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Akademický článek
The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes
Autor: Keith Conrad Fernandez, Laura Feeney, Ryan M Smolkin, Wei-Feng Yen, Allysia J Matthews, William Alread, John HJ Petrini, Jayanta Chaudhuri
Publikováno v: eLife, Vol 11 (2022)
During the development of humoral immunity, activated B lymphocytes undergo vigorous proliferative, transcriptional, metabolic, and DNA remodeling activities; hence, their genomes are constantly exposed to an onslaught of genotoxic agents and process
Externí odkaz: https://doaj.org/article/c5a7957245bf45f98cfc381bda670cc8
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2
The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes
Autor: Laura Feeney, Keith Conrad Fernandez, Ryan M Smolkin, Wei-Feng Yen, Allysia J Matthews, William Alread, John HJ Petrini, Jayanta Chaudhuri
Publikováno v: eLife. 11
During the development of humoral immunity, activated B lymphocytes undergo vigorous proliferative, transcriptional, metabolic, and DNA remodeling activities; hence, their genomes are constantly exposed to an onslaught of genotoxic agents and process
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813b5bcefb91d737ffe596b90eb04282
https://doi.org/10.7554/elife.77073
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Plný text Recenzováno Digitální knihovna AV ČR
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