Zobrazeno 1 - 10
of 14
pro vyhledávání: '"John Gosney"'
Publikováno v:
Cardiology Research and Practice, Vol 2011 (2011)
Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of
Externí odkaz:
https://doaj.org/article/0f819ef26bcf45eb9cd862fe04eac0b1
Publikováno v:
Lung Cancer. 178:S18-S19
Autor:
Chris Bell, John Gosney
Publikováno v:
Lung Cancer. 178:S40-S41
Autor:
Alexander Haragan, John Gosney
Publikováno v:
Lung Cancer. 178:S2
Autor:
A.M. Quinn, R. Bowden, John Gosney, Fiona H Blackhall, R. Bloor, Paul N. Bishop, C. Harreld, A. Moss, A. Paiva-Correia, H. Doran, Phil Crosbie, A. Montero, Anshuman Chaturvedi, Yvonne Summers, Leena Dennis Joseph, S. Forrest, C. A. M. McNulty, Phillipe Taniere
Publikováno v:
Journal of Thoracic Oncology. 13:S761-S763
Autor:
Merdol Ibrahim, Marianne Nicolson, Andrew G. Nicholson, Richard Booton, Paul Cane, Keith M. Kerr, Conrad R. Lewanski, Neal Navani, Yvonne Summers, Rohit Lal, Ian A Cree, John Gosney
Publikováno v:
Histopathology. 69:177-186
A new approach to the management of non-small-cell lung cancer (NSCLC) has recently emerged that works by manipulating the immune checkpoint controlled by programmed death receptor 1 (PD-1) and its ligand programmed death ligand 1 (PD-L1). Several dr
Autor:
Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley, Andrew J. Rowan, Thomas B.K. Watkins, Gareth A. Wilson, Nicolai J. Birkbak, Selvaraju Veeriah, Peter Van Loo, Javier Herrero, Charles Swanton, Mariam Jamal-Hanjani, Seema Shafi, Justyna Czyzewska-Khan, Diana Johnson, Joanne Laycock, Leticia Bosshard-Carter, Pat Gorman, Robert E. Hynds, Gareth Wilson, Stuart Horswell, Richard Mitter, Mickael Escudero, Aengus Stewart, Andrew Rowan, Hang Xu, Samra Turajlic, Crispin Hiley, Christopher Abbosh, Jacki Goldman, Richard Kevin Stone, Tamara Denner, Nik Matthews, Greg Elgar, Sophia Ward, Marta Costa, Sharmin Begum, Ben Phillimore, Tim Chambers, Emma Nye, Sofia Graca, Maise Al Bakir, Kroopa Joshi, Andrew Furness, Assma Ben Aissa, Yien Ning Sophia Wong, Andy Georgiou, Sergio Quezada, John A. Hartley, Helen L. Lowe, David Lawrence, Martin Hayward, Nikolaos Panagiotopoulos, Shyam Kolvekar, Mary Falzon, Elaine Borg, Teresa Marafioti, Celia Simeon, Gemma Hector, Amy Smith, Marie Aranda, Marco Novelli, Dahmane Oukrif, Sam M. Janes, Ricky Thakrar, Martin Forster, Tanya Ahmad, Siow Ming Lee, Dionysis Papadatos-Pastos, Dawn Carnell, Ruheena Mendes, Jeremy George, Neal Navani, Asia Ahmed, Magali Taylor, Junaid Choudhary, Yvonne Summers, Raffaele Califano, Paul Taylor, Rajesh Shah, Piotr Krysiak, Kendadai Rammohan, Eustace Fontaine, Richard Booton, Matthew Evison, Phil Crosbie, Stuart Moss, Faiza Idries, Leena Joseph, Paul Bishop, Anshuman Chaturved, Anne Marie Quinn, Helen Doran, Angela Leek, Phil Harrison, Katrina Moore, Rachael Waddington, Juliette Novasio, Fiona Blackhall, Jane Rogan, Elaine Smith, Caroline Dive, Jonathan Tugwood, Ged Brady, Dominic G. Rothwell, Francesca Chemi, Jackie Pierce, Sakshi Gulati, Babu Naidu, Gerald Langman, Simon Trotter, Mary Bellamy, Hollie Bancroft, Amy Kerr, Salma Kadiri, Joanne Webb, Gary Middleton, Madava Djearaman, Dean Fennell, Jacqui A. Shaw, John Le Quesne, David Moore, Apostolos Nakas, Sridhar Rathinam, William Monteiro, Hilary Marshall, Louise Nelson, Jonathan Bennett, Joan Riley, Lindsay Primrose, Luke Martinson, Girija Anand, Sajid Khan, Anita Amadi, Marianne Nicolson, Keith Kerr, Shirley Palmer, Hardy Remmen, Joy Miller, Keith Buchan, Mahendran Chetty, Lesley Gomersall, Jason Lester, Alison Edwards, Fiona Morgan, Haydn Adams, Helen Davies, Malgorzata Kornaszewska, Richard Attanoos, Sara Lock, Azmina Verjee, Mairead MacKenzie, Maggie Wilcox, Harriet Bell, Allan Hackshaw, Yenting Ngai, Sean Smith, Nicole Gower, Christian Ottensmeier, Serena Chee, Benjamin Johnson, Aiman Alzetani, Emily Shaw, Eric Lim, Paulo De Sousa, Monica Tavares Barbosa, Alex Bowman, Simon Jordan, Alexandra Rice, Hilgardt Raubenheimer, Chiara Proli, Maria Elena Cufari, John Carlo Ronquillo, Angela Kwayie, Harshil Bhayani, Morag Hamilton, Yusura Bakar, Natalie Mensah, Lyn Ambrose, Anand Devaraj, Silviu Buderi, Jonathan Finch, Leire Azcarate, Hema Chavan, Sophie Green, Hillaria Mashinga, Andrew G. Nicholson, Kelvin Lau, Michael Sheaff, Peter Schmid, John Conibear, Veni Ezhil, Babikir Ismail, Melanie Irvin-sellers, Vineet Prakash, Peter Russell, Teresa Light, Tracey Horey, Sarah Danson, Jonathan Bury, John Edwards, Jennifer Hill, Sue Matthews, Yota Kitsanta, Kim Suvarna, Patricia Fisher, Allah Dino Keerio, Michael Shackcloth, John Gosney, Pieter Postmus, Sarah Feeney, Julius Asante-Siaw, Hugo J.W.L. Aerts, Stefan Dentro, Christophe Dessimoz
Publikováno v:
McGranahan, N, Rosenthal, R, Hiley, CT, Rowan, AJ, Watkins, TBK, Wilson, GA, Birkbak, NJ, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Blackhall, F & Crosbie, P 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell . https://doi.org/10.1016/j.cell.2017.10.001
Cell, vol. 171, no. 6, pp. 1259-1271.e11
McGranahan, N, Rosenthal, R, Hiley, C T, Rowan, A J, Watkins, T B K, Wilson, G A, Birkbak, N J, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Jamal-Hanjani, M, Shafi, S, Czyzewska-Khan, J, Johnson, D, Laycock, J, Bosshard-Carter, L, Gorman, P, Hynds, R E, Wilson, G, Horswell, S, Mitter, R, Escudero, M, Stewart, A, Rowan, A, Xu, H, Turajlic, S, Abbosh, C, Goldman, J, Stone, R K, Denner, T, Matthews, N, Elgar, G, Ward, S, Costa, M, Begum, S, Phillimore, B, Chambers, T, Nye, E, Graca, S, Al Bakir, M, Joshi, K, Furness, A, Ben Aissa, A, Wong, Y N S, Georgiou, A, Quezada, S, Hartley, J A, Lowe, H L, Lawrence, D, Hayward, M, Panagiotopoulos, N, Kolvekar, S, Falzon, M, Borg, E, Marafioti, T, Simeon, C, Hector, G, Smith, A, Aranda, M, Novelli, M, Oukrif, D, Janes, S M, Thakrar, R, Forster, M, Ahmad, T, Lee, S M, Papadatos-Pastos, D, Carnell, D, Mendes, R, George, J, Navani, N, Ahmed, A, Taylor, M, Choudhary, J, Summers, Y, Califano, R, Taylor, P, Shah, R, Krysiak, P, Rammohan, K, Fontaine, E, Booton, R, Evison, M, Crosbie, P, Moss, S, Idries, F, Joseph, L, Bishop, P, Chaturved, A, Quinn, A M, Doran, H, Leek, A, Harrison, P, Moore, K, Waddington, R, Novasio, J, Blackhall, F, Rogan, J, Smith, E, Dive, C, Tugwood, J, Brady, G, Rothwell, D G, Chemi, F, Pierce, J, Gulati, S, Naidu, B, Langman, G, Trotter, S, Bellamy, M, Bancroft, H, Kerr, A, Kadiri, S, Webb, J, Middleton, G, Djearaman, M, Fennell, D, Shaw, J A, Le Quesne, J, Moore, D, Nakas, A, Rathinam, S, Monteiro, W, Marshall, H, Nelson, L, Bennett, J, Riley, J, Primrose, L, Martinson, L, Anand, G, Khan, S, Amadi, A, Nicolson, M, Kerr, K, Palmer, S, Remmen, H, Miller, J, Buchan, K, Chetty, M, Gomersall, L, Lester, J, Edwards, A, Morgan, F, Adams, H, Davies, H, Kornaszewska, M, Attanoos, R, Lock, S, Verjee, A, MacKenzie, M, Wilcox, M, Bell, H, Hackshaw, A, Ngai, Y, Smith, S, Gower, N, Ottensmeier, C, Chee, S, Johnson, B, Alzetani, A, Shaw, E, Lim, E, De Sousa, P, Barbosa, M T, Bowman, A, Jordan, S, Rice, A, Raubenheimer, H, Proli, C, Cufari, M E, Ronquillo, J C, Kwayie, A, Bhayani, H, Hamilton, M, Bakar, Y, Mensah, N, Ambrose, L, Devaraj, A, Buderi, S, Finch, J, Azcarate, L, Chavan, H, Green, S, Mashinga, H, Nicholson, A G, Lau, K, Sheaff, M, Schmid, P, Conibear, J, Ezhil, V, Ismail, B, Irvin-sellers, M, Prakash, V, Russell, P, Light, T, Horey, T, Danson, S, Bury, J, Edwards, J, Hill, J, Matthews, S, Kitsanta, Y, Suvarna, K, Fisher, P, Keerio, A D, Shackcloth, M, Gosney, J, Postmus, P, Feeney, S, Asante-Siaw, J, Aerts, H J W L, Dentro, S & Dessimoz, C 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell, vol. 171, no. 6, pp. 1259-1271.e11 . https://doi.org/10.1016/j.cell.2017.10.001
Cell, vol. 171, no. 6, pp. 1259-1271.e11
McGranahan, N, Rosenthal, R, Hiley, C T, Rowan, A J, Watkins, T B K, Wilson, G A, Birkbak, N J, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Jamal-Hanjani, M, Shafi, S, Czyzewska-Khan, J, Johnson, D, Laycock, J, Bosshard-Carter, L, Gorman, P, Hynds, R E, Wilson, G, Horswell, S, Mitter, R, Escudero, M, Stewart, A, Rowan, A, Xu, H, Turajlic, S, Abbosh, C, Goldman, J, Stone, R K, Denner, T, Matthews, N, Elgar, G, Ward, S, Costa, M, Begum, S, Phillimore, B, Chambers, T, Nye, E, Graca, S, Al Bakir, M, Joshi, K, Furness, A, Ben Aissa, A, Wong, Y N S, Georgiou, A, Quezada, S, Hartley, J A, Lowe, H L, Lawrence, D, Hayward, M, Panagiotopoulos, N, Kolvekar, S, Falzon, M, Borg, E, Marafioti, T, Simeon, C, Hector, G, Smith, A, Aranda, M, Novelli, M, Oukrif, D, Janes, S M, Thakrar, R, Forster, M, Ahmad, T, Lee, S M, Papadatos-Pastos, D, Carnell, D, Mendes, R, George, J, Navani, N, Ahmed, A, Taylor, M, Choudhary, J, Summers, Y, Califano, R, Taylor, P, Shah, R, Krysiak, P, Rammohan, K, Fontaine, E, Booton, R, Evison, M, Crosbie, P, Moss, S, Idries, F, Joseph, L, Bishop, P, Chaturved, A, Quinn, A M, Doran, H, Leek, A, Harrison, P, Moore, K, Waddington, R, Novasio, J, Blackhall, F, Rogan, J, Smith, E, Dive, C, Tugwood, J, Brady, G, Rothwell, D G, Chemi, F, Pierce, J, Gulati, S, Naidu, B, Langman, G, Trotter, S, Bellamy, M, Bancroft, H, Kerr, A, Kadiri, S, Webb, J, Middleton, G, Djearaman, M, Fennell, D, Shaw, J A, Le Quesne, J, Moore, D, Nakas, A, Rathinam, S, Monteiro, W, Marshall, H, Nelson, L, Bennett, J, Riley, J, Primrose, L, Martinson, L, Anand, G, Khan, S, Amadi, A, Nicolson, M, Kerr, K, Palmer, S, Remmen, H, Miller, J, Buchan, K, Chetty, M, Gomersall, L, Lester, J, Edwards, A, Morgan, F, Adams, H, Davies, H, Kornaszewska, M, Attanoos, R, Lock, S, Verjee, A, MacKenzie, M, Wilcox, M, Bell, H, Hackshaw, A, Ngai, Y, Smith, S, Gower, N, Ottensmeier, C, Chee, S, Johnson, B, Alzetani, A, Shaw, E, Lim, E, De Sousa, P, Barbosa, M T, Bowman, A, Jordan, S, Rice, A, Raubenheimer, H, Proli, C, Cufari, M E, Ronquillo, J C, Kwayie, A, Bhayani, H, Hamilton, M, Bakar, Y, Mensah, N, Ambrose, L, Devaraj, A, Buderi, S, Finch, J, Azcarate, L, Chavan, H, Green, S, Mashinga, H, Nicholson, A G, Lau, K, Sheaff, M, Schmid, P, Conibear, J, Ezhil, V, Ismail, B, Irvin-sellers, M, Prakash, V, Russell, P, Light, T, Horey, T, Danson, S, Bury, J, Edwards, J, Hill, J, Matthews, S, Kitsanta, Y, Suvarna, K, Fisher, P, Keerio, A D, Shackcloth, M, Gosney, J, Postmus, P, Feeney, S, Asante-Siaw, J, Aerts, H J W L, Dentro, S & Dessimoz, C 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell, vol. 171, no. 6, pp. 1259-1271.e11 . https://doi.org/10.1016/j.cell.2017.10.001
Immune evasion is a hallmark of cancer. Losing the ability to present neoantigens through human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the polymorphic nature of the locus has precluded accurate HLA copy-number analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a275b5e6604203ea0560773e9e9dacd
https://research.manchester.ac.uk/en/publications/55c31c82-3f24-435d-bb77-3fb2c6170a8f
https://research.manchester.ac.uk/en/publications/55c31c82-3f24-435d-bb77-3fb2c6170a8f
Autor:
I. Marondel, Jens Christian Sørensen, Buge Oz, Juergen Wolf, Lukas Bubendorf, E.J.M. Speel, Xavier Durando, Annemieke C. Hiemstra, A-M.C. Dingemans, M.A. van der Drift, Reinhard Büttner, N. Akyurek, Kim Monkhorst, Idris Bahce, M. Looijen Salomon, Patrick Pauwels, Wim Timens, Birgit I. Lissenberg-Witte, S.M.S. Samii, Birgit Weynand, Frédérique Penault-Llorca, Birgit Guldhammer Skov, Ed Schuuring, S.P. Finn, Erik Thunnissen, Sayed M.S. Hashemi, F. Duplaquet, John Gosney, Egbert F. Smit, Anders Mellemgaard, S. Duin, J. De Langen, M. van den Heuvel, Pieter E. Postmus
Publikováno v:
Journal of Thoracic Oncology, 13(10), S452-S452. International Association for the Study of Lung Cancer
Thunnissen, E, Lissenberg-Witte, B, Van Den Heuvel, M, Monkhorst, K, Skov, B, Sorensen, J, Mellemgaard, A, Dingemans, A, Speel, E, De Langen, J, Hashemi, S, Bahce, I, Van Der Drift, M, Büttner, R, Looijen Salomon, M, Gosney, J, Postmus, P E, Samii, S, Duplaquet, F, Weynand, B, Durando, X, Penault-Llorca, F, Finn, S, Oz, B, Akyurek, N, Wolf, J, Bubendorf, L, Hiemstra, A, Duin, S, Marondel, I, Timens, W, Schuuring, E, Pauwels, P & Smit, E 2018, ' MA26.06 Crizotinib-Treated ALK Immunopositive Metastasized NSCLC is Associated with an Unfavorable Prognosis when FISH Negative ', Journal of Thoracic Oncology, vol. 13, no. 10, pp. S452-S452 . https://doi.org/10.1016/j.jtho.2018.08.542
Thunnissen, E, Lissenberg-Witte, B, Van Den Heuvel, M, Monkhorst, K, Skov, B, Sorensen, J, Mellemgaard, A, Dingemans, A, Speel, E, De Langen, J, Hashemi, S, Bahce, I, Van Der Drift, M, Büttner, R, Looijen Salomon, M, Gosney, J, Postmus, P E, Samii, S, Duplaquet, F, Weynand, B, Durando, X, Penault-Llorca, F, Finn, S, Oz, B, Akyurek, N, Wolf, J, Bubendorf, L, Hiemstra, A, Duin, S, Marondel, I, Timens, W, Schuuring, E, Pauwels, P & Smit, E 2018, ' MA26.06 Crizotinib-Treated ALK Immunopositive Metastasized NSCLC is Associated with an Unfavorable Prognosis when FISH Negative ', Journal of Thoracic Oncology, vol. 13, no. 10, pp. S452-S452 . https://doi.org/10.1016/j.jtho.2018.08.542
Background Metastasized NSCLC with an ALK fusion are sensitive to a range of tyrosine kinase inhibitors. ALK-positive NSCLC has been identified in the pivotal phase III trial with fluorescence in situ hybridization (ALK FISH+). These tumors are also
Autor:
Margaret Burke, M A den Bakker, Andrew G. Nicholson, Bruce Addis, Ju Ee Seet, Hannah Monaghan, Sabine Pomplun, G Langman, E T Verghese, A Rice, A Hussein, Doris Rassl, S K Suvarna, Sten P. Willemsen, Keith M. Kerr, A Campbell, P Bishop, John Gosney, B Corrin
Publikováno v:
Histopathology, 53(2), 218-223. Wiley-Blackwell Publishing Ltd
Aims: To test the reproducibility of the current World Health Organization (WHO) classification of thymic epithelial tumours and to determine the level of interobserver variation within a group of pathologists, all with experience and expertise in th
Publikováno v:
Radiologia Brasileira, Vol 41, Iss 6, Pp 419-421 (2008)
We describe imaging findings of a oesophageal liposarcoma in a 66 year old man. The computed tomography scan was performed after a chest radiograph showed a large posterior mediastinal mass. Oesophageal liposarcomas are rare tumours. They can achieve