Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John H Loughran"'
Autor:
Sujith Dassanayaka, Samir V. Patel, Sadip Pant, Carlo R. Bartoli, Wasiq Rawasia, Allen Cheng, John H Loughran, Buddhadeb Dawn, Tyler Kilgore, Michael P. Flaherty
Publikováno v:
Circulation Research. 120:692-700
Rationale: Acute kidney injury (AKI) is common during high-risk percutaneous coronary intervention (PCI), particularly in those with severely reduced left ventricular ejection fraction. The impact of partial hemodynamic support with a microaxial perc
Publikováno v:
Lancet (London, England). 379(9819)
The paper by Roberto Bolli and colleagues (Nov 26, p 1847) on cardiac progenitor cell treatment for ischaemic heart failure is a milestone in the history of cardiac cell therapy. However, we noticed some points that possibly interfere with interpreta
Autor:
Jay H. Traverse, Robert D. Simari, James T. Willerson, Ray F. Ebert, Atul R. Chugh, Joshua M. Hare, Rachel W. Vojvodic, Lem Moyé, Timothy D. Henry, Phillip C. Yang, Ivonne Hernandez-Schulman, Aisha Khan, Shelly L. Sayre, Roberto Bolli, Emerson C. Perin, Darcy L. DiFede, Doris A. Taylor, Keith L. March, Michelle Cohen, Raul D. Mitrani, John H Loughran, Judy Bettencourt, Carl J. Pepine, Joao A.C. Lima
Rationale: Autologous bone marrow mesenchymal stem cells (MSCs) and c-kit + cardiac progenitor cells (CPCs) are 2 promising cell types being evaluated for patients with heart failure (HF) secondary to ischemic cardiomyopathy. No information is availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef31ee148b665571b56f121553caecd
https://europepmc.org/articles/PMC5993622/
https://europepmc.org/articles/PMC5993622/
Autor:
Emerson C. Perin, Carl J. Pepine, Dejian Lai, Sara Richman, Lemuel A. Moyé, Dana D Leach, Ray F. Ebert, Shari Williams, Eileen M. Handberg, Shelly L. Sayre, Michael P. Murphy, Joshua M. Hare, Bharath Ambale-Venkatesh, Amir Gahremanpour, R. David Anderson, Joanne Goldman, Jeanette Bloom, Lara M. Simpson, Benjamin Cheong, James T. Willerson, Elsie Gyang Ross, Darcy L. DiFede, Emily Caldwell, Jay H. Traverse, Roberto Bolli, Ivonne Hernandez Schulman, Micheline Resende, Timothy D. Henry, Omaida Velasquez, Alan T. Hirsch, Raja Muthupillai, Joao A.C. Lima, Fouzia Khan, Michelle R. Santoso, Nicholas J. Leeper, Keith L. March, Phillip C. Yang, Michelle Cohen, Ronald L. Dalman, Patricia G'Sell, Jason Q Alexander, Doris A. Taylor, Vijaykumar S. Kasi, Linda B. Piller, Judy Bettencourt, Ganesh Raveendran, April G. Durett, John H Loughran, Adrian P. Gee, Nichole Piece, Scott A. Berceli, Robert D. Simari, Barb Bruhn-Ding, Rachel W. Vojvodic, William R. Hiatt
Background: Atherosclerotic peripheral artery disease affects 8% to 12% of Americans >65 years of age and is associated with a major decline in functional status, increased myocardial infarction and stroke rates, and increased risk of ischemic amputa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75018469b455d27883ed4cd4c2e7085d
https://europepmc.org/articles/PMC5388585/
https://europepmc.org/articles/PMC5388585/
Publikováno v:
Nature Reviews Cardiology. 10:519-530
Heart failure is a devastating condition, the progression of which culminates in a mismatch of oxygen supply and demand, with limited options for treatment. Heart failure has several underlying causes including, but not limited to, ischaemic heart di
Autor:
Brad Sutton, Andrew P. DeFilippis, Lorrel E. Brown, Tauqir Puthawala, Peter J. Pronovost, John H Loughran
Publikováno v:
Journal of intensive care medicine. 32(2)
Prior to the advent of the coronary care unit (CCU), patients having an acute myocardial infarction (AMI) were managed on the general medicine wards with reported mortality rates of greater than 30%. The first CCUs are believed to be responsible for
Autor:
Sadip Pant, Michael P. Flaherty, Sujith Dassanayaka, Tyler Kilgore, Buddhadeb Dawn, Wasiq Faraz Rawasia, Carlo R. Bartoli, Allen Cheng, John H Loughran
Publikováno v:
Journal of the American College of Cardiology. 68:B49-B50
Acute kidney injury (AKI) is common during high-risk percutaneous coronary intervention (PCI) with high-risk clinical and anatomic features, particularly in patients with low ejection fractions (EF). This retrospective, single-center study tested the
Publikováno v:
Current heart failure reports. 10(1)
Cardiac repair through the use of regenerative medicine has been a considerable research focus over the last decade. Several stem cell types have been investigated over this timeframe as potential candidates to target post-infarction heart failure. T
Autor:
Roberto Bolli, John H Loughran, Patroklos Pappas, Jan Kajstura, Marcus F. Stoddard, Julius B Elmore, Garth M. Beache, Antone Tatooles, Atul R. Chugh, Nathan Mewton, Mark S. Slaughter, Joao A.C. Lima, Piero Anversa
Background— SCIPIO is a first-in-human, phase 1, randomized, open-label trial of autologous c-kit + cardiac stem cells (CSCs) in patients with heart failure of ischemic etiology undergoing coronary artery bypass grafting (CABG). In the present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ac7410491ebabcccb260ff8f635c5b
https://europepmc.org/articles/PMC3448934/
https://europepmc.org/articles/PMC3448934/
Publikováno v:
Current atherosclerosis reports. 14(5)
The increasing prevalence of heart failure, in the US and worldwide, poses a significant burden to patients, practitioners, and healthcare systems. Hence, there is a pressing need for alternative therapies to enhance the current treatment armamentari