Zobrazeno 1 - 10
of 90
pro vyhledávání: '"John Gittins"'
Autor:
Roger H. Mitchell, John Gittins
Publikováno v:
Lithos. :106861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d9034a247aa8dc8113eb07895ee35c
https://doi.org/10.1016/j.lithos.2022.106861
https://doi.org/10.1016/j.lithos.2022.106861
Publikováno v:
Practical Medical Physics ISBN: 9781315142425
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5487034e2927e0e692d5b87945323b
https://doi.org/10.1201/9781315142425-6-8
https://doi.org/10.1201/9781315142425-6-8
Autor:
Anne-Marie Oreskovich, John Gittins
Publikováno v:
International Journal of Economics, Finance and Management Sciences. 9:16
The paper begins by reviewing the available procedures for measuring value and risk in pharmaceutical research projects. These include Net Present Value (NPV) and its variance, Real Options Valuation (ROV), the Capital Asset Pricing Model (CAPM), Val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1936a79755b91f859352b8495ddaef86
https://doi.org/10.11648/j.ijefm.20210901.13
https://doi.org/10.11648/j.ijefm.20210901.13
Autor:
John Gittins, Shrinivas G. Viladkar
Publikováno v:
Journal of the Geological Society of India. 87:709-715
The Siriwasan carbonatite-sill along with associated alkaline rocks and fenites is located about 10 km north of the well-known Amba Dongar carbonatite-alkaline rocks diatreme, in the Chhota Udaipur carbonatite-alkaline province. Carbonatite has intru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::087734e757ffb0e595824c711f3de879
https://doi.org/10.1007/s12594-016-0443-4
https://doi.org/10.1007/s12594-016-0443-4
Autor:
John Gittins, Anne-Marie Oreskovich
Publikováno v:
R&D Management. 46:900-913
This paper reviews the need for risk management in pharmaceutical industry research and development and the analytical procedures available for that purpose. These are shown to be inadequate. We propose two new measures of risk which are illustrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7d833a3058f79c22b23002c54b3746f
https://doi.org/10.1111/radm.12200
https://doi.org/10.1111/radm.12200
Autor:
Takashi Kikuchi, John Gittins
Publikováno v:
Journal of the Royal Statistical Society Series C: Applied Statistics. 59:875-888
Summary Cluster randomized clinical trials are increasingly popular to evaluate disease control interventions for communities. In these trials health interventions are allocated randomly to complete clusters or groups rather than to individual subjec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d029b12f69d559605c5366f270530497
https://doi.org/10.1111/j.1467-9876.2010.00732.x
https://doi.org/10.1111/j.1467-9876.2010.00732.x
Autor:
Takashi Kikuchi, John Gittins
Publikováno v:
Statistical Methods in Medical Research. 20:389-400
The behavioural Bayes approach to sample size determination for clinical trials assumes that the number of subsequent patients switching to a new drug from the current drug depends on the strength of the evidence for efficacy and safety that was obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536181509a43011337b140e9dc35346c
https://doi.org/10.1177/0962280209358131
https://doi.org/10.1177/0962280209358131
Autor:
Takashi Kikuchi, John Gittins
Publikováno v:
Statistics in Medicine. 28:2293-2306
It is necessary for the calculation of sample size to achieve the best balance between the cost of a clinical trial and the possible benefits from a new treatment. Gittins and Pezeshk developed an innovative (behavioral Bayes) approach, which assumes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b066a58ee168bbafab7d30e771ff99
https://doi.org/10.1002/sim.3630
https://doi.org/10.1002/sim.3630
Autor:
John Gittins, Chesda Udommongkol, Emma M.L. Chung, Chloe V. Long, Brian R. Chambers, David H. Evans, Kumar V. Ramnarine, Glen C. Bush
Publikováno v:
Stroke. 40:648-651
Background and Purpose— Small-vessel knock is a recently reported Doppler ultrasound finding that has been identified in patients with cerebral ischemia. It has been hypothesized that knock-type signals are linked to the presence of either small-ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae3c0364d100f4c22fab06e283f41db3
https://doi.org/10.1161/strokeaha.108.516880
https://doi.org/10.1161/strokeaha.108.516880
Autor:
John Gittins, Jiun-Yu Yu
Publikováno v:
European Journal of Operational Research. 189:459-475
The pharmaceutical industry is highly competitive, and the discovery and development of new drugs is extremely expensive and time consuming. This paper is a contribution to the task of improving the effectiveness of pre-clinical research. Our model i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b996964fcd394af67c020aff2f597f8
https://doi.org/10.1016/j.ejor.2007.05.023
https://doi.org/10.1016/j.ejor.2007.05.023