Zobrazeno 1 - 10
of 152
pro vyhledávání: '"John Hays"'
Autor:
Monica Hoyos Flight, Joyce Tait, Theo Chronopoulos, Monica Betancor, Pauline Wischhusen, Emily Burton, Helen Masey O'Neill, Kim van derHeul, John Hays, Peter Rowe
Publikováno v:
Engineering Biology, Vol 8, Iss 1, Pp 16-29 (2024)
Abstract The British Standards Institution's Publicly Available Specification 440 (PAS 440) provides a Responsible Innovation Framework (RIF) that companies can use to continuously monitor the societal, environmental and health benefits and risks of
Externí odkaz:
https://doaj.org/article/c4f208f7320a45118e418425538fdf5e
Autor:
Ashish Manne, Ashwini Esnakula, Ankur Sheel, Amir Sara, Upender Manne, Ravi Kumar Paluri, Kai He, Wancai Yang, Davendra Sohal, Anup Kasi, Anne M. Noonan, Arjun Mittra, John Hays, Sameek Roychowdhury, Pannaga Malalur, Shafia Rahman, Ning Jin, Jordan M. Cloyd, Susan Tsai, Aslam Ejaz, Kenneth Pitter, Eric Miller, Kannan Thanikachalam, Mary Dillhoff, Lianbo Yu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9041 (2024)
Neoadjuvant therapy (NAT) for early-stage pancreatic ductal adenocarcinoma (PDA) has recently gained prominence. We investigated the clinical significance of mucin 5 AC (MUC5AC), which exists in two major glycoforms, a less-glycosylated immature isof
Externí odkaz:
https://doaj.org/article/b1fab2da00824cabbddfa7f1e921ad46
Autor:
Dimard E. Foudraine, Camiel N. M. Aarents, Agnes A. Wattel, Ria van Boxtel, Nikolaos Strepis, Marian T. ten Kate, Annelies Verbon, Theo M. Luider, Corné H. W. Klaassen, John Hays, Lennard J. M. Dekker, Jan Tommassen, Wil H. F. Goessens
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
While Extended-Spectrum β-Lactamases (ESBL) and AmpC β-lactamases barely degrade carbapenem antibiotics, they are able to bind carbapenems and prevent them from interacting with penicillin-binding proteins, thereby inhibiting their activity. Furthe
Externí odkaz:
https://doaj.org/article/b25331abc8994682abe606578a79c7c4
MDM2-Dependent Rewiring of Metabolomic and Lipidomic Profiles in Dedifferentiated Liposarcoma Models
Autor:
Andrew Patt, Bryce Demoret, Colin Stets, Kate-Lynn Bill, Philip Smith, Anitha Vijay, Andrew Patterson, John Hays, Mindy Hoang, James L. Chen, Ewy A. Mathé
Publikováno v:
Cancers, Vol 12, Iss 8, p 2157 (2020)
Dedifferentiated liposarcoma (DDLPS) is an aggressive mesenchymal cancer marked by amplification of MDM2, an inhibitor of the tumor suppressor TP53. DDLPS patients with higher MDM2 amplification have lower chemotherapy sensitivity and worse outcome t
Externí odkaz:
https://doaj.org/article/ffc48958ca1b4ab08f4f626dc9bd20f5
Autor:
Eliza W. Beal, Lorena P. Suarez-Kelly, Charles W. Kimbrough, Fabian M. Johnston, Jonathan Greer, Daniel E. Abbott, Courtney Pokrzywa, Mustafa Raoof, Byrne Lee, Travis E. Grotz, Jennifer L. Leiting, Keith Fournier, Andrew J. Lee, Sean P. Dineen, Benjamin Powers, Jula Veerapong, Joel M. Baumgartner, Callisia Clarke, Harveshp Mogal, Marti C. Russell, Mohammed Y. Zaidi, Sameer H. Patel, Vikrom Dhar, Laura Lambert, Ryan J. Hendrix, John Hays, Sherif Abdel-Misih, Jordan M. Cloyd
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 3, p 748 (2020)
Cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with improved survival for patients with colorectal peritoneal metastases (CR-PM). However, the role of neoadjuvant chemotherapy (NAC) prior t
Externí odkaz:
https://doaj.org/article/1bda826bfd8d4d7bb412f88323830e24
Autor:
Theodore M. Brasky, Roberta M. Ray, Alison M. Newton, Sandi L. Navarro, Jeannette M. Schenk, Holli A. Loomans-Kropp, Rhonda S. Arthur, Linda G. Snetselaar, John Hays, Marian L. Neuhouser
Publikováno v:
Nutrition and Cancer. 75:1103-1108
Autor:
Sameek Roychowdhury, Aharon G. Freud, John Hays, Kristen K. Ciombor, Dorrelyn M. Martin, Thuy Dao, Amy M. Smith, Eric Samorodnitsky, Jharna Miya, Michele R. Wing, Julie W. Reeser, Hui-Zi Chen, Kelly M. Bailey, Mikayla Dantuono, Hannah Barker, Max Wilberding, Alexandria Lenyo, Melanie A. Krook
Primer sequences used for PCR and Sanger sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42608d465fb41549fd11c1548623d69
https://doi.org/10.1158/1535-7163.22519083
https://doi.org/10.1158/1535-7163.22519083
Autor:
Sameek Roychowdhury, Julie W. Reeser, John Hays, Darshna Bhatt, Michele R. Wing, Eric Samorodnitsky, Elijah P. Gardner, Lianbo Yu, Jharna Miya, Cristina Ocrainiciuc, Hannah Parks, Senthilkumar Damodaran, Jharna Datta
Activation of FGFR signaling through mutations, amplifications, or fusions involving FGFR1, 2, 3, or 4 is seen in multiple tumors, including lung, bladder, and cholangiocarcinoma. Currently, several clinical trials are evaluating the role of novel FG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e21686828eb56109db6f049a67750f
https://doi.org/10.1158/1535-7163.c.6538800
https://doi.org/10.1158/1535-7163.c.6538800
Autor:
Sameek Roychowdhury, Aharon G. Freud, John Hays, Kristen K. Ciombor, Dorrelyn M. Martin, Thuy Dao, Amy M. Smith, Eric Samorodnitsky, Jharna Miya, Michele R. Wing, Julie W. Reeser, Hui-Zi Chen, Kelly M. Bailey, Mikayla Dantuono, Hannah Barker, Max Wilberding, Alexandria Lenyo, Melanie A. Krook
The fibroblast growth factor receptor (FGFR) signaling pathway is aberrantly activated in approximately 15% to 20% of patients with intrahepatic cholangiocarcinoma. Currently, several FGFR kinase inhibitors are being assessed in clinical trials for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5f6e892ef6a15aec83851e3e501d11
https://doi.org/10.1158/1535-7163.c.6542283.v1
https://doi.org/10.1158/1535-7163.c.6542283.v1
Autor:
Sameek Roychowdhury, Aharon G. Freud, John Hays, Kristen K. Ciombor, Dorrelyn M. Martin, Thuy Dao, Amy M. Smith, Eric Samorodnitsky, Jharna Miya, Michele R. Wing, Julie W. Reeser, Hui-Zi Chen, Kelly M. Bailey, Mikayla Dantuono, Hannah Barker, Max Wilberding, Alexandria Lenyo, Melanie A. Krook
Sequence for FGFR2-KIAA1598 fusion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee6583ef2a4168c8f00b172f486ec2b
https://doi.org/10.1158/1535-7163.22519089.v1
https://doi.org/10.1158/1535-7163.22519089.v1