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pro vyhledávání: '"John H. Peever"'
Publikováno v:
SLEEP.
Research into sleep–wake behaviors relies on scoring sleep states, normally done by manual inspection of electroencephalogram (EEG) and electromyogram (EMG) recordings. This is a highly time-consuming process prone to inter-rater variability. When
Publikováno v:
Current Biology. 33:1550-1564.e5
Publikováno v:
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
Narcolepsy is a sleep disorder manifesting symptoms such as excessive daytime sleepiness and often cataplexy, a sudden and involuntary loss of muscle activity during wakefulness. The underlying neuropathological basis of narcolepsy is the loss of ore
Publikováno v:
Current biology : CB. 31(7)
Despite intensive research efforts, biologists still do not have a clear picture of the brain circuitry that controls behavioural arousal. However, new research has identified a novel septo-hypothalamic circuit that functions to promote wakefulness.
Autor:
John H. Peever, HanHee Lee
Publikováno v:
Curr Biol
The ability to rapidly arouse from sleep is important for survival. However, increased arousals in patients with sleep apnea and other disorders prevent restful sleep, and contribute to cognitive, metabolic and physiologic dysfunction [1, 2]. Little
Publikováno v:
Sleep. 44:A2-A3
Introduction Narcolepsy is a neurological disorder that is characterized by the loss of orexin neurons in the lateral hypothalamus. Cataplexy is a symptom of narcolepsy and is identified by a sudden loss of muscle tone during wakefulness. Cataplexy a
Autor:
Richard L. Horner, John H. Peever
Publikováno v:
CONTINUUM: Lifelong Learning in Neurology. 23:955-972
This article outlines the fundamental brain mechanisms that control sleep-wake patterns and reviews how pathologic changes in these control mechanisms contribute to common sleep disorders.Discrete but interconnected clusters of cells located within t
Autor:
John H. Peever, Dillon McKenna
Publikováno v:
Movement Disorders. 32:636-644
During healthy rapid eye movement sleep, skeletal muscles are actively forced into a state of motor paralysis. However, in rapid eye movement sleep behavior disorder-a relatively common neurological disorder-this natural process is lost. A lack of mo
Publikováno v:
Sleep Medicine. 64:S302-S303
Autor:
John H. Peever
Publikováno v:
Current Biology. 28:R800-R802
Skin and body warming help initiate sleep, but the underlying neural mechanisms remain unclear. New research in mice shows that skin warming recruits a previously unidentified hypothalamic circuit that functions to promote sleep and body cooling.