Zobrazeno 1 - 10
of 11
pro vyhledávání: '"John H. Brekke"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162853 (2016)
The development and utilization of three-dimensional cell culture platforms has been gaining more traction. Three-dimensional culture platforms are capable of mimicking in vivo microenvironments, which provide greater physiological relevance in compa
Externí odkaz:
https://doaj.org/article/8d128d53ce8a457691fde0d74a1d52a2
Autor:
Timothy O'Brien, Weili Chen, Kerri T. Haider, Qi Wang, Efrosini Kokkoli, Amanda L. Vegoe, James R. Dutton, Beth A. Lindborg, Paul J. Orchard, Francisco Pelaez, John H. Brekke, Cindy R. Eide, Jakub Tolar, Scott L. Venhuizen, Connor B. Ulrich, Sandhya Subramaniam, Carolyn M. Scott, Susan A. Keirstead
Publikováno v:
Stem Cells Translational Medicine. 5:970-979
Tissue organoids are a promising technology that may accelerate development of the societal and NIH mandate for precision medicine. Here we describe a robust and simple method for generating cerebral organoids (cOrgs) from human pluripotent stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfeda95660d8b5dea9d18c59f770f386
https://doi.org/10.5966/sctm.2015-0305
https://doi.org/10.5966/sctm.2015-0305
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162853 (2016)
PLoS ONE
PLoS ONE
The development and utilization of three-dimensional cell culture platforms has been gaining more traction. Three-dimensional culture platforms are capable of mimicking in vivo microenvironments, which provide greater physiological relevance in compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec432ee1c567fef809ed24f34ffde27f
http://europepmc.org/articles/PMC5025053?pdf=render
http://europepmc.org/articles/PMC5025053?pdf=render
Autor:
Carolyn M. Scott, Connor B. Ulrich, John H. Brekke, Efrosini Kokkoli, Timothy O'Brien, Lee Sandquist, Beth A. Lindborg, Yi Wen Chai
Publikováno v:
Tissue engineering. Part A. 21(11-12)
Three-dimensional (3D) cell culture platforms are increasingly utilized due to their ability to more closely mimic the in vivo microenvironment compared to traditional two-dimensional methods. Limitations of currently available 3D materials include l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccea352eeaf9e28df98133dab714af5
https://pubmed.ncbi.nlm.nih.gov/25748146
https://pubmed.ncbi.nlm.nih.gov/25748146
Autor:
John H. Brekke
Publikováno v:
Tissue engineering. 2(2)
Highly pure, recombinant human osteoinductive proteins make it possible to consider programmable osteoneogenesis. Until recently, it was believed that a bioresorbable excipient or physiologic solution would suffice to transport osteoinductive agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bdb748264201534e41854cd721169e
https://pubmed.ncbi.nlm.nih.gov/19877933
https://pubmed.ncbi.nlm.nih.gov/19877933
Autor:
John H. Brekke, John W. Moore
Publikováno v:
Journal of Oral and Maxillofacial Surgery. 48:808-812
Presented are 18 cases of foreign body giant cell reaction in mandibular third molar extraction wounds previously treated with 40 mg of dry tetracycline powder carried into the wound with a biodegradable polymer dressing. The lesions vary in intensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b38360a7d3d7d088a6715c259a2aa6
https://doi.org/10.1016/0278-2391(90)90338-3
https://doi.org/10.1016/0278-2391(90)90338-3
Autor:
V. J. Jameson, Evan B. Douple, John H. Brekke, Julius M. Liptak, William S. Dernell, Stephen J. Withrow, Rodney C. Straw, Jeffery L. Johnson, Barbara E. Powers
Publikováno v:
Annals of surgical oncology. 11(7)
The rate of local recurrence of osteosarcoma after limb-sparing surgery in dogs and humans has been reported up to 28%. The primary purpose of this study was to determine whether a biodegradable cisplatin-containing implant (OPLA-Pt), inserted into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a97b8d0e838884febe637568793ec7
https://pubmed.ncbi.nlm.nih.gov/15231525
https://pubmed.ncbi.nlm.nih.gov/15231525
Publikováno v:
Tissue engineering. 6(4)
This paper provides practical illustrations in the use of osteoinductive devices (biomaterial carriers coupled with osteoinductive morphogens) for bone tissue engineering. We discuss the considerations relative to the implantation of these devices th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d1a383bbb0e578d83de55533408642
https://pubmed.ncbi.nlm.nih.gov/10992440
https://pubmed.ncbi.nlm.nih.gov/10992440
Autor:
Evan B. Douple, John H. Brekke, Mary J. Lafferty, William S. Dernell, Stephen J. Withrow, Susan E. Lana, Susan M. LaRue
Publikováno v:
Veterinary radiologyultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 38(6)
Thirteen dogs with malignant tumors of the nasal cavity were treated with a combination of slow release cisplatin and megavoltage radiation. Radiation was delivered on a Monday through Friday schedule using a 6 MV linear accelerator. The median total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584fcf7fa7dfa4b893f4aa3f9d8d75db
https://pubmed.ncbi.nlm.nih.gov/9402717
https://pubmed.ncbi.nlm.nih.gov/9402717
Autor:
Evan B. Douple, Rodney C. Straw, Mary F. Cooper, Barbara E. Powers, John H. Brekke, Deborah S. Greco, Stephen J. Withrow, P. D. Schwarz
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 12(6)
This study was performed to determine the pharmacokinetics and local and systemic effects of cis-diamminedichloroplatinum II (cisplatin) released from an open-cell polylactic acid polymer when the drug delivery device was placed adjacent to a cortica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1980c4b340aeba4afa93a7ef0ce2e610
https://pubmed.ncbi.nlm.nih.gov/7983562
https://pubmed.ncbi.nlm.nih.gov/7983562