Zobrazeno 1 - 10
of 26
pro vyhledávání: '"John I. Toohey"'
Autor:
John I. Toohey, Arthur J. L. Cooper
Publikováno v:
Molecules, Vol 19, Iss 8, Pp 12789-12813 (2014)
The understanding of sulfur bonding is undergoing change. Old theories on hypervalency of sulfur and the nature of the chalcogen-chalcogen bond are now questioned. At the same time, there is a rapidly expanding literature on the effects of sulfur in
Externí odkaz:
https://doaj.org/article/e4cd9b2785734ada9bffa960eddcf5d3
Autor:
John I. Toohey
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 8334-8349 (2014)
The relationship of sulfur amino acids to diet-induced fatty liver was established 80 years ago, with cystine promoting the condition and methionine preventing it. This relationship has renewed importance today because diet-induced fatty liver is rel
Externí odkaz:
https://doaj.org/article/b91aedaa8d4e4660b321aa21c3a426b2
Autor:
John I. Toohey
Publikováno v:
Molecules, Vol 22, Iss 4, p 582 (2017)
Evidence from several fields of investigation lead to the hypothesis that the sulfur atom is involved in vitamin B12-dependent methyl group transfer. To compile the evidence, it is necessary to briefly review the following fields: methylation, the ne
Externí odkaz:
https://doaj.org/article/01f96d9438b44257a095c8b0eebc54b8
Autor:
John I. Toohey
Publikováno v:
Analytical Biochemistry. 413:1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f0bd5a4491e2d3572c60a7bed3d62f
https://doi.org/10.1016/j.ab.2011.01.044
https://doi.org/10.1016/j.ab.2011.01.044
Autor:
John I. Toohey
Publikováno v:
Connective Tissue Research. 49:57-61
Hyperhomocysteinemia causes connective tissue pathology. Several theories on the mechanism of homocysteine toxicity in connective tissue are reviewed briefly. A possible new mechanism was revealed recently in the discovery of a reaction in which homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb98f6273a0b32126819c7275182623
https://doi.org/10.1080/03008200801913742
https://doi.org/10.1080/03008200801913742
Autor:
John I. Toohey
Publikováno v:
Journal of Inorganic Biochemistry. 49:189-199
Hydrosulfide ion displaces OH − or CN − from cobalamin or cobinamide to give stable, brown-colored derivatives containing Co(II). Absorption maxima are at 270, 350, 415, and 528 nm for the cobalamin derivative and at 263, 330, and 434 nm for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::878c11f677a18d5869fa1455ea41fee5
https://doi.org/10.1016/0162-0134(93)80004-s
https://doi.org/10.1016/0162-0134(93)80004-s
Autor:
John I. Toohey
Publikováno v:
AIDS research and human retroviruses. 25(11)
Numerous reports have documented disturbances of sulfur metabolism in AIDS patients. There is a generalized loss of sulfur from the body, measured as cysteine and glutathione. The enzyme, cystathionase, has been shown to be greatly decreased in the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b386c278386e09ad8a0c0bc19e8507
https://pubmed.ncbi.nlm.nih.gov/19886835
https://pubmed.ncbi.nlm.nih.gov/19886835
Autor:
John I. Toohey
Publikováno v:
Cancer letters. 263(2)
Three discoveries together point the way to a potential treatment for cancer. In 1982, Poydock and colleagues found that dehydroascorbic acid has the remarkable ability to eliminate the aggressive mouse tumours, L1210, P388, Krebs sarcoma, and Ehrlic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2596748e7c195bf593c519dcb9dc0301
https://pubmed.ncbi.nlm.nih.gov/18378072
https://pubmed.ncbi.nlm.nih.gov/18378072
Autor:
John I. Toohey
Publikováno v:
BioFactors (Oxford, England). 26(1)
The mechanism by which Vitamin B12 prevents demyelination of nerve tissue is still not known. The evidence indicates that the critical site of B12 function in nerve tissue is in the enzyme, methionine synthase, in a system which requires S-adenosylme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f543d0bc2a7b933c0fcf088d64062983
https://pubmed.ncbi.nlm.nih.gov/16614482
https://pubmed.ncbi.nlm.nih.gov/16614482
Autor:
John I. Toohey
Publikováno v:
Nature Reviews Molecular Cell Biology. 13:803-803
In a recently published Review article (H2S signalling through protein sulfhydration and beyond. Nature Rev. Mol. Cell Biol. 13, 499–507 (2012))1, Paul and Snyder use the term 'sulfhydration' to define a protein modification involving hydrogen sulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc3cd0c70cd6d492957fd4f69c293c6
https://doi.org/10.1038/nrm3391-c1
https://doi.org/10.1038/nrm3391-c1