Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John Hawse"'
Autor:
Shivani N Mann, Niran Hadad, Molly Nelson Holte, Alicia R Rothman, Roshini Sathiaseelan, Samim Ali Mondal, Martin-Paul Agbaga, Archana Unnikrishnan, Malayannan Subramaniam, John Hawse, Derek M Huffman, Willard M Freeman, Michael B Stout
Publikováno v:
eLife, Vol 9 (2020)
Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated by obesity. Dietary interventions can reverse metabolic declines and slow aging, although compliance issues remain paramount. 17α-estradiol treatment improves me
Externí odkaz:
https://doaj.org/article/1b1546f66bc7437c80062d0bfab7f142
Autor:
Mateusz Opyrchal, Jeffrey L Salisbury, Shuya Zhang, James McCubrey, John Hawse, Mattew P Goetz, Gwen A Lomberk, Tufia Haddad, Amy Degnim, Carol Lange, James N Ingle, Evanthia Galanis, Antonino B D'Assoro
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96995 (2014)
Development of endocrine resistance during tumor progression represents a major challenge in the management of estrogen receptor alpha (ERα) positive breast tumors and is an area under intense investigation. Although the underlying mechanisms are st
Externí odkaz:
https://doaj.org/article/c7da98dd6ce74f7c926be89deef9be93
Autor:
Sayantani Sarkar Bhattacharya, Taylor L. Witter, Anh T. Cong, Elizabeth S. Bruinsma, Swaathi Jayaraman, Matthew P. Goetz, John Hawse, Matthew Schellenberg
Publikováno v:
Cancer Research. 83:P2-24
Z-Endoxifen Allosterically Inhibits PKCβI and its Paradoxical Membrane Translocation Sayantani Sarkar Bhattacharya1, Taylor L. Witter1, Anh Q. T. Cong1, Elizabeth Bruinsma2, Swaathi Jayaraman2, Matthew P. Goetz2, John R. Hawse1, and Matthew J. Schel
Publikováno v:
Cancer Research. 83:P2-22
Background: Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related death among women worldwide. Triple-negative breast cancer (TNBC) is an aggressive subtype representing 15-20% of all breast cancers. TNBC often e
Autor:
Swaathi Jayaraman, Xinyan Wu, Krishna R. Kalari, Xiaojia Tang, Mary Kuffel, Elizabeth S. Bruinsma, Santosh Renuse, James N. Ingle, Joel Reid, Matthew Schellenberg, John Hawse, Akhilesh Pandey, Matthew P. Goetz
Publikováno v:
Cancer Research. 83:P3-11
Background: In phase I/II clinical trials, the tamoxifen metabolite Z-endoxifen (ENDX) demonstrated substantial oral bioavailability and promising antitumor activity in endocrine-refractory estrogen-receptor positive breast cancer (ER+ BC) and other
Autor:
Yoann Tatarenko, Philippe Pouletaut, Malayannan Subramaniam, Alexandra Josse, Théophile Cocquerez, John Hawse, Chatelin, S., Sabine Bensamoun
Publikováno v:
World Congress of Biomechanics
World Congress of Biomechanics, Jul 2022, Taipei, Taiwan
HAL
World Congress of Biomechanics, Jul 2022, Taipei, Taiwan
HAL
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3a0f05f526811d65838021df4e6678db
https://hal.science/hal-03882267
https://hal.science/hal-03882267
Autor:
Zhijun Guo, Jianxun Lei, Hrishi Venkatesh, David Owen, Adam Bass, Christine Cannon, Joshua McCarra, Brenda Koniar, Craig Flory, Beverly Norris, Robert J. Schumacher, Swaathi Jayaraman, John Hawse, Emmanuel S. Antonarakis, Emanuel F. Petricoin, Julia Wulfkuhle, Robert D. Cardiff, Elizabeth A. Ambrose, Gunda I. Georg, Kaylee L. Schwertfeger, Michael A. Farrar, Brad St. Croix, Matthew P. Goetz, David A. Potter
Publikováno v:
Cancer Research. 83:LB102-LB102
Introduction: Immune checkpoint blockade (ICB) has clinical activity in triple negative breast cancer (TNBC) but is less effective in the ER+HER2- signature, where there is a cold immune microenvironment (IM) and regulatory T cells (Tregs) may suppre
Autor:
Esther Rodman, Michael Emch, Elizabeth Bruinsma, Xiaonan Hou, Scott Kaufmann, Saravut J. Weroha, John Hawse
Publikováno v:
Cancer Research. 83:4862-4862
Ovarian cancer is the 7th most common cancer in women and the most fatal of all female reproductive cancers, with 5-year overall survival of 10-30%. Despite initial responses to first line platinum- and paclitaxel-based chemotherapies, >70% of ovaria
Publikováno v:
Cancer Research. 82:1129-1129
Ovarian cancer is the 7th most common cancer in women. It is the most fatal of all female reproductive cancers, due to the 5-year overall survival of 10-30% and over half of patients being diagnosed with late-stage disease. Despite initial response t
Autor:
Lydie Nadal-Desbarats, Malek Kammoun, Sandra Même, William Même, Frédéric Szeremeta, Malayannam Subramaniam, John Hawse, Sabine Bensamoun
Publikováno v:
11èmes journées scientifiques du réseau francophone de métabolomique et fluxomique (RFMF)
11èmes journées scientifiques du réseau francophone de métabolomique et fluxomique (RFMF), May 2018, Liège, Belgique. https://11-js-rfmf-2018.sciencesconf.org/data/p./Programme_11JSRFMF_2025.pdf
HAL
11èmes journées scientifiques du réseau francophone de métabolomique et fluxomique (RFMF), May 2018, Liège, Belgique. https://11-js-rfmf-2018.sciencesconf.org/data/p./Programme_11JSRFMF_2025.pdf
HAL
National audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::40942a9c5ffc4bd38018d888d855cfff
https://hal.utc.fr/hal-01982924
https://hal.utc.fr/hal-01982924