Zobrazeno 1 - 10
of 301
pro vyhledávání: '"John H. Kersey"'
Autor:
John H. Kersey, Weili Chen, Qing Yao, Terence H. Rabbitts, Wendy A. Hudson, Marnie Taylor, Jennifer J. Johnson
The steps to leukemia following an in utero fusion ofMLL (HRX, ALL-1) to a partner gene in humans are not known. Introduction of the Mll-AF9 fusion gene into embryonic stem cells results in leukemia in mice with cell-type specificity similar to human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ea79bf3a446f437fd0b61f76b2825b
https://doi.org/10.1182/blood-2002-05-1515
https://doi.org/10.1182/blood-2002-05-1515
Autor:
Samuel Jay Pirruccello, J. M. Greenberg, C. W. Wilkowski, Frank Griesinger, Rogelio González-Sarmiento, John H. Kersey
Publikováno v:
Leukemialymphoma. 3(2)
The gamma gene product is a component of the second T-cell receptor. We report a new case of acute lymphoblastic leukemia bearing a CD3+ CD4- CD5+ CD7+ CD8- WT31- immunophenpotype that expresses the gamma peptide. Immunoprecipitation studies using an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc76251674ade6fcd16cd01d50aea30
https://pubmed.ncbi.nlm.nih.gov/27457301
https://pubmed.ncbi.nlm.nih.gov/27457301
Autor:
John H. Kersey, H. Berna Beverloo, Ruud Delwel, Scott A. Armstrong, Eric M.J. Bindels, Claudia Erpelinck, Hartmut Döhner, Elwin J. C. Rombouts, Sanne Lugthart, Jurgen R. Haanstra, Erdogan Taskesen, Andrei V. Krivtsov, Wendy A. Hudson, Ashish R. Kumar, Elizabeth Wocjtowicz, Marije Havermans
Publikováno v:
Blood, 119(24), 5838-5849. American Society of Hematology
The proto-oncogene EVI1 (ecotropic viral integration site-1), located on chromosome band 3q26, is aberrantly expressed in human acute myeloid leukemia (AML) with 3q26 rearrangements. In the current study, we showed, in a large AML cohort carrying 11q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a63abc29f7a8c4cdd3622db5773d127
https://doi.org/10.1182/blood-2011-11-393827
https://doi.org/10.1182/blood-2011-11-393827
Autor:
Amy R. Rappaport, Aaron L. Sarver, Lara S. Collier, John H. Kersey, Raha A. Been, David J. Adams, Danhua Fan, Linda Wolff, Scott C. Kogan, David A. Largaespada, Johannes Zuber, Anne Francoise Lamblin, Sanne Lugthart, M. Gerard O'Sullivan, Kevin A. T. Silverstein, Ruud Delwel, Scott W. Lowe, Molly J. Nixon, Miechaleen D. Diers, Rachel J. Bergerson
Publikováno v:
Blood, 119(19), 4512-4523. American Society of Hematology
Patients with a t(9;11) translocation (MLL-AF9) develop acute myeloid leukemia (AML), and while in mice the expression of this fusion oncogene also results in the development of myeloid leukemia, it is with long latency. To identify mutations that co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fa279a9702167db6e5fe73283b63d5
https://doi.org/10.1182/blood-2010-04-281428
https://doi.org/10.1182/blood-2010-04-281428
Autor:
Kimberly J. Johnson, Gregory H. Reaman, Amy M. Linabery, Julie A. Ross, John H. Kersey, Stella M. Davies, Thien N. Sam, Joanne M. Hilden, Nyla A. Heerema
Publikováno v:
Pediatric Blood & Cancer. 58:836-839
Background Infant leukemias have a high frequency of mixed lineage leukemia (MLL) gene rearrangements.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00577ead81b32da9792fb3bbf790e5c
https://doi.org/10.1002/pbc.23274
https://doi.org/10.1002/pbc.23274
Publikováno v:
Leukemia Research. 35:305-309
The most frequent MLL-gene rearrangement found in leukemia is a reciprocal translocation with AF4 on chromosome 4 resulting in the formation of the MLL-AF4 and the AF4-MLL fusion genes. The oncogenic role of MLL-AF4 is documented but the significance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40fd1662e653a671d0509e633144d20
https://doi.org/10.1016/j.leukres.2010.08.011
https://doi.org/10.1016/j.leukres.2010.08.011
Autor:
Linda J. Burns, Claudio G. Brunstein, Mukta Arora, John H. Kersey, Bruce R. Blazar, Kathryn E. Dusenbery, Michael R. Verneris, Marcie Tomblyn, Paul J. Orchard, Margaret L. MacMillan, Dan S. Kaufman, Jeffrey S. Miller, Arne Slungaard, Philip B. McGlave, John E. Wagner, K. Scott Baker, Daniel J. Weisdorf, Todd E. DeFor, M. Tomblyn, Gregory M. Vercellotti
Publikováno v:
Journal of Clinical Oncology. 27:3634-3641
Purpose Analysis of hematopoietic cell transplantation (HCT) for high-risk or recurrent acute lymphoblastic leukemia (ALL) using different donor sources is confounded by variable conditioning and supportive care. Patients and Methods We studied 623 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fac9b385e39006e08e639e8dfe0231
https://doi.org/10.1200/jco.2008.20.2960
https://doi.org/10.1200/jco.2008.20.2960
Autor:
John H. Kersey, Harriet Noreen, Leonard J. Greenberg, Eloise R. Giblett, Nancy L. Reinsmoen, Peter S. Friend
Publikováno v:
Tissue Antigens. 13:19-34
Complete HLA typing including HLA--A, --B, --C, --DR (D related B cell typing), --D, mixed lymphocyte culture (MLC), and primed lymphocyte testing (PLT), together with complete red blood cell (RBC), glyoxalase (GLO), GBG (Factor B), and phosphoglucom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8219f39add52f2bc42cf83f57896e5
https://doi.org/10.1111/j.1399-0039.1979.tb01133.x
https://doi.org/10.1111/j.1399-0039.1979.tb01133.x
Publikováno v:
Clinical Genetics. 9:583-587
Three patients with Fanconi's anemia were analyzed for chromosome breaks. T and B cells were separated and grown in tissue culture with PHA and pokeweed antigen to ascertain the rates of breakage in these lymphocytic subpopulations. It has been found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac709b1561153e12ed872f290c40d648
https://doi.org/10.1111/j.1399-0004.1976.tb01616.x
https://doi.org/10.1111/j.1399-0004.1976.tb01616.x
Autor:
Joel M. Reid, Peter C. Adamson, Rochelle Bagatell, Susan M. Blaney, Stephanie L. Safgren, Mark Krailo, Richard J. Gilbertson, John H. Kersey, S. Percy Ivy, Ashish M. Ingle, Matthew M. Ames, Joseph P. Neglia, Luke Whitesell, Brenda J. Weigel
Publikováno v:
Clinical Cancer Research. 13:1789-1793
Purpose: To determine the recommended phase 2 dose, dose-limiting toxicities (DLT), pharmacokinetic profile, and pharmacodynamics of the heat shock protein (Hsp) 90 inhibitor, 17-allylaminogeldanamycin (17-AAG). Experimental Design: 17-AAG was admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6819f51fdbe0ffad1e84e3dd788ff4a
https://doi.org/10.1158/1078-0432.ccr-06-2270
https://doi.org/10.1158/1078-0432.ccr-06-2270