Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John Groten"'
Autor:
Akanksha Roy, Arianna Tolone, Riet Hilhorst, John Groten, Tushar Tomar, François Paquet-Durand
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Inherited retinal diseases (IRDs) are a group of neurodegenerative disorders that lead to photoreceptor cell death and eventually blindness. IRDs are characterised by a high genetic heterogeneity, making it imperative to design mutation-inde
Externí odkaz:
https://doaj.org/article/78efcf27405940b8a50d8b999e7e43f9
Autor:
Evers, N.M.
The aim of the current thesis is to elucidate the role of estrogen receptor (ER)αand ERβin cell proliferation and apoptosis induced by estrogenic compounds. Special attention is paid to the importance of the receptor preference of the estrogenic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6fc0669602ed912083e98edfeb4d56dd
https://research.wur.nl/en/publications/factors-influencing-er-subtype-mediated-cell-proliferation-and-ap
https://research.wur.nl/en/publications/factors-influencing-er-subtype-mediated-cell-proliferation-and-ap
Autor:
Westerink, W.M.A.
In drug development, toxicity is an important factor for attrition, resulting in a failure rate of 30%-40%. Hepatotoxicity, nephrotoxicity, cardiovascular safety, reproduction toxicity, developmental toxicity (teratogenicity), genotoxicity and carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f6edb27ec9a1a017f855f2f663e40d65
https://research.wur.nl/en/publications/the-development-of-improved-and-new-in-vitro-assays-for-detecting
https://research.wur.nl/en/publications/the-development-of-improved-and-new-in-vitro-assays-for-detecting
Autor:
Schutte, M.E.
The transport of food ingredients across the intestinal epithelium is an important factor determining the absorption upon oral intake. Uptake of compounds in the intestine may be influenced by transport proteins such as the ATP binding cassette trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::de6a780078f95a1e029c731150082e45
https://research.wur.nl/en/publications/effect-of-mixtures-of-flavonoids-on-the-in-vitro-and-in-vivo-bioa
https://research.wur.nl/en/publications/effect-of-mixtures-of-flavonoids-on-the-in-vitro-and-in-vivo-bioa
Autor:
Heijne, W.H.M.
Toxicogenomics studies toxic effects of substances on organisms in relation to the composition of the genome. It applies the functional genomics technologies transcriptomics, proteomics and metabolomics that determine expression of the genes, protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2337c640a312f9213e7728a1a47f40c3
https://research.wur.nl/en/publications/toxicogenomics-applications-of-new-functional-genomics-technologi
https://research.wur.nl/en/publications/toxicogenomics-applications-of-new-functional-genomics-technologi
Autor:
Verwei, M.
The gap between actual intake and recommended intake of folate could be bridged by the consumption of fortified food products. Milk is considered as a potential food matrix for folate fortification in countries (such as theNetherlands) witha highmilk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::291cc7b1795ad57b97408b85cef415ad
http://resolver.tudelft.nl/uuid:1a390208-2e99-4e10-8270-b737d288d644
http://resolver.tudelft.nl/uuid:1a390208-2e99-4e10-8270-b737d288d644