Zobrazeno 1 - 10
of 10
pro vyhledávání: '"John Hintze"'
Autor:
Thomas D. Madsen, Lasse H. Hansen, John Hintze, Zilu Ye, Shifa Jebari, Daniel B. Andersen, Hiren J. Joshi, Tongzhong Ju, Jens P. Goetze, Cesar Martin, Mette M. Rosenkilde, Jens J. Holst, Rune E. Kuhre, Christoffer K. Goth, Sergey Y. Vakhrushev, Katrine T. Schjoldager
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
O-glycosylation is an abundant post-translational modification but its relevance for bioactive peptides is unclear. Here, the authors detect O-glycans on almost one third of the classified peptide hormones and show that O-glycosylation can modulate p
Externí odkaz:
https://doaj.org/article/d81560792a8349198626ee05e6f9d81f
Autor:
Ida Signe Bohse Larsen, Lorenzo Povolo, Luping Zhou, Weihua Tian, Kasper Johansen Mygind, John Hintze, Chen Jiang, Verity Hartill, Katrina Prescott, Colin A. Johnson, Sureni V. Mullegama, Allyn McConkie-Rosell, Marie McDonald, Lars Hansen, Sergey Y. Vakhrushev, Katrine T. Schjoldager, Henrik Clausen, Thomas Worzfeld, Hiren J. Joshi, Adnan Halim
Publikováno v:
Larsen, I S B, Povolo, L, Zhou, L, Tian, W, Mygind, K J, Hintze, J, Jiang, C, Hartill, V, Prescott, K, Johnson, C A, Mullegama, S V, McConkie-Rosell, A, McDonald, M, Hansen, L, Vakhrushev, S Y, Schjoldager, K T, Clausen, H, Worzfeld, T, Joshi, H J & Halim, A 2023, ' The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase ', Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 21, pp. e2302584120 . https://doi.org/10.1073/pnas.2302584120
Mutations in the TMEM260 gene cause structural heart defects and renal anomalies syndrome, but the function of the encoded protein remains unknown. We previously reported wide occurrence of O-mannose glycans on extracellular immunoglobulin, plexin, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002d22943d971c680b2f7b4e379c7c4f
https://doi.org/10.1073/pnas.2302584120
https://doi.org/10.1073/pnas.2302584120
Autor:
Sergey Y. Vakhrushev, Zilu Ye, Jens P. Goetze, Mette M. Rosenkilde, Shifa Jebari, César Martín, Jens J. Holst, Tongzhong Ju, John Hintze, Lasse H Hansen, Daniel B. Andersen, Rune E. Kuhre, Katrine T. Schjoldager, Christoffer K. Goth, Thomas Daugbjerg Madsen, Hiren J. Joshi
Publikováno v:
Madsen, T D, Hansen, L H, Hintze, J, Ye, Z, Jebari, S, Andersen, D B, Joshi, H J, Ju, T, Goetze, J P, Martin, C, Rosenkilde, M M, Holst, J J, Kuhre, R E, Goth, C K, Vakhrushev, S Y & Schjoldager, K T 2020, ' An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles ', Nature Communications, vol. 11, no. 1, 4033 . https://doi.org/10.1038/s41467-020-17473-1
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Universidad de Cantabria (UC)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Universidad de Cantabria (UC)
Nature Communications
Peptide hormones and neuropeptides encompass a large class of bioactive peptides that regulate physiological processes like anxiety, blood glucose, appetite, inflammation and blood pressure. Here, we execute a focused discovery strategy to provide an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa9985415adc543865afb20b97f3994
http://hdl.handle.net/10810/49183
http://hdl.handle.net/10810/49183
Autor:
Elena Gardella, Damir Musaev, Cecilia Vitali, Emanuele Agolini, Sumeet A. Khetarpal, Kimiyo Raymond, Daniel J. Rader, Camilla Gøbel Madsen, Valentina Stanley, Antonio Novelli, Andrew C. Edmondson, W. Timothy O'Brien, Heiko Reutter, John Hintze, Kristen Liedtke, Mahmoud Y. Issa, Lars Hansen, Christina Fenger, Kevin Rostasy, Rami Abou Jamra, Maha S. Zaki, Francesca Romana Lepri, Ulla E. Petäjä-Repo, Joseph G. Gleeson, Rikke S. Møller, Silvana Briuglia, Katrine T. Schjoldager, Lorenzo Sinibaldi, Viola Alesi, Guido Rubboli, Raffaella Cusmai, Monica Zilmer
Publikováno v:
Brain
Zilmer, M, Edmondson, A C, Khetarpal, S A, Alesi, V, Zaki, M S, Rostasy, K, Madsen, C G, Lepri, F R, Sinibaldi, L, Cusmai, R, Novelli, A, Issa, M Y, Fenger, C D, Jamra, R A, Reutter, H, Briuglia, S, Agolini, E, Hansen, L, Petäjä-Repo, U E, Hintze, J, Raymond, K M, Liedtke, K, Stanley, V, Musaev, D, Gleeson, J G, Vitali, C, O’Brien, W T, Gardella, E, Rubboli, G, Rader, D J, Schjoldager, K T & Møller, R S 2020, ' Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function ', Brain, vol. 143, no. 4, pp. 1114-1126 . https://doi.org/10.1093/brain/awaa063
Zilmer, M, Edmondson, A C, Khetarpal, S A, Alesi, V, Zaki, M S, Rostasy, K, Madsen, C G, Lepri, F R, Sinibaldi, L, Cusmai, R, Novelli, A, Issa, M Y, Fenger, C D, Jamra, R A, Reutter, H, Briuglia, S, Agolini, E, Hansen, L, Petäjä-Repo, U E, Hintze, J, Raymond, K M, Liedtke, K, Stanley, V, Musaev, D, Gleeson, J G, Vitali, C, O’Brien, W T, Gardella, E, Rubboli, G, Rader, D J, Schjoldager, K T & Møller, R S 2020, ' Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function ', Brain, vol. 143, no. 4, pp. 1114-1126 . https://doi.org/10.1093/brain/awaa063
Congenital disorders of glycosylation are a growing group of rare genetic disorders caused by deficient protein and lipid glycosylation. Here, we report the clinical, biochemical, and molecular features of seven patients from four families with GALNT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a69c26d8205f2d4c42003940e13c92
https://europepmc.org/articles/PMC7534148/
https://europepmc.org/articles/PMC7534148/
Autor:
Thomas Daugbjerg Madsen, Adam D. Linstedt, Collin Bachert, Hiren J. Joshi, John Hintze, Christoffer K. Goth, Ulla Mandel, Eric P. Bennett, Sergey Y. Vakhrushev, Zilu Ye, Katrine T. Schjoldager, Yoshiki Narimatsu
Publikováno v:
Journal of Biological Chemistry. 293:19064-19077
The GalNAc-type O-glycoproteome is orchestrated by a large family of polypeptide GalNAc-transferase isoenzymes (GalNAc-Ts) with partially overlapping contributions to the O-glycoproteome besides distinct nonredundant functions. Increasing evidence in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bbe5de177b2759d5b0673a96713a927
https://doi.org/10.1074/jbc.ra118.004516
https://doi.org/10.1074/jbc.ra118.004516
Autor:
John, Hintze, Zilu, Ye, Yoshiki, Narimatsu, Thomas Daugbjerg, Madsen, Hiren J, Joshi, Christoffer K, Goth, Adam, Linstedt, Collin, Bachert, Ulla, Mandel, Eric P, Bennett, Sergey Y, Vakhrushev, Katrine T, Schjoldager
Publikováno v:
The Journal of biological chemistry. 293(49)
The GalNAc-type O-glycoproteome is orchestrated by a large family of polypeptide GalNAc-transferase isoenzymes (GalNAc-Ts) with partially overlapping contributions to the O-glycoproteome besides distinct nonredundant functions. Increasing evidence in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c23d3c5c7cfa102b0f5e53c964d77a2
https://pubmed.ncbi.nlm.nih.gov/30327431
https://pubmed.ncbi.nlm.nih.gov/30327431
Autor:
Annageldi Tayyrov, Andreas Essig, Anja Kombrink, Pauli T. Kallio, Natalia Dürig, John Hintze, Sebastian Micheller, Markus Aebi, Yasemin van Heuvel, Markus Künzler, Chia-Wei Lin, Martina Stöckli
Publikováno v:
The ISME Journal
Bacteria are the main nutritional competitors of saprophytic fungi during colonization of their ecological niches. This competition involves the mutual secretion of antimicrobials that kill or inhibit the growth of the competitor. Over the last years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0db51320181e0859ed0cd653acbd06
https://pubmed.ncbi.nlm.nih.gov/30301946
https://pubmed.ncbi.nlm.nih.gov/30301946
Autor:
Lars Hansen, Cathy Mitchelmore, Eric P. Bennett, John Hintze, Sylvester Larsen, Raquel Almeida, Jesper T. Troelsen, Johanne Davidsen, Leonor David, Rita Pinto, Mehmet Coşkun
Publikováno v:
Pinto, R, Hansen, L, Hintze, J B H, Almeida, R, Larsen, S, Coskun, M, Davidsen, J, Mitchelmore, C, David, L, Troelsen, J T & Bennett, E P 2017, ' Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression ', Nucleic Acids Research, vol. 45, no. 13, e123 . https://doi.org/10.1093/nar/gkx371
Nucleic Acids Research
Nucleic Acids Research
Tetracycline-based inducible systems provide powerful methods for functional studies where gene expression can be controlled. However, the lack of tight control of the inducible system, leading to leakiness and adverse effects caused by undesirable t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e7effa20919417b33a562573067005
https://curis.ku.dk/ws/files/182748720/watermark.pdf
https://curis.ku.dk/ws/files/182748720/watermark.pdf
Autor:
John&Hintze
Publikováno v:
Money Management Executive. 8/7/2006, Vol. 14 Issue 31, p6-15. 2p.
Autor:
By John Hintze
Publikováno v:
Bank Investment Consultant. Dec2004, Vol. 12 Issue 12, p6-12. 2p.