Zobrazeno 1 - 10
of 52
pro vyhledávání: '"John H. H. Williams"'
Publikováno v:
FEBS Open Bio, Vol 13, Iss 10, Pp 1922-1940 (2023)
Endogenous molecules, such as heat shock proteins (HSP), can function as danger signals when released into the extracellular environment in response to cell stress, where they elicit an immune response such as cytokine secretion. There has also been
Externí odkaz:
https://doaj.org/article/969b7896bf3f4d9aac42d911fecbde5a
Autor:
Neil Munro, William Hinton, Michael D. Feher, Mark Joy, Simon de Lusignan, John H. H. Williams
Publikováno v:
Atherosclerosis
Background and aims Statin therapy is administered to patients with high cardiovascular risk. These patients are also at risk for severe course of coronavirus disease 2019 (COVID-19). Statins exhibit not only cardioprotective but also immunomodulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6769e64ecf8e116ab09f749a50d13fd2
http://europepmc.org/articles/PMC8590506
http://europepmc.org/articles/PMC8590506
Autor:
Mark Joy, Simon de Lusignan, Kome Gbinigie, Christopher C Butler, Julian Sherlock, Fd Richard Hobbs, Oliver van Hecke, Manasa Tripathy, John H. H. Williams
Publikováno v:
BJGP Open, Vol 5, Iss 5 (2021)
BJGP Open
BJGP Open
BackgroundThe Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE) has provided in-pandemic evidence that azithromycin and doxycycline were not beneficial in the early primary care management of coronavirus 2019 dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bcc7e091f266b51bec4816b6f07166
https://bjgpopen.org/content/5/5/BJGPO.2021.0087
https://bjgpopen.org/content/5/5/BJGPO.2021.0087
Autor:
Nathan Jeffreys, Anthony A. James, Brian D Nicholson, Clare Bankhead, Spencer A. Thomas, Kam Bhui, Uy Hoang, Harshana Liyanage, Agnieszka Lemanska, Nadia A. S. Smith, John H. H. Williams, Julian Sherlock, Sally Harcourt, Filipa Ferreira, Simon de Lusignan, Gillian E. Smith
Publikováno v:
MIE
The effect of the 2020 pandemic, and of the national measures introduced to control it, is not yet fully understood. The aim of this study was to investigate how different types of primary care data can help quantify the effect of the coronavirus dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe49bd556206b388604aa33775d9a05
https://doi.org/10.3233/shti210277
https://doi.org/10.3233/shti210277
Autor:
Nathan Jeffreys, Xuejuan Fan, Simon de Lusignan, Agnieszka Lemanska, Rebecca Rice, Hajira Dambha-Miller, Harshana Liyanage, John H. H. Williams, Sara Faithfull, Julian Sherlock, Piers A.C. Gatenby, Ali Stunt, Filipa Ferreira
Publikováno v:
MIE
Pancreatic cancer is the 10th most common cancer diagnosed; despite recent advances in many areas of oncology, survival remains poor, in part owing to late diagnosis. Whilst primary care data are used widely for epidemiology and pharmacovigilance, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f9e10d4fa50e0c645a5a49e9b49c12
https://doi.org/10.3233/shti210142
https://doi.org/10.3233/shti210142
Autor:
Christopher C Butler, Julian Sherlock, Oghenekome Gbinigie, O van Hecke, John H. H. Williams, Hobbs Fdr., S de Lusignan, Mark Joy, Manasa Tripathy
BackgroundThe Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE) trial has provided in-pandemic evidence of what does not work in the early primary care management of coronavirus-2019 disease (COVID-19). PRINCIPLE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25efb3e6a35ddff0a72d1dcb2378bc2
https://ora.ox.ac.uk/objects/uuid:5b484b30-82af-4565-9dbd-a338272fa05c
https://ora.ox.ac.uk/objects/uuid:5b484b30-82af-4565-9dbd-a338272fa05c
Autor:
Brian D Nicholson, John H. H. Williams, William Hinton, Jason Oke, Constantinos Koshiaris, Oliver van Hecke, Filipa Ferreira, Nicholas R Jones, Sarah Lay-Flurrie, Clare Bankhead, Joseph J Lee, Harshana Liyanage, Laura C Armitage, Mark Joy, Simon de Lusignan, Michael D. Feher, FD Richard Hobbs, James P Sheppard, Julian Sherlock, Dylan McGagh, Andrew J. Ashworth
Hypertension has been identified as a risk factor for coronavirus disease 2019 (COVID-19) and associated adverse outcomes. This study examined the association between preinfection blood pressure (BP) control and COVID-19 outcomes using data from 460
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ec5cedeb37f57726d77ed4aafe8d59
https://doi.org/10.1161/hypertensionaha.120.16472
https://doi.org/10.1161/hypertensionaha.120.16472
Autor:
John H. H. Williams, Simon de Lusignan
Publikováno v:
BJGP Open, Vol 4, Iss 2 (2020)
BJGP Open
BJGP Open
UK primary care coding of covid-19 is a mess: we need to stop the use of bad codes, and migrate from the use of ugly to good codes, but will only be able to do so when they are finally released . Key data computerised medical record (CMR) systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a7456c038db3a27a05cd762caf336a
https://ora.ox.ac.uk/objects/uuid:ebe47517-89d2-4483-933e-2c368a4fbe0b
https://ora.ox.ac.uk/objects/uuid:ebe47517-89d2-4483-933e-2c368a4fbe0b
Autor:
Mary Sinnathamby, Simon de Lusignan, Gayatri Amirthalingam, Jason Oke, James P Sheppard, Cecilia Okusi, Maria Zambon, Nicholas R Jones, Mark Joy, Fd Richard Hobbs, John H. H. Williams, Jienchi Dorward, Jamie Lopez Bernal, Dylan McGagh, Filipa Ferreira, Julian Sherlock, Joanna Ellis, Brian D Nicholson, Gavin Dabrera, Mary Ramsay, Oluwafunmi Akinyemi, Rachel Byford, Gary Howsam
Publikováno v:
The British Journal of General Practice
BackgroundThe SARS-CoV-2 pandemic has passed its first peak in Europe.AimTo describe the mortality in England and its association with SARS-CoV-2 status and other demographic and risk factors.Design and settingCross-sectional analyses of people with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32111e2fc184824208e349fc5f6137c
http://europepmc.org/articles/PMC7575407
http://europepmc.org/articles/PMC7575407
Autor:
Mark Joy, Maria Zambon, Gary Howsam, Brian D Nicholson, Jamie Lopez-Bernal, Julian Sherlock, Simon de Lusignan, Kevin E. Brown, Dylan McGagh, Cecilia Okusi, Gayatri Amirthalingam, Else Krajenbrink, Ruby S. M. Tsang, John H. H. Williams, FD Richard Hobbs, Rachel Byford, Gavin Dabrera, Filipa Ferreira, Mary Ramsay, Oluwafunmi Akinyemi, Mary Sinnathamby, Jason Oke, Harshana Liyanage, James P Sheppard, Victoria Tzortziou Brown
Publikováno v:
Journal of Infection
© 2020 The Authors Objectives: Few studies report contributors to the excess mortality in England during the first wave of coronavirus disease 2019 (COVID-19) infection. We report the absolute excess risk (AER) of mortality and excess mortality rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053d4c8618cd2bb2e49241656bec36be
https://ora.ox.ac.uk/objects/uuid:c3313475-120d-440c-aa32-8d935d872fed
https://ora.ox.ac.uk/objects/uuid:c3313475-120d-440c-aa32-8d935d872fed