Zobrazeno 1 - 10
of 26
pro vyhledávání: '"John G. Ward"'
Autor:
Philip G. Humphreys, John G. Ward, Christopher A. J. Brierley, David M. Hodgson, Steven M. Miles
Publikováno v:
The Journal of Organic Chemistry. 72:10009-10021
The scope of dimerization and isomerization reactions of alpha-lithiated terminal aziridines is detailed. Regio- and stereoselective deprotonation of simple terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide (LTMP) or lithium dicyclohexyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5e28fdcc7544fa5d6b616b20feaea0
https://doi.org/10.1021/jo701901t
https://doi.org/10.1021/jo701901t
Publikováno v:
Organic Letters. 7:1153-1156
[reaction: see text] Regio- and stereoselective deprotonation of N-Bus (Bus = tert-butylsulfonyl)-protected terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide generates a nonstabilized (H-substituted) aziridinyl anion that undergoes in si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93ef053362fc0ffbea25e5578671682
https://doi.org/10.1021/ol050060f
https://doi.org/10.1021/ol050060f
Publikováno v:
Genetics. 140:989-1005
Conjugation fails postzygotically after mating of Tetrahymena cells that have wild-type parental macronuclei but harbor noncomplementing nullisomic parental germline deficiencies. Failures begin shortly after formation of the new macronuclear precurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04af9ce70e18665361e8401a5371ca60
https://doi.org/10.1093/genetics/140.3.989
https://doi.org/10.1093/genetics/140.3.989
Autor:
Steven M. Miles, Christopher A. J. Brierley, Philip G. Humphreys, John G. Ward, David M. Hodgson
Publikováno v:
ChemInform. 39
The scope of dimerization and isomerization reactions of α-lithiated terminal aziridines is detailed. Regio- and stereoselective deprotonation of simple terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide (LTMP) or lithium dicyclohexylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e073cd8bf8af3131e5cdda68ad9fcb
https://doi.org/10.1002/chin.200818094
https://doi.org/10.1002/chin.200818094
Autor:
Eggleston Ds, CP Downes, Martin Jones, C.H. Macphee, Kishore K. Rana, Rodney C. Young, John G. Ward
Publikováno v:
Journal of Medicinal Chemistry. 33:641-646
A new and convenient method for the preparation of the four stereoisomers of dihexadecanoyl phosphatidylinositol has been developed. An enantiomeric pair of acid-labile, pentaprotected myo-inositol building blocks was synthesized in high yield and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76041d1448c00dcb03f05a241d4f85c
https://doi.org/10.1021/jm00164a027
https://doi.org/10.1021/jm00164a027
Publikováno v:
Angewandte Chemie (International ed. in English). 46(13)
(Chemical Equation Presented) Benefiting from deprotection: Lithium 2,2,6,6-tetramethylpiperidide induces N-Boc or N-phosphonate terminal aziridines to undergo regio- and stereoselective N-to-C migration of the protecting group, giving synthetically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6157cfc8bad746aa1a4e57e2e4a05e1d
http://ora.ox.ac.uk/objects/uuid:edd248b0-40cd-4562-9e34-824497cba474
http://ora.ox.ac.uk/objects/uuid:edd248b0-40cd-4562-9e34-824497cba474
Publikováno v:
Organic letters. 8(5)
Regio- and stereoselective deprotonation of bishomoallylic terminal N-Bus (Bus=tert-butylsulfonyl)-protected aziridines generate aziridinyl anions that undergo diastereoselective intramolecular cyclopropanation giving trans-2-aminobicyclo[3.1.0]hexan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33889ab493157aadf6946642beb87fe4
http://ora.ox.ac.uk/objects/uuid:d9991407-228b-460d-8432-022af871d259
http://ora.ox.ac.uk/objects/uuid:d9991407-228b-460d-8432-022af871d259
Publisher Summary Microinjection has proved to be a powerful experimental tool used to introduce macromolecules into cells. The method is widely used for DNA-mediated transformation of diverse organisms including ciliates, nematodes, insects, and mam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b5e87697f1847814c31fe1301f61716
https://doi.org/10.1016/s0091-679x(08)61551-4
https://doi.org/10.1016/s0091-679x(08)61551-4
Publikováno v:
Chromosoma. 106(4)
In the ciliated protozoan, Tetrahymena thermophila, the diploid germinal micronucleus contains two allelic copies of the gene for ribosomal RNA (rDNA). During genesis of new somatic macronuclei the germline rDNA gene is excised by developmentally pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deaf0049a8b7aeb623b6e45c91c8d40
https://pubmed.ncbi.nlm.nih.gov/9254725
https://pubmed.ncbi.nlm.nih.gov/9254725
Autor:
John G. Ward, Glenn Herrick
Publikováno v:
Developmental biology. 173(1)
DuringTetrahymena thermophilaconjugation, new somatic macronuclei develop from a common zygotic nucleus derived from meiotic products of the germline, and the old parental somatic nucleus is destroyed. The transcription inhibitor actinomycin D disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42e76d7a9319759f77e917ed240dfa0
https://pubmed.ncbi.nlm.nih.gov/8575619
https://pubmed.ncbi.nlm.nih.gov/8575619