Zobrazeno 1 - 10
of 85
pro vyhledávání: '"John H. Gennari"'
Autor:
Yuda Munarko, Dewan M. Sarwar, Anand Rampadarath, Koray Atalag, John H. Gennari, Maxwell L. Neal, David P. Nickerson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Semantic annotation is a crucial step to assure reusability and reproducibility of biosimulation models in biology and physiology. For this purpose, the COmputational Modeling in BIology NEtwork (COMBINE) community recommends the use of the Resource
Externí odkaz:
https://doaj.org/article/4989d70e88c544a7931c06baa0381d7e
Autor:
Dewan M. Sarwar, Reza Kalbasi, John H. Gennari, Brian E. Carlson, Maxwell L. Neal, Bernard de Bono, Koray Atalag, Peter J. Hunter, David P. Nickerson
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Mathematics and Phy sics-based simulation models have the potential to help interpret and encapsulate biological phenomena in a computable and reproducible form. Similarly, comprehensive descriptions of such models help to ensure
Externí odkaz:
https://doaj.org/article/88988399891345fb876823d486557f18
Autor:
Lucy Lu Wang, G. Thomas Hayman, Jennifer R. Smith, Monika Tutaj, Mary E. Shimoyama, John H. Gennari
Publikováno v:
Journal of Biomedical Semantics, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background To improve the outcomes of biological pathway analysis, a better way of integrating pathway data is needed. Ontologies can be used to organize data from disparate sources, and we leverage the Pathway Ontology as a unifying ontolog
Externí odkaz:
https://doaj.org/article/a48580a1c17f422ba60351f47a585c74
Autor:
John H. Gennari, Woosub Shin, Maxwell Lewis Neal, Joseph L. Hellerstein, David P. Nickerson, Yuda Munarko, Anand Rampadarath, Herbert M. Sauro
The interests in repurposing and reusing systems biology models have been growing in recent years. Semantic annotations play an important role for this, as they provide crucial information on the meanings and functions of models. However, there are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::856f0e75ee5c058a4543f2b7442d9f0a
https://doi.org/10.1101/2021.10.09.463757
https://doi.org/10.1101/2021.10.09.463757
Autor:
Maxwell Lewis Neal, David P. Nickerson, Goksel Misirli, Dagmar Waltemath, Matthias König, John H. Gennari
Publikováno v:
Journal of Integrative Bioinformatics, Vol 18, Iss 3 (2021)
Journal of Integrative Bioinformatics
Journal of Integrative Bioinformatics
A standardized approach to annotating computational biomedical models and their associated files can facilitate model reuse and reproducibility among research groups, enhance search and retrieval of models and data, and enable semantic comparisons be
Autor:
David P. Nickerson, Maxwell Lewis Neal, John H. Gennari, Ciaran Welsh, Herbert M. Sauro, Anand Rampadarath
Publikováno v:
Bioinformatics
Summary As the number and complexity of biosimulation models grows, so do demands for tools that can help users better understand models and make those models more findable, shareable and reproducible. Consistent model annotation is a step toward the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c0ebe42f16969de8edd4d92ddcbda7
https://europepmc.org/articles/PMC8665746/
https://europepmc.org/articles/PMC8665746/
This book introduces semantic representations of multiscale, multidomain physiological systems that link to qualitative reasoning and to quantitative analysis of biophysical processes in health and disease. Two major public health problems, diabetes
Autor:
Herbert M. Sauro, Michael L. Blinov, John H. Gennari, David P. Nickerson, Ion I. Moraru, Jonathan R. Karr
Although reproducibility is a core tenet of the scientific method, it remains challenging to reproduce many results. Surprisingly, this also holds true for computational results in domains such as systems biology where there have been extensive stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02ecfc7dbd64ff3f72e796215d00b61
Publikováno v:
Journal of Integrative Bioinformatics
Journal of Integrative Bioinformatics, Vol 17, Iss 2-3 (2020)
Journal of Integrative Bioinformatics, Vol 17, Iss 2-3 (2020)
A standardized approach to annotating computational biomedical models and their associated files can facilitate model reuse and reproducibility among research groups, enhance search and retrieval of models and data, and enable semantic comparisons be
Deep phenotyping of cardiac function in heart transplant patients using cardiovascular system models
Autor:
N. Payton Woodall, Mette S. Olufsen, Brian E. Carlson, Karam G. Kim, Amanda L. Colunga, Todd F. Dardas, John H. Gennari
Publikováno v:
The Journal of physiologyReferences. 598(15)
Heart transplant patients are followed with periodic right heart catheterizations (RHCs) to identify post-transplant complications and guide treatment. Post-transplant positive outcomes are associated with a steady reduction of right ventricular and