Výsledky vyhledávání - "John H. Klippel"

Measuring quality in arthritis care: Methods for developing the Arthritis Foundation's quality indicator set

Autor: Daniel H. Solomon, John H. Klippel, Sally C. Morton, Kenneth G. Saag, Sarah Sampsel, Catherine H. MacLean

Publikováno v: Arthritis Care & Research. 51:193-202

Objective To develop a comprehensive set of explicit process measures to assess the quality of health care for osteoarthritis, rheumatoid arthritis, and analgesics use. Methods Potential quality measures and a summary of existing data to support or r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ed0f3e5a7ba0d562c0b944a46109dd2
https://doi.org/10.1002/art.20248

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Transfusion-associated GVHD after fludarabine therapy in a patient with systemic lupus erythematosus

Autor: John F. Tisdale, Charles D. Bolan, Mark A. Popovsky, Dimitrios T. Boumpas, Susan F. Leitman, James E. Balow, John H. Klippel, Gabor G. Illei

Publikováno v: Transfusion. 43:1667-1671

BACKGROUND: Fludarabine, a purine antimetabolite with potent immunosuppressive properties, has previously been associated with the development of transfusion-associated GVHD (TA-GVHD) in patients with hematologic malignancies. Its role as a risk fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d911a450aaceee2d782d996abe69184
https://doi.org/10.1046/j.0041-1132.2003.00579.x

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UPDATE ON CYCLOPHOSPHAMIDE FOR SYSTEMIC LUPUS ERYTHEMATOSUS

Autor: Robert A. Ortmann, John H. Klippel

Publikováno v: Rheumatic Disease Clinics of North America. 26:363-375

Over the past decade cyclophosphamide has come to assume an increasingly prominent role in the management of severe, life-threatening manifestations of SLE. Intermittent, intravenous pulse cyclophosphamide has become the standard of treatment of diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422b93c153dda593f2c9048a012bf073
https://doi.org/10.1016/s0889-857x(05)70143-5

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Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis

Autor: Raphaela Goldbach-Mansky, Paul H. Duray, Joseph M. Hoxworth, John H. Klippel, Cheryl Yarboro, David E. Kleiner, Hani El-Gabalawy, David L. Smith, H. Ralph Schumacher, Jennifer M. Lee

Publikováno v: Arthritis Research

Serum and synovial tissue expression of the matrix metalloproteinase (MMP)-2 and -9 and their molecular regulators, MMP-14 and TIMP-2 was examined in 28 patients with inflammatory early synovitis and 4 healthy volunteers and correlated with the prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfaea40af3475f9ec2bc5003ed6c21d
http://europepmc.org/articles/PMC17808

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Association of HLA alleles and clinical features in patients with synovitis of recent onset

Autor: John H. Klippel, Cheryl Yarboro, Ronald L. Wilder, David L. Smith, Raphaela Goldbach-Mansky, Hani El-Gabalawy, Sherri J. Bale, H. Ralph Schumacher, Thurraya Arayssi, Pércio S. Gulko

Publikováno v: Arthritis & Rheumatism. 42:1696-1705

Objective To determine how HLA alleles are associated with the clinical disease patterns of patients with synovitis of recent onset. Methods The HLA alleles A, B, C, DRβ1, and DQβ1 were determined in a cohort of 211 patients (mean age 42 years, 64%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c047f95d3e99b8a8522c1bb4725e874
https://doi.org/10.1002/1529-0131(199908)42:8<1696::aid-anr19>3.0.co

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Chlamydia trachomatis nucleic acids can be found in the synovium of some asymptomatic subjects

Autor: Alan P. Hudson, H. Ralph Schumacher, Jennifer Lee, Marianna Crane, Thurayya Arayssi, Herve Gerard, John H. Klippel

Publikováno v: Arthritis & Rheumatism. 42:1281-1284

Objective The recent identification of antigens or nucleic acids of infectious agents in the joints of patients with reactive arthritis has raised questions about whether chlamydial or other infectious agent nucleic acids are also present in normal j

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cdff36b3cbd6eab4c46642c756286f8
https://doi.org/10.1002/1529-0131(199906)42:6<1281::aid-anr27>3.0.co

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Gamma Interferon and Interleukin-10 Gene Expression in Synovial Tissues from Patients with Early Stages of Chlamydia -Associated Arthritis and Undifferentiated Oligoarthritis and from Healthy Volunteers

Autor: Alan P. Hudson, Hervé C. Gérard, Patrick J. Branigan, Thurayya Arayssi, H. Ralph Schumacher, Shigeru Kotake, John H. Klippel, Cheryl Yarboro, Ronald L. Wilder

Publikováno v: Infection and Immunity. 67:2682-2686

Genetically determined differences in interleukin-10 (IL-10) and gamma interferon (IFN-γ) responses in mice correlate with clearance of Chlamydia pneumonitis infection. We measured the synovial expression of IL-10 and IFN-γ and additional cytokine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7ca812411033556dd60285c4b3b16f
https://doi.org/10.1128/iai.67.5.2682-2686.1999

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8 Indications for, and use of, cytotoxic agents in SLE

Autor: John H. Klippel

Publikováno v: Baillière's Clinical Rheumatology. 12:511-527

Over the past decade, cytotoxic drugs have come to assume an increasingly important role in the management of systemic lupus erythematosus. Intravenous cyclophosphamide has become the standard treatment for lupus affecting major organs, in particular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3750a8691549d85de4aca8d89f83924
https://doi.org/10.1016/s0950-3579(98)80033-2

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Second-Line Drug Therapy for Rheumatoid Arthritis

Autor: Alastair J.J. Wood, Joseph M. Cash, John H. Klippel

Publikováno v: New England Journal of Medicine. 330:1368-1375

Three major classes of drugs are used in the treatment of patients with rheumatoid arthritis: nonsteroidal antiinflammatory drugs, corticosteroids, and drugs that are thought to modify fundamental pathologic processes responsible for the chronic infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0417423140e4a7ff5f4310288b52a14e
https://doi.org/10.1056/nejm199405123301908

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