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pro vyhledávání: '"John Hoerter"'
Publikováno v:
The Journal of Immunology. 190:111.3-111.3
Recognition of antigen by the T cell receptor (TCR) is the key event for the T cell activation. The earliest molecular events in T cell recognition have not yet been fully described, and the TCR triggering mechanism remains a subject of controversy.
Publikováno v:
The Journal of Immunology. 188:106.50-106.50
Recognition of antigen by the T cell receptor (TCR) is the key event for the T cell activation. The earliest molecular events in T cell recognition have not yet been fully described, and the TCR triggering mechanism remains a subject of controversy.
Autor:
John Hoerter, Jeanette Ampudia, Pia Yachi, Janet Connolly, Ted Hansen, Keith Gould, Nicholas Gascoigne
Publikováno v:
The Journal of Immunology. 182:35.39-35.39
Recent work has demonstrated that endogenous or non-stimulatory peptides can enhance T-cell recognition, a finding that is unexplained by the classical model of CD8, TCR, and MHC interaction. To investigate this phenomenon, we have developed a tetrac