Zobrazeno 1 - 10
of 53
pro vyhledávání: '"John Hotchin"'
Autor:
John Hotchin, Lois (Benson) Hotchin
Publikováno v:
Science. 253:210-210
Publikováno v:
Journal of the Neurological Sciences. 72:307-318
A low virulence strain of herpes simplex type 1 was microinjected into the hippocampus of BALB/c mice. Intense replication of virus at the inoculum site was followed by spread of viral antigen to the afferent connections of the hippocampus. Surviving
Autor:
M.G. Sarngadharan, V.S. Kalyanaraman, K. Ganguly, J.M. Zhong, Y. Zeng, Stanley A. Plotkin, Frank J. O'Neill, John Hotchin, Frederick D. Baker, Joseph M. Weber, X.C. Miao, Dana Carroll, Leda H. Raptis, Claude V. Déry, Elizabeth Hornberger, Edward Sikora, Charles Hannan, Y.K. Mo
Publikováno v:
Intervirology. 19:I-V
Autor:
Dennis J. McFarland, John Hotchin
Publikováno v:
Journal of the Neurological Sciences. 79:255-265
Two strains of herpes simplex virus type 1 (HSV) were microinjected into either the hippocampus or cerebellum of two different mouse strains. Immunoperoxidase staining revealed rapid and extensive spread of virus within the hippocampus and certain of
Publikováno v:
Life Sciences. 29:777-782
We have examined the effects of peritoneal injections of d-amphetamine sulfate (d-amp) on mortality in mice inoculated peripherally and then intracerebrally (IC) infected with herpes simplex virus type 1 (HSV). On day 5 post-IC infection, the mice we
Publikováno v:
Journal of the Neurological Sciences. 56:299-310
The binding of 3H-thymidine labeled herpes simplex virus to homogenates of rodent brain regions and liver was examined. The results indicated that binding sites in the brain are distributed in a non-uniform manner, the specific pattern observed depen
Autor:
Ruth Buckley, John Hotchin
Publikováno v:
Science. 196:668-671
Scrapie is an unusual slow-virus disease of sheep which is very much like kuru and Creutzfeldt-Jakob disease, both fatal, slow neuological diseases of man. In mice, scrapie usually has an incubation period of about 6 months. Intraperitoneal inoculati
Publikováno v:
Intervirology. 19:205-212
Examination of newborn mice, inoculated intraperitoneally with high doses of scrapie virus, revealed that the virus could not be reisolated from their tissues after about 1 week following inoculation, until almost 1 year later. The inoculum was rapid
Publikováno v:
Journal of the Neurological Sciences. 48:69-79
The neurotransmitter biosynthesis enzymes tyrosine hydroxylase and choline acetyltransferase were investigated in selected brain areas of Nya: NYLAR mice infected with lymphocytic choriomeningitis (LCM) virus. Statistically significant alterations in