Zobrazeno 1 - 10
of 267
pro vyhledávání: '"John I. Gallin"'
Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury
Autor:
Hannah Mason, Ganesha Rai, Arina Kozyr, Nathaniel De Jonge, Emily Gliniewicz, Lars J. Berg, Gal Wald, Cayce Dorrier, Mark J. Henderson, Alexey Zakharov, Tristan Dyson, John Audley, Anthony M. Pettinato, Elias Carvalho Padilha, Pranav Shah, Xin Xu, Thomas L. Leto, Anton Simeonov, Kol A. Zarember, Dorian B. McGavern, John I. Gallin
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102611- (2023)
NADPH oxidases (NOX's), and the reactive oxygen species (ROS) they produce, play an important role in host defense, thyroid hormone synthesis, apoptosis, gene regulation, angiogenesis and other processes. However, overproduction of ROS by these enzym
Externí odkaz:
https://doaj.org/article/31bbeff5a1be41638e89f840fa625181
Autor:
Michael S. Abers, Ottavia M. Delmonte, Emily E. Ricotta, Jonathan Fintzi, Danielle L. Fink, Adriana A. Almeida de Jesus, Kol A. Zarember, Sara Alehashemi, Vasileios Oikonomou, Jigar V. Desai, Scott W. Canna, Bita Shakoory, Kerry Dobbs, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Francesco Castelli, Camillo Rossi, Duilio Brugnoni, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio’, Paolo Bonfanti, Riccardo Castagnoli, Daniela Montagna, Amelia Licari, Gian Luigi Marseglia, Emily F. Gliniewicz, Elana Shaw, Dana E. Kahle, Andre T. Rastegar, Michael Stack, Katherine Myint-Hpu, Susan L. Levinson, Mark J. DiNubile, Daniel W. Chertow, Peter D. Burbelo, Jeffrey I. Cohen, Katherine R. Calvo, John S. Tsang, NIAID COVID-19 Consortium, Helen C. Su, John I. Gallin, Douglas B. Kuhns, Raphaela Goldbach-Mansky, Michail S. Lionakis, Luigi D. Notarangelo
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19). However, the utility of specific immune-based biomarkers to predict clinical outc
Externí odkaz:
https://doaj.org/article/feaeec76ff49437f8d320c0de85e7c30
Autor:
Artur Muszyński, Kol A. Zarember, Christian Heiss, Joseph Shiloach, Lars J. Berg, John Audley, Arina Kozyr, David E. Greenberg, Steven M. Holland, Harry L. Malech, Parastoo Azadi, Russell W. Carlson, John I. Gallin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3303 (2021)
Granulibacter bethesdensis can infect patients with chronic granulomatous disease, an immunodeficiency caused by reduced phagocyte NADPH oxidase function. Intact G. bethesdensis (Gb) is hypostimulatory compared to Escherichia coli, i.e., cytokine pro
Externí odkaz:
https://doaj.org/article/7742a9e28acd472eb3687d321e9e745a
Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded refer
Autor:
John I. Gallin, Frederick P Ognibene
The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and prot
Autor:
Alexander H. Yang, Brigit Sullivan, Christa S. Zerbe, Suk See De Ravin, Andrew M. Blakely, Martha M. Quezado, Beatriz E. Marciano, Jamie Marko, Alexander Ling, David E. Kleiner, John I. Gallin, Harry L. Malech, Steven M. Holland, Theo Heller
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 11:1401-1416
Autor:
John I. Gallin, Frederick P Ognibene
The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and pro
Autor:
Mark R. Gilbert, John I. Gallin, Douglas B. Kuhns, William D. Figg, Katherine R. Calvo, Terri S. Armstrong, Javier Gonzales, Heather Leeper, Marta Penas-Prado, Eric M. Burton, Brett J. Theeler, Orwa Aboud, Christine Cordova, Nicole Lollo, Christine Siegel, Nancy Garren, Ramya Antony, Lisa Boris, Kelly Mentges, Ewa Grajkowska, Matthew Lindsley, Christine Bryla, Salman Ahmad, Elizabeth Vera, Tito R. Mendoza, Madison K. Butler, Guangyang Yu, Ying Pang, Yu-Ting Su, Tristan M. Sissung, Cody J. Peer, Danielle Fink, Debra A. Long Priel, Ying Yuan, Jing Wu
Neutrophils chemotaxis video
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ada6d9d3c80de0abfde104bdf36969
https://doi.org/10.1158/1078-0432.22481867
https://doi.org/10.1158/1078-0432.22481867
Autor:
Mark R. Gilbert, John I. Gallin, Douglas B. Kuhns, William D. Figg, Katherine R. Calvo, Terri S. Armstrong, Javier Gonzales, Heather Leeper, Marta Penas-Prado, Eric M. Burton, Brett J. Theeler, Orwa Aboud, Christine Cordova, Nicole Lollo, Christine Siegel, Nancy Garren, Ramya Antony, Lisa Boris, Kelly Mentges, Ewa Grajkowska, Matthew Lindsley, Christine Bryla, Salman Ahmad, Elizabeth Vera, Tito R. Mendoza, Madison K. Butler, Guangyang Yu, Ying Pang, Yu-Ting Su, Tristan M. Sissung, Cody J. Peer, Danielle Fink, Debra A. Long Priel, Ying Yuan, Jing Wu
Clinical trial protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a20c7e105c2b869c492384e7556eeb9
https://doi.org/10.1158/1078-0432.22481876.v1
https://doi.org/10.1158/1078-0432.22481876.v1
Autor:
Mark R. Gilbert, John I. Gallin, Douglas B. Kuhns, William D. Figg, Katherine R. Calvo, Terri S. Armstrong, Javier Gonzales, Heather Leeper, Marta Penas-Prado, Eric M. Burton, Brett J. Theeler, Orwa Aboud, Christine Cordova, Nicole Lollo, Christine Siegel, Nancy Garren, Ramya Antony, Lisa Boris, Kelly Mentges, Ewa Grajkowska, Matthew Lindsley, Christine Bryla, Salman Ahmad, Elizabeth Vera, Tito R. Mendoza, Madison K. Butler, Guangyang Yu, Ying Pang, Yu-Ting Su, Tristan M. Sissung, Cody J. Peer, Danielle Fink, Debra A. Long Priel, Ying Yuan, Jing Wu
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf46029daf5c8432b52632fc9d1de3d
https://doi.org/10.1158/1078-0432.22481879
https://doi.org/10.1158/1078-0432.22481879