl analogue 5c (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee90ef449e2e33cb480f51243353e6df
https://doi.org/10.1016/s0968-0896(02)00433-9
https://doi.org/10.1016/s0968-0896(02)00433-9
Autor:
John Inthavongsay, Theresa C. Wilson, Li Yu, Colin R. Rose, Hada William Andrew, Oicheng Ng, John R. Hadcock, David D. Thompson, David F. Nickerson, Michelle A. Mullins, Steven M. Toler, F.Michael Mangano, Paul DaSilva-Jardine, Ewell R. Cook, Bruce Allen Lefker, C.M. Pirie, David A. Tess, Lydia C. Pan, Lewis Sharon K, Michael P. Zawistoski, Ann S. Wright, Joseph DiBrino, K.L. Chidsey-Frink, Murray Marianne C, Philip A. Carpino, Shari L. DeNinno, John C. Pettersen, John A. Ragan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:3279-3282
New tert -butyl, picolyl and fluorinated analogues of capromorelin ( 3 ), a short-acting growth hormone secretagogue (GHS), were prepared as part of a program to identify long-acting GHSs that increase 24-h plasma IGF-1 levels. Compounds 4c and 4d (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1be688b588cfdcb84bb787954c1dac
https://doi.org/10.1016/s0960-894x(02)00734-5
https://doi.org/10.1016/s0960-894x(02)00734-5
Autor:
Philip A, Carpino, Bruce A, Lefker, Steven M, Toler, Lydia C, Pan, John R, Hadcock, Ewell R, Cook, Joseph N, DiBrino, Anthony M, Campeta, Shari L, DeNinno, Kristin L, Chidsey-Frink, William A, Hada, John, Inthavongsay, F Michael, Mangano, Michelle A, Mullins, David F, Nickerson, Oicheng, Ng, Christine M, Pirie, John A, Ragan, Colin R, Rose, David A, Tess, Ann S, Wright, Li, Yu, Michael P, Zawistoski, Paul A, DaSilva-Jardine, Theresa C, Wilson, David D, Thompson
Publikováno v:
Bioorganicmedicinal chemistry. 11(4)
Novel pyrazolinone-piperidine dipeptide derivatives were synthesized and evaluated as growth hormone secretagogues (GHSs). Two analogues, capromorelin (5, CP-424391-18, hGHS-R1a K(i)=7 nM, rat pituicyte EC(50)=3 nM) and the des-methyl analogue 5c (hG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92b65a6afa8270ad7ecd34dd391b8451
https://pubmed.ncbi.nlm.nih.gov/12538023
https://pubmed.ncbi.nlm.nih.gov/12538023
Autor:
Yi Wang, Xuejin Liu, Xuemei Chen, Zhixing Shan, Yiu-Yin Cheung, Keith D. Barnes, Chris Manley, Charles E. Schwartz, Ruifang Wang, Bryan Duffy, Charles R. Heap, Deepu Varughese, Matthew D. Johnson, Stephan Steffke, Melissa L. Allard, Ravi Krishnamoorthy, John Inthavongsay, Qiang Yang
Publikováno v:
Tetrahedron Letters. 52:6512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c5519e584c8824aba6932c59410180
https://doi.org/10.1016/j.tetlet.2011.10.001
https://doi.org/10.1016/j.tetlet.2011.10.001