Zobrazeno 1 - 10
of 126
pro vyhledávání: '"John H. Mennear"'
Autor:
Kjellstrom, Tord
Publikováno v:
The Quarterly Review of Biology, 1980 Mar 01. 55(1), 109-109.
Externí odkaz:
https://www.jstor.org/stable/2826186
Autor:
Kerry T. Blanchard, Sylvia M. Furst, John H. Mennear, James H. Stoltz, J. B. Majeska, P. D. Lilly, R. E. Stoll
Publikováno v:
Toxicological Sciences. 90:440-450
Phenolphthalein (800 and 2400 mg/kg/day by gavage and 2400 mg/kg/day by diet) and bisacodyl (800-500, 4000-2000, and 8000 mg/kg/day by gavage) were administered to 15 male and 15 female and 20 male and 20 female p53(+/-) mice respectively for 26 week
Publikováno v:
International Journal of Toxicology. 24:107-113
The objective of this study was to assess the mutagenic potential of a synthesized tripeptide, L-valyl-L-prolyl-L-proline (VPP), to induce mutational changes in Salmonella typhimurium LT2 strains TA1535, TA1537, TA98, and TA100, and Escherichia coli
Publikováno v:
International Journal of Toxicology. 24:61-89
The objective of these studies was to assess the effects of the tripeptides, L-valyl-L-prolyl-L-proline (VPP) and L-isoleucyl-L-prolyl-L-proline (IPP), on reproductive capabilities of male and female rats. The specific goals of the experiments were (
Publikováno v:
International Journal of Toxicology. 24:25-39
The objective of these repeated-dose, 8-week studies was to assess the toxicological potential of a synthetic tripeptide, L-valyl-L-prolyl-L-proline (VPP), when administered to Charles River rats and Beagle dogs. Groups of 20 male and 20 female rats
Publikováno v:
International Journal of Toxicology. 24:41-59
The objective of this multiple-dose toxicity study was to assess the toxicological potential of two tripeptides, L-valyl-L-prolyl-L-proline (VPP) and L-isoleucyl-L-prolyl-L-proline (IPP), when administered once daily for 91 consecutive days to rats.
Publikováno v:
Journal of Immunotoxicology. 2:85-96
Results from earlier experiments in our laboratories revealed that both selective and nonselective inhibitors of cyclooxygenase-2 possess little potential for decreasing in vitro phagocytosis by rat macrophages or canine neutrophils and no potential
Autor:
Ray W. Tennant, Ray E. Stoll, Joel F. Mahler, Judson W. Spalding, William C. Eastin, Robert L. Binder, Dan G. Branstetter, Bruce Mccullough, John H. Mennear, John R. Bucher
Publikováno v:
Toxicologic Pathology. 29:60-80
In a Government/Industry/Academic partnership to evaluate alternative approaches to carcinogenicity testing, 21 pharmaceutical agents representing a variety of chemical and pharmacological classes and possessing known human and or rodent carcinogenic
Autor:
Judson W. Spalding, Raymond W. Tennant, Stanley Stasiewicz, John H. Mennear, William C. Eastin
Publikováno v:
Toxicologic Pathology. 29:51-59
The Tg.AC (v-Ha-ras) transgenic mouse model provides a reporter phenotype of skin papillomas in response to either genotoxic or nongenotoxic carcinogens. In common with the conventional bioassay, the Tg.AC model responds to known human carcinogens an
Autor:
John H. Mennear
Publikováno v:
Regulatory Toxicology and Pharmacology. 27:265-272