Zobrazeno 1 - 10
of 22
pro vyhledávání: '"John H. R. Winstanley"'
Autor:
Philip S. Rudland, Dong Liu Barraclough, Suzete de Silva Rudland, John H. R. Winstanley, Christopher R. West, Angela Platt-Higgins, Roger Barraclough
Publikováno v:
The American Journal of Pathology. 175:1848-1857
The secreted metastasis-inducing protein, human anterior gradient 2 (AGR2), has been independently reported to be associated with either a reduced or an increased survival of different groups of patients with breast cancer. We now aim to analyze the
Autor:
Chandeene Roshanlall, Joe Carroll, John H. R. Winstanley, Angela Platt-Higgins, Lee Martin, Roger Barraclough, Suzete de Silva Rudland, Philip S. Rudland, Christopher R. West, Sam Leinster
Publikováno v:
Clinical Cancer Research. 12:1192-1200
PURPOSE: S100A4 and the estrogen-inducible osteopontin are alone capable of inducing angiogenesis and metastasis in rodent models for breast cancer. The present study assesses the relationship of S100A4 and osteopontin with vessel density and estroge
Autor:
Philip S. Rudland, Joe Carroll, Roger Barraclough, John H. R. Winstanley, Angela Platt-Higgins, Suzete de Silva Rudland, Guozheng Wang
Publikováno v:
Cancer Research. 66:1199-1207
S100P, an EF-hand calcium-binding protein, has been reported to be associated with the progression of many types of cancers. Transfection of an expression vector for S100P into a benign, nonmetastatic rat mammary cell line causes a 4- to 6-fold incre
Autor:
C. Renshaw, Roger Barraclough, Suzete de Silva Rudland, John H. R. Winstanley, Angela Platt-Higgins, Philip S. Rudland, Christopher R. West
Publikováno v:
International Journal of Cancer. 89:198-208
Our aim was to compare the occurrence and prognostic significance over 14-20 years of immunocytochemically detected S100A4 and other tumour variables in primary tumours from 349 patients with operable breast cancer. For a cut-off of 1% staining of th
Autor:
Philip S. Rudland, Angela Platt-Higgins, Shanez Y. Anandappa, Roger Barraclough, Ross Sibson, John H. R. Winstanley
Publikováno v:
International Journal of Cancer. 88:209-216
A panel of human breast cancer specimens was examined for single base change mutations by DNA sequencing and for larger deletions using a PCR-based assay. In the cancer specimens examined, no sequencing variants were detected other than a previously
Publikováno v:
International Journal of Cancer. 76:459-463
The cell-surface receptor tyrosine kinase protein c-erbB-2 is immunocytochemically detected as membrane staining on the surface of cancer cells in 20-30% of cases of breast cancer, and its presence has been associated with poor prognosis for the pati
Autor:
B. Green, Philip S. Rudland, C. Renshaw, L. Martin, Derek Lowe, Sam Leinster, John H. R. Winstanley
Publikováno v:
British Journal of Cancer
The intensity of angiogenesis as measured by the density of microvessels has been reported to be associated with a poor prognosis in invasive breast cancer in some, but not all, studies. The reasons for these discrepancies may be variations in the me
Publikováno v:
British Journal of Cancer
The assessment of a tumour's angiogenic potential, by measuring the microvessel density in histological sections, assumes that a 4-microm section is representative of whole tumour vascularity. This study has examined this assumption by comparing the
Autor:
Angela Platt-Higgins, Roger Barraclough, Christopher R. West, Suzete de Silva Rudland, Philip S. Rudland, Nigel J. Jones, John H. R. Winstanley, Joseph Carroll
Two subgroups of invasive breast carcinomas have been identified with a poor prognosis in different patient cohorts: the basal-like category and the subgroup containing proteins capable of inducing metastasis in experimental rodents, the metastasis-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c699c3a0a42b565a37cf0bf8465c0f
https://europepmc.org/articles/PMC3157230/
https://europepmc.org/articles/PMC3157230/
Publikováno v:
Journal of Histochemistry & Cytochemistry. 41:543-553
We performed immunocytochemical staining of benign, in situ, and malignant breast disease to identify antigens related to the presence of the major parenchymal cell types of the normal breast. Markers for the epithelial cells, antiserum to epithelial