Zobrazeno 1 - 10
of 215
pro vyhledávání: '"John H, Lee"'
Autor:
Jacob Vine, John H. Lee, Lakshman Balaji, Anne V. Grossestreuer, Andrea Morton, Natia Peradze, Nivedha Antony, Noa Berlin, Max S. Kravitz, Shannon B. Leland, Katherine Berg, Ari Moskowitz, Michael W. Donnino, Xiaowen Liu
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-8 (2024)
Abstract Background Diabetic ketoacidosis (DKA) is a potentially life-threatening disorder associated with severe alterations in metabolism and acid–base status. Mitochondrial dysfunction is associated with diabetes and its complications. Thiamine
Externí odkaz:
https://doaj.org/article/9b14c3e46a3740048246ed3f7e11b098
Autor:
John H. Lee, Larry A. Nathanson, Ryan C. Burke, Brian W. Anthony, Nathan I. Shapiro, Alon S. Dagan
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives This study aimed to compare the different respiratory rate (RR) monitoring methods used in the emergency department (ED): manual documentation, telemetry, and capnography. Methods This is a retrospective study using recorded patie
Externí odkaz:
https://doaj.org/article/3ec4848531e44c678647a22802e3689d
Autor:
Cole Citrenbaum, Juliana Corlier, Doan Ngo, Nikita Vince-Cruz, Andrew Wilson, Scott A. Wilke, David Krantz, Reza Tadayonnejad, Nathaniel Ginder, Jennifer Levitt, John H. Lee, Michael K. Leuchter, Thomas B. Strouse, Andrew Corse, Pooja Vyas, Andrew F. Leuchter
Publikováno v:
Brain Stimulation, Vol 16, Iss 6, Pp 1566-1571 (2023)
Background: Repetitive Transcranial Magnetic Stimulation (rTMS) is an effective treatment for Major Depressive Disorder (MDD). Two common rTMS protocols, 10 Hz and intermittent theta burst stimulation (iTBS), have comparable rates of efficacy in grou
Externí odkaz:
https://doaj.org/article/b8acf9de2f174c8594254cfe07c02bab
Autor:
Manbir Sandhu, Aaron Cho, Ning Ma, Elizaveta Mukhaleva, Yoon Namkung, Sangbae Lee, Soumadwip Ghosh, John H. Lee, David E. Gloriam, Stéphane A. Laporte, M. Madan Babu, Nagarajan Vaidehi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
G protein coupled receptors (GPCRs) can couple to different Gα protein subfamilies either selectively or promiscuously. Here, the authors use computational approach to show that selectivity determinants are at the periphery of the GPCR—G protein i
Externí odkaz:
https://doaj.org/article/3f58c0dca0e94af083460b63eb5f6506
Autor:
Tran X. N. Huy, Trang T. Nguyen, Alisha W. B. Reyes, Heejin Kim, WonGi Min, Hu J. Lee, John H. Lee, Suk Kim
Publikováno v:
Pathogens, Vol 11, Iss 5, p 596 (2022)
The effects of Cobalt (II) chloride (CoCl2) in the context of Brucella abortus (B. abortus) infection have not been evaluated so far. Firstly, we found that CoCl2 treatment inhibited the phagocytosis of B. abortus into RAW 264.7 cells. The inhibition
Externí odkaz:
https://doaj.org/article/f6fc86ae49c746149fb771df11a92062
Autor:
Elisabeth G. Vichaya, Josephine K. Darpolor, Phillip S. Gross, Jessica M. Molkentine, Daniel W. Vermeer, Paola D. Vermeer, John H. Lee, Cullen M. Taniguchi, Robert Dantzer
Publikováno v:
Brain, Behavior, and Immunity. 107:296-304
Persistent fatigue is a debilitating side effect that impacts a significant proportion of cancer survivors for which there is not yet an FDA-approved treatment. While certainly a multi-factorial problem, persistent fatigue could be due, in part, to a
Autor:
Yvette Robbins, Sarah Greene, Jay Friedman, Paul E Clavijo, Carter Van Waes, Kellsye P Fabian, Michelle R Padget, Houssein Abdul Sater, John H Lee, Patrick Soon-Shiong, James Gulley, Jeffrey Schlom, James W Hodge, Clint T Allen
Publikováno v:
eLife, Vol 9 (2020)
Failed T cell-based immunotherapies in the presence of genomic alterations in antigen presentations pathways may be overcome by NK cell-based immunotherapy. This approach may still be limited by the presence of immunosuppressive myeloid populations.
Externí odkaz:
https://doaj.org/article/c2df21fadf264488a0684e775401ddeb
Autor:
Jeffrey Schlom, James W Hodge, Clint T. Allen, Shahrooz Rabizadeh, Patrick Soon-Shiong, John H. Lee, Renee N. Donahue, Kristen Solocinski, Michelle R Padget, Kellsye P Fabian, Yvette Robbins
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Although immune checkpoint inhibitors have revolutionized cancer treatment, clinical benefit with this class of agents has been limited to a subset of patients. Hence, more effective means to target tumor cells that express immune checkpoi
Externí odkaz:
https://doaj.org/article/2cdc94ab811b4ee3a4c9aeb0ebba45c0
Autor:
Kathleen E. Fenerty, Michelle Padget, Benjamin Wolfson, Sofia R. Gameiro, Zhen Su, John H. Lee, Shahrooz Rabizadeh, Patrick Soon-Shiong, James W. Hodge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPi) prevent single-stranded DNA repair. Olaparib is a PARPi approved for the treatment of BRCA mutant ovarian and breast carcinoma. Emerging clinical data suggest a benefit of combining
Externí odkaz:
https://doaj.org/article/4f6eac2c2b1c4a31bc564e9a3f29ade8
Autor:
Marianna Madeo, Paul L. Colbert, Daniel W. Vermeer, Christopher T. Lucido, Jacob T. Cain, Elisabeth G. Vichaya, Aaron J. Grossberg, DesiRae Muirhead, Alex P. Rickel, Zhongkui Hong, Jing Zhao, Jill M. Weimer, William C. Spanos, John H. Lee, Robert Dantzer, Paola D. Vermeer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Tumors can induce axonogenesis which is commonly associated with worse outcomes. Here, the authors show that this phenomenon is mediated by cancer exosomes.
Externí odkaz:
https://doaj.org/article/aaa8e375f8d44392b380867c6849d0bc