Zobrazeno 1 - 10
of 250
pro vyhledávání: '"John H, Powers"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract U.S. laws enacted since 1983 have aimed to enhance the development and marketing of new pharmaceutical products. We thoroughly characterized all new molecular entities, therapeutic biologics, and gene and cell therapies approved by the US Fo
Externí odkaz:
https://doaj.org/article/497c8a8024ce4a58a6dc9ca05805db86
Autor:
Sacha Satram, Parima Ghafoori, Carolina M. Reyes, Tom J. H. Keeley, Helen J. Birch, Dimitra Brintziki, Melissa Aldinger, Elizabeth Alexander, Amanda Lopuski, Elias H. Sarkis, Anil Gupta, Adrienne E. Shapiro, John H. Powers
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Background The COMET-ICE trial demonstrated that sotrovimab clinically and statistically significantly reduces the risk of all-cause > 24-h hospitalization or death due to any cause among patients with COVID-19 at high risk of disease progre
Externí odkaz:
https://doaj.org/article/6f5b2215640644699e5c1eb8151e8b5b
Autor:
Emilie Goguet, Cara H. Olsen, William A. Meyer, Sara Ansari, John H. Powers, Tonia L. Conner, Si’Ana A. Coggins, Wei Wang, Richard Wang, Luca Illinik, Margaret Sanchez Edwards, Belinda M. Jackson-Thompson, Monique Hollis-Perry, Gregory Wang, Yolanda Alcorta, Mimi A. Wong, David Saunders, Roshila Mohammed, Bolatito Balogun, Priscilla Kobi, Lakeesha Kosh, Kimberly Bishop-Lilly, Regina Z. Cer, Catherine E. Arnold, Logan J. Voegtly, Maren Fitzpatrick, Andrea E. Luquette, Francisco Malagon, Orlando Ortega, Edward Parmelee, Julian Davies, Alyssa R. Lindrose, Hannah Haines-Hull, Matthew S. Moser, Emily C. Samuels, Marana S. Rekedal, Elizabeth K. Graydon, Allison M. W. Malloy, David R. Tribble, Timothy H. Burgess, Wesley Campbell, Sara Robinson, Christopher C. Broder, Robert J. O’Connell, Carol D. Weiss, Simon Pollett, Eric D. Laing, Edward Mitre
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe sought to determine pre-infection correlates of protection against SARS-CoV-2 post-vaccine inzfections (PVI) acquired during the first Omicron wave in the United States.MethodsSerum and saliva samples from 176 vaccinated adults were co
Externí odkaz:
https://doaj.org/article/3a4aa329b61b4813a7a5631dfb280ce2
Autor:
Ana Estela Gamiño-Arroyo, José Arellano-Galindo, Paola Del Carmen Guerra-de-Blas, Ana M. Ortega-Villa, Allyson Mateja, Beatriz Llamosas-Gallardo, Ana A. Ortíz-Hernández, Rafael Valdéz-Vázquez, Alejandra Ramírez-Venegas, Arturo Galindo-Fraga, Ma Lourdes Guerrero, Pilar Ramos-Cervantes, Luis Mendoza-Garcés, Mónica González-Matus, Carmen Marroquín-Rojas, Juan Xicohtencatl-Cortes, Sara A. Ochoa, Ariadna Cruz-Córdova, John H. Powers, Guillermo Miguel Ruiz-Palacios, John Beigel, Sarbelio Moreno-Espinosa
Publikováno v:
The Lancet Regional Health. Americas, Vol 29, Iss , Pp 100647- (2024)
Summary: Background: Human Bocaviruses (HBoV) can cause acute respiratory tract infections. High coinfection rates cloud its pathogenicity. This study sought to describe the clinical features of HBoV1 disease in children and adults with Influenza-lik
Externí odkaz:
https://doaj.org/article/404ddf3005a9433e9faf0b47b00d1e74
Publikováno v:
Frontiers in Antibiotics, Vol 2 (2023)
Antimicrobial resistance (AMR) is a challenge because it is associated with worse patient outcomes. To solve the problem will take development of interventions and policies which improve patient outcomes by prolonging survival, improving patient symp
Externí odkaz:
https://doaj.org/article/0c3ede94ad574a8a9cb26f5865b10927
Autor:
Oriana Ciani, Anthony M. Manyara, Philippa Davies, Derek Stewart, Christopher J. Weir, Amber E. Young, Jane Blazeby, Nancy J. Butcher, Sylwia Bujkiewicz, An-Wen Chan, Dalia Dawoud, Martin Offringa, Mario Ouwens, Asbjørn Hróbjartssson, Alain Amstutz, Luca Bertolaccini, Vito Domenico Bruno, Declan Devane, Christina D.C.M. Faria, Peter B. Gilbert, Ray Harris, Marissa Lassere, Lucio Marinelli, Sarah Markham, John H. Powers, Yousef Rezaei, Laura Richert, Falk Schwendicke, Larisa G. Tereshchenko, Achilles Thoma, Alparslan Turan, Andrew Worrall, Robin Christensen, Gary S. Collins, Joseph S. Ross, Rod S. Taylor
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102283- (2023)
Summary: Background: Interventional trials that evaluate treatment effects using surrogate endpoints have become increasingly common. This paper describes four linked empirical studies and the development of a framework for defining, interpreting and
Externí odkaz:
https://doaj.org/article/8e9e1a2069b3446189f61f2a4f887092
Autor:
Nusrat J Epsi, John H Powers, David A Lindholm, Katrin Mende, Allison Malloy, Anuradha Ganesan, Nikhil Huprikar, Tahaniyat Lalani, Alfred Smith, Rupal M Mody, Milissa U Jones, Samantha E Bazan, Rhonda E Colombo, Christopher J Colombo, Evan C Ewers, Derek T Larson, Catherine M Berjohn, Carlos J Maldonado, Paul W Blair, Josh Chenoweth, David L Saunders, Jeffrey Livezey, Ryan C Maves, Margaret Sanchez Edwards, Julia S Rozman, Mark P Simons, David R Tribble, Brian K Agan, Timothy H Burgess, Simon D Pollett, EPICC COVID-19 Cohort Study Group
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281272 (2023)
BackgroundAccurate COVID-19 prognosis is a critical aspect of acute and long-term clinical management. We identified discrete clusters of early stage-symptoms which may delineate groups with distinct disease severity phenotypes, including risk of dev
Externí odkaz:
https://doaj.org/article/d9810718361f4985b05aa9cc21c2678a
Publikováno v:
BMJ Medicine, Vol 1, Iss 1 (2022)
Objective To review the clinical evidence, regulatory background, and cost of antibiotics approved by the US Food and Drug Administration (FDA), 2016-19.Design Cohort study of FDA approved drugs.Data sources FDA databases, ClinicalTrials.gov, and dru
Externí odkaz:
https://doaj.org/article/a7181d4365d84785940a8e01489311f2
Autor:
Pablo F. Belaunzarán-Zamudio, Héctor Armando Rincón León, Sandra Caballero Sosa, Emilia Ruiz, José Gabriel Nájera Cancino, Paul Rodriguez de La Rosa, María de Lourdes Guerrero Almeida, John H. Powers, John H. Beigel, Sally Hunsberger, Karina Trujillo, Pilar Ramos, Fernando J. Arteaga-Cabello, Alexander López-Roblero, Raydel Valdés-Salgado, Hugo Arroyo-Figueroa, Eli Becerril, Guillermo Ruiz-Palacios, for the Mexican Emerging Infectious Diseases Clinical Research Network (La Red)
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background The introduction of Zika and chikungunya to dengue hyperendemic regions increased interest in better understanding characteristics of these infections. We conducted a cohort study in Mexico to evaluate the natural history of Zika
Externí odkaz:
https://doaj.org/article/e2b4f4ee29e341e18a928a4f4e79247b
Autor:
Belinda M. Jackson-Thompson, Emilie Goguet, Eric D. Laing, Cara H. Olsen, Simon Pollett, K. Monique Hollis-Perry, Santina E. Maiolatesi, Luca Illinik, Kathleen F. Ramsey, Anatalio E. Reyes, Yolanda Alcorta, Mimi A. Wong, Julian Davies, Orlando Ortega, Edward Parmelee, Alyssa R. Lindrose, Matthew Moser, Elizabeth Graydon, Andrew G. Letizia, Christopher A. Duplessis, Anuradha Ganesan, Kathleen P. Pratt, Allison M. Malloy, David W. Scott, Stephen K. Anderson, Andrew L. Snow, Clifton L. Dalgard, John H. Powers, David Tribble, Timothy H. Burgess, Christopher C. Broder, Edward Mitre
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background SARS-CoV-2 is a recently emerged pandemic coronavirus (CoV) capable of causing severe respiratory illness. However, a significant number of infected people present as asymptomatic or pauci-symptomatic. In this prospective assessme
Externí odkaz:
https://doaj.org/article/92bd135e155348ab950f477df74eb6d7