Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John H, Proffitt"'
Autor:
Steve A. Seelig, John H. Proffitt, Kris Jacobson, Kimberly A. Wilber, Beth Blondin, Susan C. Van Stedum, John S. Coon, Larry E. Morrison, Benita T. Henderson, Mona S. Legator, Anna O'Hare
Publikováno v:
Genes, chromosomescancer. 40(1)
ERBB2 is one of the most important oncogenes in breast cancer, and its disordered expression is commonly associated with gene amplification. Amplification of at least one gene near ERBB2, topoisomerase IIalpha (TOP2A), has been shown to be clinically
Autor:
Jennifer Harbison, Lisa Smith, Nyla A. Heerema, John H. Proffitt, Ian W. Flinn, Marcy L. Hackbarth, Thomas S. Lin, John C. Byrd, Mollie E. Moran, Michael R. Grever, Gerard Lozanski, Margaret Lucas, David M. Lucas, Jennifer Webb
Publikováno v:
Blood. 103(9)
The presence of p53 mutation or deletion predicts for poor response to conventional therapy in chronic lymphocytic leukemia (CLL). We sought to determine whether the humanized anti-CD52 antibody alemtuzumab was effective in this patient group. Thirty
Autor:
John C, Byrd, Lisa, Smith, Marcy L, Hackbarth, Ian W, Flinn, Donn, Young, John H, Proffitt, Nyla A, Heerema
Publikováno v:
Cancer research. 63(1)
Select cytogenetic abnormalities such as del(17)(p13.1) and del(11)(q22-q23)predict rapid disease progression and inferior survival in chronic lymphocytic leukemia (CLL). We sought to determine the impact of the four most common interphase cytogeneti
Autor:
Catherine Godon, Régis Bataille, Nicole Dastugue, M J Mozziconacci, Pascaline Talmant, Marina Lafage-Pochitaloff, John H. Proffitt, Hervé Avet-Loiseau, Hackbarth M
Publikováno v:
Leukemia. 16(9)
Recurrent chromosomal rearrangements are observed in many leukemia subtypes. Recently, it has been shown that several of these translocations/inversions were associated with the loss of sequences located in the vicinity of the chromosomal breakpoints
Autor:
John H. Proffitt, Nelly Robillard, S. Minvielle, Hervé Avet-Loiseau, H Beris, J-L Harousseau, Florence Magrangeas, Soraya Wuilleme, Laurence Lodé
Publikováno v:
Blood. 104:4857-4857
Ploidy appears as an important parameter in both the biology and the clinical evolution of multiple myeloma. However, its evaluation requires either a successful karyotyping (obtained in 30% of the patients), or a DNA index calculation by flow cytome
Autor:
Kris K. Jacobson, Larry E. Morrison, Benita T. Henderson, Beth A. Blondin, Kimberly A. Wilber, Mona S. Legator, Anna O'Hare, Susan C. Van Stedum, John H. Proffitt, Steve A. Seelig, John S. Coon
Publikováno v:
Genes, Chromosomes & Cancer; May2004, Vol. 40 Issue 1, p19-31, 13p
Publikováno v:
Experimental Biology and Medicine. 155:55-58
Data from studies with liver homogenates indicate livers of different species differ in their ability to synthesize taurine from various substrates. Rat liver synthesizes taurine rapidly from cystine sulfinic acid (CSA) (1, 2), whereas cat and human
Autor:
John H. Proffitt
Publikováno v:
Molecular and cellular biology. 5(6)
Five DNase I-hypersensitive regions were associated with the Saccharomyces cerevisiae galactose gene cluster during both galactose induction and glucose repression of transcription. Four hypersensitive regions were located in areas flanking the GAL c