Zobrazeno 1 - 10
of 28
pro vyhledávání: '"John G. Neilan"'
Publikováno v:
Vaccines, Vol 11, Iss 2, p 386 (2023)
We evaluated four DNA vaccine candidates for their ability to produce virus-like particles (VLPs) and elicit a protective immune response against Foot-and-mouth disease virus (FMDV) in cattle. Two traditional DNA plasmids and two DNA minicircle const
Externí odkaz:
https://doaj.org/article/dd14feae653b47d1a3a5105407f7aea6
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1506 (2022)
To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an experimental, plasmid-based, virus-like particle (VLP) vaccine. Inclusion of the FMDV viropor
Externí odkaz:
https://doaj.org/article/72b0155f019b4b1983c7c3869fb01b8d
Autor:
Jessica Mason, Victoria Primavera, Lauren Martignette, Benjamin Clark, Jose Barrera, Janine Simmons, William Hurtle, John G. Neilan, Michael Puckette
Publikováno v:
Viruses, Vol 14, Iss 9, p 1875 (2022)
Senecavirus A (SVA) is a member of the family Picornaviridae and enzootic in domestic swine. SVA can induce vesicular lesions that are clinically indistinguishable from Foot-and-mouth disease, a major cause of global trade barriers and agricultural p
Externí odkaz:
https://doaj.org/article/0c2cc4abed9c4713ac533985a904a09b
Autor:
John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman, David A. Brake
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-9 (2018)
Abstract Background A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previously immunized w
Externí odkaz:
https://doaj.org/article/d44e40a861c547708a6f63307b3c82ea
Publikováno v:
BMC Biotechnology, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity. We sought to simultaneously quantit
Externí odkaz:
https://doaj.org/article/45b4973632914b68b01e6a723567bb7a
Autor:
Laslo Zsak, John G. Neilan
Publikováno v:
The Scientific World Journal, Vol 2, Pp 1186-1195 (2002)
A number of viruses have evolved antiapoptotic mechanisms to promote infected-cell survival, either to ensure efficient productive viral replication or to promote long-term survival of virus-infected cells. Recent studies identified critical African
Externí odkaz:
https://doaj.org/article/3749bc23e69046119d50d7aa819b20f0
Publikováno v:
Journal of Applied Microbiology
Aims Develop an effective laboratory method to consistently recover viral loads from porous concrete coupons sufficient for disinfectant efficacy testing. Investigate the role of concrete matrix pH on the recovery of foot-and-mouth disease virus (FMD
Autor:
Emily M. Forzono, Benjamin A. Clark, John G. Neilan, Erica Martel, Michael Puckette, Richard Kurker
Publikováno v:
Journal of General Virology. 100:446-456
The production of experimental molecular vaccines against foot-and-mouth disease virus utilizes the viral encoded 3C protease for processing of the P1 polyprotein. Expression of wild type 3C protease is detrimental to host cells. The molecular vaccin
Autor:
Max V. Rasmussen, William Hurtle, Mariceny Zurita, Damodar Ettyreddy, Christopher Schutta, Bruce G. Harper, David A. Brake, Barbara J. Kamicker, Melia Pisano, Douglas E. Brough, John G. Neilan, Bryan T. Butman, Carla Bravo de Rueda, José Barrera
Publikováno v:
Vaccine. 36:7345-7352
We investigated the serotype- and topotype versatility of a replication-deficient human adenovirus serotype 5 vectored foot-and-mouth disease (FMD) vaccine platform (AdtFMD). Sixteen AdtFMD recombinant subunit monovalent vaccines targeting twelve dis
Autor:
Erica Martel, John G. Neilan, Melia Pisano, José Barrera, Michael Puckette, Lauren Martignette, William Hurtle, Chungwon J. Chung, Mariceny Zurita, Jacob Rutherford
Publikováno v:
Journal of immunological methods. 487
This report covers the methodology for generation of stable heterohybridoma clones producing Foot-and-mouth disease virus (FMDV) reactive porcine monoclonal antibodies (mAbs). Swine received five inoculations of an inactivated O1 Manisa FMDV vaccine