Zobrazeno 1 - 10
of 60
pro vyhledávání: '"John H. Hipwell"'
Autor:
Peter A Wijeratne, John H Hipwell, David J Hawkes, Triantafyllos Stylianopoulos, Vasileios Vavourakis
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184511 (2017)
We present an in-silico model of avascular poroelastic tumour growth coupled with a multiscale biphasic description of the tumour-host environment. The model is specified to in-vitro data, facilitating biophysically realistic simulations of tumour sp
Externí odkaz:
https://doaj.org/article/8926bc3ca3e5410fa3f2a3cb70894d5c
Autor:
Vasileios Vavourakis, Bjoern Eiben, John H Hipwell, Norman R Williams, Mo Keshtgar, David J Hawkes
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159766 (2016)
Surgical treatment for early-stage breast carcinoma primarily necessitates breast conserving therapy (BCT), where the tumour is removed while preserving the breast shape. To date, there have been very few attempts to develop accurate and efficient co
Externí odkaz:
https://doaj.org/article/ce5472b100da4ec28cefae0bc854c55e
Autor:
John H. Hipwell, Jeffrey M P Holly, Rachel Denholm, Elizabeth Folkerd, Isabel dos-Santos-Silva, Bianca De Stavola, Simon J. Doran, Martin O. Leach, David J. Hawkes, Mitch Dowsett
Publikováno v:
Denholm, R, De Stavola, B L, Hipwell, J H, Doran, S J, Holly, J M P, Folkerd, E, Dowsett, M, Leach, M O, Hawkes, D J & Dos-Santos-Silva, I 2018, ' Circulating growth and sex hormone levels and breast tissue composition in young nulliparous women ', Cancer Epidemiology, Biomarkers and Prevention, vol. 27, no. 12, pp. 1500-1508 . https://doi.org/10.1158/1055-9965.EPI-18-0036
Background: Endogenous hormones are associated with breast cancer risk, but little is known about their role on breast tissue composition, a strong risk predictor. This study aims to investigate the relationship between growth and sex hormone levels
Autor:
Thomas Buelow, David J. Hawkes, Sven Kabus, Thomy Mertzanidou, Björn Eiben, Vasileios Vavourakis, Cristian Lorenz, Norman R. Williams, Mohammed Keshtgar, John H. Hipwell, Sara Reis
Publikováno v:
Annals of Biomedical Engineering
Prone-to-supine breast image registration has potential application in the fields of surgical and radiotherapy planning, image guided interventions, and multi-modal cancer diagnosis, staging, and therapy response prediction. However, breast image reg
Autor:
Marta Cecilia Busana, David J. Hawkes, Simon J. Doran, John H. Hipwell, Bianca De Stavola, Isabel dos-Santos-Silva, Martin O. Leach, Rachel Denholm
Publikováno v:
Denholm, R, De Stavola, B, Hipwell, J H, Doran, S J, Busana, M C, Leach, M O, Hawkes, D J & Dos-Santos-Silva, I 2018, ' Growth Trajectories, Breast Size, and Breast-Tissue Composition in a British Pre-Birth Cohort of Young Women ', American Journal of Epidemiology, vol. 187, no. 6, kwx358, pp. 1259-1268 . https://doi.org/10.1093/aje/kwx358
Mammographic percent density, the proportion of fibroglandular tissue in the breast, is a strong risk factor for breast cancer, but its determinants in young women are unknown. We examined associations of magnetic resonance imaging (MRI) breast-tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcf89c09bd9c7eb9ff984796f7c304f
https://research-information.bris.ac.uk/ws/files/178487090/msy125.pdf
https://research-information.bris.ac.uk/ws/files/178487090/msy125.pdf
Autor:
Björn Eiben, Isabel dos Santos Silva, Simon J. Doran, Rachel Denholm, Marta Cecilia Busana, John H. Hipwell, Martin O. Leach, David J. Hawkes
Publikováno v:
Doran, S J, Hipwell, J H, Denholm, R, Eiben, B, Busana, M, Hawkes, D J, Leach, M O & Dos Santos Silva, I 2017, ' Breast MRI segmentation for density estimation : Do different methods give the same results and how much do differences matter? ', Medical Physics, vol. 44, no. 9, pp. 4573-4592 . https://doi.org/10.1002/mp.12320
Medical Physics
Medical Physics
Purpose: To compare two methods of automatic breast segmentation with each other and with manual segmentation in a large subject cohort. To discuss the factors involved in selecting the most appropriate algorithm for automatic segmentation and, in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00424532e9d39eed4163a0c916d4d581
https://research-information.bris.ac.uk/ws/files/147705520/Denholm2017_Medical_Physics.pdf
https://research-information.bris.ac.uk/ws/files/147705520/Denholm2017_Medical_Physics.pdf
Autor:
Beata Peplonska, Farhana Fadzli, Ana Pereira, Caroline Dickens, Eunjung Lee, Jisun Kim, Joachim Schüz, John L. Hopper, Sudhir Vinayak, Soo Hwang Teo, Jennifer Stone, Marina Pollán, Rulla M. Tamimi, Shivaani Mariapun, Ruy Lopez-Ridaura, Celine M. Vachon, Linda Linton, Mikael Hartman, Carla H. van Gils, Rose Ndumia, Mehri Sirous, Norman F. Boyd, Vahit Ozmen, Mustafa Erkin Aribal, Anya Burton, Giske Ursin, María Luisa Garmendia, Jong Won Lee, Gertraud Maskarinec, Reza Sirous, Chisato Nagata, Kee Seng Chia, Megan S. Rice, John H. Hipwell, Valerie McCormack, Sarah Vinnicombe, Martin Lajous, Hui Miao, Rasha Kamal, Ava Kwong, Anath Arzee Flugelman, Sue Moss, Agnieszka Bukowska, Graham G. Giles, Steve Allen, Christopher G. Scott, Anna M. Chiarelli, Samera Azeem Qureshi, Huiyan Ma, Johanna O. P. Wanders, Kimberly A. Bertrand, Isabel dos-Santos-Silva, Beatriz Pérez-Gómez, Dorria Salem
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
PLoS Medicine, Vol 14, Iss 6, p e1002335 (2017)
PLoS Medicine, 14(6). Public Library of Science
PLoS Medicine
Instituto de Salud Carlos III (ISCIII)
PLoS Medicine, Vol 14, Iss 6, p e1002335 (2017)
PLoS Medicine, 14(6). Public Library of Science
PLoS Medicine
Background Mammographic density (MD) is one of the strongest breast cancer risk factors. Its age-related characteristics have been studied in women in western countries, but whether these associations apply to women worldwide is not known. Methods an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e1cb4e0b96a6eaca8f83a2f3e7d927
Autor:
Sara, Reis, Patrycja, Gazinska, John H, Hipwell, Thomy, Mertzanidou, Kalnisha, Naidoo, Norman, Williams, Sarah, Pinder, David J, Hawkes
Publikováno v:
IEEE transactions on bio-medical engineering. 64(10)
The tumor microenvironment plays a crucial role in regulating tumor progression by a number of different mechanisms, in particular, the remodeling of collagen fibers in tumor-associated stroma, which has been reported to be related to patient surviva
Autor:
Amanda Eng, Mona Jeffreys, John H. Hipwell, Martin O. Leach, Isabel dos Santos Silva, David J. Hawkes, Rachel Denholm, Bianca De Stavola, Marta Cecilia Busana, Simon J. Doran
Publikováno v:
Breast Cancer Research : BCR
Denholm, R, De Stavola, B, Hipwell, J H, Doran, S J, Busana, M C, Eng, A, Jeffreys, M, Leach, M O, Hawkes, D & dos Santos Silva, I 2016, ' Pre-natal exposures and breast tissue composition : Findings from a British pre-birth cohort of young women and a systematic review ', Breast Cancer Research, vol. 18, 102 . https://doi.org/10.1186/s13058-016-0751-z
Denholm, R, De Stavola, B, Hipwell, J H, Doran, S J, Busana, M C, Eng, A, Jeffreys, M, Leach, M O, Hawkes, D & dos Santos Silva, I 2016, ' Pre-natal exposures and breast tissue composition : Findings from a British pre-birth cohort of young women and a systematic review ', Breast Cancer Research, vol. 18, 102 . https://doi.org/10.1186/s13058-016-0751-z
Background Breast density, the amount of fibroglandular tissue in the adult breast for a women’s age and body mass index, is a strong biomarker of susceptibility to breast cancer, which may, like breast cancer risk itself, be influenced by events e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2165914fe5fc972b8fb847415c55722a
https://researchonline.lshtm.ac.uk/id/eprint/2965168/1/art%3A10.1186%2Fs13058-016-0751-z.pdf
https://researchonline.lshtm.ac.uk/id/eprint/2965168/1/art%3A10.1186%2Fs13058-016-0751-z.pdf
Autor:
Patrycja Gazinska, John H. Hipwell, Sarah E Pinder, David J. Hawkes, Kalnisha Naidoo, Thomy Mertzanidou, Sara Reis
Publikováno v:
Medical Imaging: Digital Pathology
It has been shown that the tumour microenvironment plays a crucial role in regulating tumour progression by a number of different mechanisms, including the remodeling of collagen fibres in tumour-associated stroma. It is still unclear, however, if th