Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John H. Kimbrough"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT This study reports the activity of cefiderocol against Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. isolates collected from the United States and Europe, including Israel and Turkey, from 2020 to 2021. Among Enterobactera
Externí odkaz:
https://doaj.org/article/765cb9d27be34b02b8cbe9c652e4ce3f
Autor:
Lindsay R. Grant, Kevin Apodaca, Lalitagauri Deshpande, John H. Kimbrough, Kyla Hayford, Qi Yan, Rodrigo Mendes, Alejandro Cané, Bradford D. Gessner, Adriano Arguedas
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionPneumococcal conjugate vaccines (PCVs), including higher valency vaccines such as PCV20, have the potential to reduce pediatric otitis media. We assessed serotype distribution, potential PCV coverage, and antimicrobial susceptibility of S
Externí odkaz:
https://doaj.org/article/fe75c8964f5b4993bea3ea7db5e95ed8
Publikováno v:
Antibiotics, Vol 13, Iss 6, p 564 (2024)
We evaluated the activities of aztreonam/avibactam and recently approved β-lactamase inhibitor combinations (BLICs) to compare the antimicrobial susceptibility patterns of Enterobacterales and Pseudomonas aeruginosa isolated from intensive care unit
Externí odkaz:
https://doaj.org/article/08871ef02f3243d7b65bcb044824b4f6
Publikováno v:
JAC-Antimicrobial Resistance. 5
BackgroundAztreonam/avibactam is under development to treat infections caused by Gram-negative bacteria. We evaluated the in vitro activities of aztreonam/avibactam and comparators against a global collection of carbapenem-resistant Enterobacterales
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a13519a7660312918a2531d94044148
https://doi.org/10.1093/jacamr/dlad032
https://doi.org/10.1093/jacamr/dlad032
Publikováno v:
Open Forum Infectious Diseases. 10
BackgroundThe Clinical and Laboratory Standards Institute (CLSI) lowered the Enterobacterales-susceptible/-resistant breakpoints for amikacin in 2023 from ≤16/≥64 mg/L to ≤4/≥16 mg/L and the breakpoints for gentamicin and tobramycin from ≤4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a59ed65960e121e858163eef7a97fd1
https://doi.org/10.1093/ofid/ofad058
https://doi.org/10.1093/ofid/ofad058
Publikováno v:
Open Forum Infectious Diseases. 10
BackgroundAs the frequency of metallo-β-lactamase (MBL)-producing Enterobacterales is increasing worldwide, effective antimicrobials to treat the infections caused by these organisms are urgently needed.MethodsThe activity of aztreonam-avibactam and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54620913107810ee691a5d5ebc372e3a
https://doi.org/10.1093/ofid/ofad046
https://doi.org/10.1093/ofid/ofad046
Publikováno v:
Open Forum Infectious Diseases. 10
BackgroundThe temporal and longitudinal trends of β-lactamases and their associated susceptibility patterns were analyzed for Escherichia coli and Klebsiella pneumoniae isolates consecutively collected in 56 United States hospitals during 2016–202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d5ed975c4f1b72e9ddfc5ab1e7408c
https://doi.org/10.1093/ofid/ofad038
https://doi.org/10.1093/ofid/ofad038
Autor:
Rodrigo E Mendes, S J Ryan Arends, John H Kimbrough, Valerie Kantro, Deborah Butler, Nicole E Scangarella-Oman, Jennifer M Streit, Mariana Castanheira
Publikováno v:
Open Forum Infectious Diseases. 9
Background Gepotidacin is a novel first in class triazaacenaphthylene antibiotic in Phase 3 clinical trials for the treatment of gonorrhea and uncomplicated urinary tract infection (UTI). This study evaluates the epidemiology of E. coli (EC) causing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2df17f1dfea2a34e5cfa0af5ceee163f
https://doi.org/10.1093/ofid/ofac492.693
https://doi.org/10.1093/ofid/ofac492.693
Autor:
Rodrigo E Mendes, John H Kimbrough, Valerie Kantro, Dee Shortridge, Helio S Sader, Jennifer M Streit, Mariana Castanheira
Publikováno v:
Open Forum Infectious Diseases. 9
Background Cefiderocol (CFDC) is a siderophore cephalosporin that hijacks the Gram-negative bacteria iron transport system to facilitate cell entry and reach its target. CFDC remains stable to hydrolysis in the presence of serine β-lactamases (ESBLs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c5e6e3bd8226fa541bc41ad744c92e
https://doi.org/10.1093/ofid/ofac492.694
https://doi.org/10.1093/ofid/ofac492.694
Autor:
Nicole E. Smalley, Ajai A. Dandekar, Rhea G. Abisado, Josephine R. Chandler, John H. Kimbrough, Vaughn D. Craddock, Brielle M. Mckee
Publikováno v:
Appl Environ Microbiol
The Pseudomonas aeruginosa LasR-LasI (LasR-I) quorum sensing system regulates secreted proteases that can be exploited by cheaters, such as quorum sensing receptor-defective (lasR) mutants. lasR mutants emerge in populations growing on casein as a so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98354d3f651d947191af06603eb1c2e6
https://doi.org/10.1128/aem.00029-21
https://doi.org/10.1128/aem.00029-21