Zobrazeno 1 - 10
of 12
pro vyhledávání: '"John Harris Ward"'
Autor:
Anne C. Kirchhoff, Jordan P. McPherson, Anna C. Beck, Kathi Mooney, Richard Nelson, Lorinda A. Coombs, Karen Titchener, Brock O'Neil, Benjamin Haaland, John Harris Ward
Publikováno v:
J Clin Oncol
PURPOSE Patients with cancer experience high rates of morbidity and unplanned health care utilization and may benefit from new models of care. We evaluated an adult oncology hospital at home program's rate of unplanned hospitalizations and health car
Autor:
Kelli M. Thorne, John Harris Ward, Mary Brittain-Blankenship, Paul J. Shami, Sunil Sharma, Saundra S. Buys, Kenneth M. Boucher, Wallace Akerley, Kenneth Grossman, Ken M. Kosak, Kimberly McGregor, Neeraj Agarwal, Thomas P. Kennedy, Moises Terrazas, Theresa L. Werner, Kristen C. Kelley, Douglas W. Sborov, John R. Weis
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Cancer
BMC Cancer
BackgroundDisulfiram and metals inactivate key oncoproteins resulting in anti-neoplastic activity. The goal of this study was to determine the maximum tolerated dose of copper when administered with disulfiram in patients with advanced solid tumors a
Autor:
Karla V. Ballman, Kristen N. Ganjoo, Daniel A. Rushing, Richard F. Riedel, John Harris Ward, David A. Liebner, Warren Chow, Michael B. Livingston, Robert G. Maki, Lara E. Davis, Yao Lu, Denise K. Reinke, Steven Attia, Leo Mascarenhas, Elizabeth T. Loggers, Vicki L. Keedy, Jennifer Wright, Christopher W. Ryan, Damon R. Reed, Scott H. Okuno
Publikováno v:
The Oncologist
The oncologist, vol 25, iss 11
The oncologist, vol 25, iss 11
Trial Information Click here to access other published clinical trials. Lessons Learned The results from the liposarcoma cohort of SARC024 confirm previously published data and do not support the routine use of regorafenib in this patient population.
Autor:
John Harris Ward, Christina M. Wilson, Heidi Nielson, Kathi Mooney, Eli Iacob, Jennifer Lloyd
Publikováno v:
Journal of Clinical Oncology. 39:12000-12000
12000 Background: Unplanned health care utilization due to poorly controlled cancer symptoms is common and important to avoid during the Covid-19 pandemic. In a randomized trial we evaluated whether remote symptom monitoring and management utilizing
Autor:
Anna C. Beck, Lorinda A. Coombs, Karen Ameloot, Kathi Mooney, John Harris Ward, Shannon Shepherd, Karen Titchener, Kimberly Dumas
Publikováno v:
Journal of Clinical Oncology. 38:5-5
5 Background: Hospital at Home provides acute hospital level care to patients in their homes, diminishing the need for inpatient care or emergency department (ED) use. It has been evaluated for a variety of acute and chronic conditions but not in adu
Autor:
Jordan P. McPherson, John Harris Ward, Karen Ameloot, Benjamin Haaland, Richard E. Nelson, Karen Titchener, Lorinda A. Coombs, Anne C. Kirchhoff, Kathi Mooney, Anna C. Beck, Brock O Neil
Publikováno v:
Journal of Clinical Oncology. 38:7000-7000
7000 Background: Unplanned hospitalizations and emergency department (ED) visits are common during cancer care. Providing acute hospital level care at home may add value by decreasing hospital and ED use. We conducted the first evaluation of an oncol
Autor:
Nicholas N. Vahanian, Montaser Shaheen, Olivier Rixe, Yousef Zakharia, Charles J. Link, Eugene P. Kennedy, Mohammed M. Milhem, John Harris Ward, Joseph J. Drabick, David H. Munn, Robert R. McWilliams
Publikováno v:
Journal of Clinical Oncology. 36:9512-9512
9512Background: The indoleamine 2,3-dioxygenase (IDO) pathway is a key counter-regulatory mechanism that, in cancer, is exploited by tumors to prevent and evade anti-tumor immunity. Inhibitors of t...
Autor:
Christopher W. Ryan, Robert G. Maki, David A. Liebner, Lara E. Davis, Damon R. Reed, Kristen N. Ganjoo, John Harris Ward, Karla V. Ballman, Warren Chow, Richard F. Riedel, Michael B. Livingston, Denise K. Reinke, Elizabeth T. Loggers, Steven Attia, Leo Mascarenhas, Vicki L. Keedy, Jennifer Wright, Yao Lu, Daniel A. Rushing, Scott H. Okuno
Publikováno v:
Journal of Clinical Oncology. 36:11505-11505
11505Background: Pazopanib, a multi-targeted tyrosine kinase inhibitor, has shown activity in various soft tissue sarcomas. Activity in liposarcoma, however, is limited. Regorafenib is a multi-kina...
Autor:
John Harris Ward, John M. Kirkwood, Eric Whitman, Karl D. Lewis, David H. Lawson, Lee D. Cranmer, Joseph P. Catlett, Rene Gonzalez, Wolfram E. Samlowski
Publikováno v:
Investigational New Drugs. 29:161-166
Melanoma continues to be a major health problem with no effective therapy. Melanocytes, both benign and malignant, express many anti-apoptotic factors. Survivin is a member of the family of inhibitors of apoptosis proteins (IAP) and is preferentially
Autor:
Wallace Akerley, Mary Brittain Blankenship, Kenneth M. Boucher, John R. Weis, Saundra S. Buys, Moises Terrazas, Theresa L. Werner, Neeraj Agarwal, Sunil Sharma, Paul J. Shami, Ken M. Kosak, John Harris Ward, Kimberly Jones, Kenneth F. Grossmann
Publikováno v:
Cancer Research. 71:1308-1308
Background: Disulfiram inhibits hepatic aldehyde dehydrogenase causing accumulation of acetaldehyde when alcohol is ingested and is used to treat alcohol addiction. When metal ions such as copper are combined with disulfiram, key oncoproteins are bou