Zobrazeno 1 - 10
of 113
pro vyhledávání: '"John H. Eldridge"'
Autor:
Demetrius Matassov, Lisa Evans DeWald, Stefan Hamm, Rebecca M. Nowak, Cheryl S. Gerardi, Theresa E. Latham, Rong Xu, Amara Luckay, Tracy Chen, Marc Tremblay, Jeffry Shearer, Melissa Wynn, John H. Eldridge, Kelly Warfield, Kevin Spurgers
Publikováno v:
Vaccines, Vol 12, Iss 8, p 858 (2024)
There are currently no prophylactic vaccines licensed to protect against Lassa fever caused by Lassa virus (LASV) infection. The Emergent BioSolutions (EBS) vaccine candidate, EBS-LASV, is being developed for the prevention of Lassa fever. EBS-LASV i
Externí odkaz:
https://doaj.org/article/5ac6e9310ddd44a58999bee90fd7b27a
Autor:
Lukkana Suksanpaisan, Rong Xu, Mulu Z. Tesfay, Carolyn Bomidi, Stefan Hamm, Rianna Vandergaast, Nathan Jenks, Michael B. Steele, Ayuko Ota-Setlik, Hinna Akhtar, Amara Luckay, Rebecca Nowak, Kah Whye Peng, John H. Eldridge, David K. Clarke, Stephen J. Russell, Rosa Maria Diaz
Publikováno v:
Molecular Therapy: Oncolytics, Vol 10, Iss , Pp 1-13 (2018)
Immunotherapy for HPVPOS malignancies is attractive because well-defined, viral, non-self tumor antigens exist as targets. Several approaches to vaccinate therapeutically against HPV E6 and E7 antigens have been adopted, including viral platforms suc
Externí odkaz:
https://doaj.org/article/3396dace4a2548be8e2c17cb86f01e32
Autor:
Courtney Woolsey, Viktoriya Borisevich, Krystle N Agans, Rachel O’Toole, Karla A Fenton, Mack B Harrison, Abhishek N Prasad, Daniel J Deer, Cheryl Gerardi, Nneka Morrison, Robert W Cross, John H Eldridge, Demetrius Matassov, Thomas W Geisbert
Publikováno v:
The Journal of Infectious Diseases.
Background The family Filoviridae consists of several virus members known to cause significant mortality and disease in humans. Among these, Ebola virus (EBOV), Marburg virus (MARV), Sudan virus (SUDV), and Bundibugyo virus (BDBV) are considered the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bea161e8dedaa898d114c294fbfd820
https://doi.org/10.1093/infdis/jiad157
https://doi.org/10.1093/infdis/jiad157
Autor:
Courtney Woolsey, Robert W. Cross, Krystle N. Agans, Viktoriya Borisevich, Daniel J. Deer, Joan B. Geisbert, Cheryl Gerardi, Theresa E. Latham, Karla A. Fenton, Michael A. Egan, John H. Eldridge, Thomas W. Geisbert, Demetrius Matassov
BackgroundMarburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent emergence in West Africa for the first time. Although a recombinant vesicular st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ed43944e24748786760c0fd6b34653
https://doi.org/10.1101/2022.01.22.477345
https://doi.org/10.1101/2022.01.22.477345
Autor:
Robert W. Cross, Rong Xu, Susan E. Witko, Ayuko Ota-Setlik, Lena Soukieh, Thomas W. Geisbert, Amara Luckay, Karla A. Fenton, Daniel J. Deer, Krystle N. Agans, John H. Eldridge, Theresa E. Latham, Chad E. Mire, Demetrius Matassov, Heinz Feldmann, Rebecca M. Nowak, Joan B. Geisbert, Christian T. Happi, Cheryl S. Gerardi, Stefan Hamm
Publikováno v:
Journal of Clinical Investigation. 130:539-551
Recent occurrences of filoviruses and the arenavirus Lassa virus (LASV) in overlapping endemic areas of Africa highlight the need for a prophylactic vaccine that would confer protection against all of these viruses that cause lethal hemorrhagic fever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff5e32f0f3faea9c6d40d076939d119
https://doi.org/10.1172/jci131958
https://doi.org/10.1172/jci131958
Autor:
Marc Gurwith, Antony S. Dimitrov, Susan Sciotto-Brown, Stefan Hamm, Robert T. Chen, Emily R. Smith, Rong Xu, Luz Hermida, Tracy Chen, Marc Tremblay, Michael A. Egan, John H. Eldridge, Demetrius Matassov
Publikováno v:
Vaccine. 39(38)
Auro Vaccines LLC has developed a protein vaccine to prevent disease from Nipah and Hendra virus infection that employs a recombinant soluble Hendra glycoprotein (HeV-sG) adjuvanted with aluminum phosphate. This vaccine is currently under clinical ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ecdc6cfe2be6345c231309d54bd8de
https://pubmed.ncbi.nlm.nih.gov/34373117
https://pubmed.ncbi.nlm.nih.gov/34373117
Autor:
Karla A. Fenton, Ilhem Messaoudi, Robert W. Cross, Daniel J. Deer, Courtney Woolsey, Cheryl S. Gerardi, Joan B. Geisbert, Viktoriya Borisevich, Thomas W. Geisbert, John H. Eldridge, Demetrius Matassov, Krystle N. Agans, Allen Jankeel, Theresa E. Latham, Chad E. Mire
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Postexposure immunization can prevent disease and reduce transmission following pathogen exposure. The rapid immunostimulatory properties of recombinant vesicular stomatitis virus (rVSV)-based vaccines make them suitable postexposure treatments again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f918431681c3f684b30842324b11ca9
https://pubmed.ncbi.nlm.nih.gov/32080323
https://pubmed.ncbi.nlm.nih.gov/32080323
Autor:
David K. Clarke, Theresa E. Latham, Michael A. Egan, Amara Luckay, Lucy A. Ward, Ayuko Ota-Setlik, Terry J. Higgins, Tracy Chen, Rong Xu, Janice M. Rusnak, Marc Tremblay, Susan E. Witko, Demetrius Matassov, Susan Sciotto-Brown, Luz Hermida, Cheryl S. Gerardi, John H. Eldridge
Publikováno v:
The Lancet. Infectious diseases. 20(4)
Summary Background The safety and immunogenicity of a highly attenuated recombinant vesicular stomatitis virus (rVSV) expressing HIV-1 gag (rVSVN4CT1-HIV-1gag1) was shown in previous phase 1 clinical studies. An rVSV vector expressing Ebola virus gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81da33fefbeb1d50c33bf76755e0d37
https://pubmed.ncbi.nlm.nih.gov/31952924
https://pubmed.ncbi.nlm.nih.gov/31952924
Autor:
Thomas W. Geisbert, Krystle N. Agans, Chad E. Mire, Viktoriya Borisevich, Courtney Woolsey, Robert W. Cross, Demetrius Matassov, John H. Eldridge, Karla A. Fenton, Daniel J. Deer, Joan B. Geisbert
Publikováno v:
The Journal of Infectious Diseases
A recombinant vesicular stomatitis virus (rVSV) expressing the Marburg virus (MARV) Musoke variant glycoprotein fully protects macaques against 2 MARV variants and Ravn virus as a preventive vaccine and MARV variant Musoke as a postexposure treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e0facffecf6319f13de1df8c07e284
https://pubmed.ncbi.nlm.nih.gov/29939296
https://pubmed.ncbi.nlm.nih.gov/29939296
Autor:
Rong Xu, Karla A. Fenton, Ayuko Ota-Setlik, Krystle N. Agans, John H. Eldridge, Chad E. Mire, Demetrius Matassov, Theresa E. Latham, David K. Clarke, Michael A. Egan, Thomas W. Geisbert, Joan B. Geisbert
Publikováno v:
Nature
The family Filoviridae contains three genera, Ebolavirus (EBOV), Marburg virus, and Cuevavirus1. Some members of the EBOV genus, including Zaire ebolavirus (ZEBOV), can cause lethal hemorrhagic fever in humans. During 2014 an unprecedented ZEBOV outb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f128ddf9358c895ead849ad2cfd2fb0
https://doi.org/10.1038/nature14428
https://doi.org/10.1038/nature14428