Zobrazeno 1 - 10
of 882
pro vyhledávání: '"John H, Adams"'
Autor:
Sam Afoullouss, Ryan M. Young, Laurence K. Jennings, Jason Doyle, Karen Croke, Debora Livorsi, John H. Adams, Mark P. Johnson, Olivier P. Thomas, A. Louise Allcock
Publikováno v:
ACS Omega, Vol 9, Iss 40, Pp 41914-41922 (2024)
Externí odkaz:
https://doaj.org/article/e98a6bc1eccd4b76aa6927d83e7d51e0
Autor:
Brittany Hazzard, Juliana M. Sá, Haikel N. Bogale, Tales V. Pascini, Angela C. Ellis, Shuchi Amin, Jennifer S. Armistead, John H. Adams, Thomas E. Wellems, David Serre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Most Plasmodium vivax infections contain genetically distinct parasites, but the consequences of this polyclonality on the development of asexual parasites, their sexual differentiation, and their transmission remain unknown. We describe inf
Externí odkaz:
https://doaj.org/article/0a2b0dece0d746098ac2d4e0675fe134
Autor:
Wai Kwan Tang, Nichole D. Salinas, Surendra Kumar Kolli, Shulin Xu, Darya V. Urusova, Hirdesh Kumar, John R. Jimah, Pradeep Annamalai Subramani, Madison M. Ogbondah, Samantha J. Barnes, John H. Adams, Niraj H. Tolia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract CelTOS is a malaria vaccine antigen that is conserved in Plasmodium and other apicomplexan parasites and plays a role in cell-traversal. The structural basis and mechanisms of CelTOS-induced protective immunity to parasites are unknown. Here
Externí odkaz:
https://doaj.org/article/d0429fc0473748f896d3001e25c1ffd9
Autor:
Pongsakorn Thawornpan, Zulfa Zahra Salsabila, Piyawan Kochayoo, Tipanan Khunsri, Chayapat Malee, Kittikorn Wangriatisak, Chaniya Leepiyasakulchai, Francis Babila Ntumngia, John H Adams, Patchanee Chootong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 10, p e0012625 (2024)
BackgroundPlasmodium vivax is the dominant Plasmodium spp. causing malaria throughout tropical and sub-tropical countries. Humoral immunity is induced during P. vivax infection. However, data on longevity of antibody and memory B cell (MBC) responses
Externí odkaz:
https://doaj.org/article/63f22c5cc8ba4e96a36c2d9e0b408915
Autor:
Azhar Muneer, Swamy R. Adapa, Suzane Silbert, Kelly Scanlan, Harold Vore, Andrew Cannons, Andrea M. Morrison, Danielle Stanek, Carina Blackmore, John H. Adams, Kami Kim, Rays H.Y. Jiang, Liwang Cui
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 6, Pp 1214-1217 (2024)
During May–July 2023, a cluster of 7 patients at local hospitals in Florida, USA, received a diagnosis of Plasmodium vivax malaria. Whole-genome sequencing of the organism from 4 patients and phylogenetic analysis with worldwide representative P. v
Externí odkaz:
https://doaj.org/article/5eeae53dd91f43778ec4357fefe0d3b4
Autor:
Francis Babila Ntumngia, Surendra Kumar Kolli, Pradeep Annamalai Subramani, Samantha J. Barnes, Justin Nicholas, Madison M. Ogbondah, Brian B. Barnes, Nichole D. Salinas, Pongsakorn Thawornpan, Niraj H. Tolia, Patchanee Chootong, John H. Adams
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In Plasmodium vivax, the most studied vaccine antigens are aimed at blocking merozoite invasion of erythrocytes and disease development. Very few studies have evaluated pre-erythrocytic (PE) stage antigens. The P. vivax circumsporozoite prot
Externí odkaz:
https://doaj.org/article/d14402fce10d475e9b4b167329817cb1
Autor:
Justin Nicholas, Surendra Kumar Kolli, Pradeep Annamalai Subramani, Sai Lata De, Madison M. Ogbondah, Samantha J. Barnes, Francis Babila Ntumngia, John H. Adams
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Acquired functional inhibitory antibodies are one of several humoral immune mechanisms used to neutralize foreign pathogens. In vitro bioassays are useful tools for quantifying antibody-mediated inhibition and evaluating anti-para
Externí odkaz:
https://doaj.org/article/ef907aea9d314903925099b669db0dc3
Autor:
Chengqi Wang, Yibo Dong, Chang Li, Jenna Oberstaller, Min Zhang, Justin Gibbons, Camilla Valente Pires, Mianli Xiao, Lei Zhu, Rays H. Y. Jiang, Kami Kim, Jun Miao, Thomas D. Otto, Liwang Cui, John H. Adams, Xiaoming Liu
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Malaria remains one of the deadliest infectious diseases. Transcriptional regulation effects of noncoding variants in this unusual genome of malaria parasites remain elusive. We developed a sequence-based, ab initio deep learning framework,
Externí odkaz:
https://doaj.org/article/004e37fc75b5456aa0afc0c9d7b5baaa
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Knowledge of the diversity of invasion ligands in malaria parasites in endemic regions is essential to understand how natural selection influences genetic diversity of these ligands and their feasibility as possible targets for fu
Externí odkaz:
https://doaj.org/article/1a565ca9439b4b9ab56d7fcf965869ca
Autor:
Camilla Valente Pires, Debora Cassandra, Shulin Xu, Benoit Laleu, Jeremy N. Burrows, John H. Adams
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Malaria parasites have adaptive mechanisms to modulate their intracellular redox status to tolerate the enhanced oxidizing effects created by malaria fever, hemoglobinopathies and other stress conditions, including antimalaria drugs. Emergin
Externí odkaz:
https://doaj.org/article/76188a7284fa440fbb34f23d01b7d90d