Zobrazeno 1 - 10
of 355
pro vyhledávání: '"John G. Jones"'
Autor:
Ana Reis-Costa, Getachew D. Belew, Ivan Viegas, Ludgero C. Tavares, Maria João Meneses, Bárbara Patrício, Amalia Gastaldelli, Maria Paula Macedo, John G. Jones
Publikováno v:
Nutrients, Vol 16, Iss 14, p 2186 (2024)
Background: In MASLD (formerly called NAFLD) mouse models, oversupply of dietary fat and sugar is more lipogenic than either nutrient alone. Fatty acids suppress de novo lipogenesis (DNL) from sugars, while DNL inhibits fatty acid oxidation. How such
Externí odkaz:
https://doaj.org/article/d8e46f93d6b448c58f4acd8a3b0a6005
Autor:
Vitor Ferreira, Cintia Folgueira, María García-Altares, Maria Guillén, Mónica Ruíz-Rosario, Giada DiNunzio, Irma Garcia-Martinez, Rosa Alen, Christoph Bookmeyer, John G. Jones, Juan C. Cigudosa, Pilar López-Larrubia, Xavier Correig-Blanchar, Roger J. Davis, Guadalupe Sabio, Patricia Rada, Ángela M. Valverde
Publikováno v:
Redox Biology, Vol 63, Iss , Pp 102741- (2023)
Olanzapine (OLA), a widely used second-generation antipsychotic (SGA), causes weight gain and metabolic alterations when administered orally to patients. Recently, we demonstrated that, contrarily to the oral treatment which induces weight gain, OLA
Externí odkaz:
https://doaj.org/article/df70da12cc2d45ac97775fe0e1db3edf
Autor:
Margarida Coelho, João Capela, Vera M. Mendes, João Pacheco, Margarida Sá Fernandes, Isabel Amendoeira, John G. Jones, Luís Raposo, Bruno Manadas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 376 (2023)
Thyroid cancer is a common malignancy of the endocrine system. Nodules are routinely evaluated for malignancy risk by fine needle aspiration biopsy (FNAB), and in cases such as follicular lesions, differential diagnosis between benign and malignant n
Externí odkaz:
https://doaj.org/article/d617590ba86b4e7499eebf50092fe0a5
Autor:
Margarida Coelho, João Capela, Sandra I. Anjo, João Pacheco, Margarida Sá Fernandes, Isabel Amendoeira, John G. Jones, Luís Raposo, Bruno Manadas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14542 (2023)
Differentiated thyroid cancer is the most common malignancy of the endocrine system. Although most thyroid nodules are benign, given the high incidence of thyroid nodules in the population, it is important to understand the differences between benign
Externí odkaz:
https://doaj.org/article/dc46729911d845778221c331eb3c22d2
Autor:
Ricardo Amorim, Inês C.M. Simões, José Teixeira, Fernando Cagide, Yaiza Potes, Pedro Soares, Adriana Carvalho, Ludgero C. Tavares, Sofia Benfeito, Susana P. Pereira, Rui F. Simões, Agnieszka Karkucinska-Wieckowska, Ivan Viegas, Sylwia Szymanska, Michał Dąbrowski, Justyna Janikiewicz, Teresa Cunha-Oliveira, Agnieszka Dobrzyń, John G. Jones, Fernanda Borges, Mariusz R. Wieckowski, Paulo J. Oliveira
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102400- (2022)
Non-alcoholic fatty liver disease (NAFLD) is a health concern affecting 24% of the population worldwide. Although the pathophysiologic mechanisms underlying disease are not fully clarified, mitochondrial dysfunction and oxidative stress are key playe
Externí odkaz:
https://doaj.org/article/f512c15d747348f8a5a50917b0e4613a
Autor:
David L. Lentz, Trinity L. Hamilton, Nicholas P. Dunning, John G. Jones, Kathryn Reese-Taylor, Armando Anaya Hernández, Debra S. Walker, Eric J. Tepe, Christopher Carr, Jeff L. Brewer, Thomas Ruhl, Stephanie A. Meyers, Mariana Vazquez, Alex Golden, Alison A. Weiss
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
Yaxnohcah was a major city of the ancient Maya world, especially during the Preclassic period (1000 BCE–200 CE). Data from excavations provide important insights into the interactions between the ancient inhabitants and its surrounding Neotropical
Externí odkaz:
https://doaj.org/article/8a0b6dbb18704505b25d4c415f6b45e8
Publikováno v:
Nutrients, Vol 15, Iss 9, p 2097 (2023)
Describing diet-related effects on the gut microbiome is essential for understanding its interactions with fat and/or sugar-rich diets to promote obesity-related metabolic diseases. Here, we sequenced the V3-V4 hypervariable region of the bacterial 1
Externí odkaz:
https://doaj.org/article/a64c9907dc71486588a61207a176069b
Autor:
Getachew Debas Belew, Joao Silva, Joao Rito, Ludgero Tavares, Ivan Viegas, Jose Teixeira, Paulo J. Oliveira, Maria Paula Macedo, John G. Jones
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 2050-2056 (2019)
Deuterated water (2H2O) is widely used for measuring de novo lipogenesis (DNL). 2H is incorporated into fatty acids via exchange between body water and the hydrogens of acetyl-CoA, malonyl-CoA, and NADPH. Previous studies concluded that these exchang
Externí odkaz:
https://doaj.org/article/a1eb5a82beb84feab5840a64f5899ac2
Autor:
Margarida Coelho, Rita S. Patarrão, Inês Sousa-Lima, Rogério T. Ribeiro, Maria João Meneses, Rita Andrade, Vera M. Mendes, Bruno Manadas, João Filipe Raposo, M. Paula Macedo, John G. Jones
Publikováno v:
Nutrients, Vol 15, Iss 1, p 4 (2022)
Coffee may protect against non-alcoholic fatty liver disease (NAFLD), but the roles of the caffeine and non-caffeine components are unclear. Coffee intake by 156 overweight subjects (87% with Type-2-Diabetes, T2D) was assessed via a questionnaire, wi
Externí odkaz:
https://doaj.org/article/56810c16aca34c769c95200f1e1f55bb
Autor:
Ivan Viegas, Giada Di Nunzio, Getachew D. Belew, Alejandra N. Torres, João G. Silva, Luis Perpétuo, Cristina Barosa, Ludgero C. Tavares, John G. Jones
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1142 (2022)
Dietary glucose and fructose are both efficiently assimilated by the liver but a comprehensive measurement of this process starting from their conversion to sugar phosphates, involvement of the pentose phosphate pathway (PPP), and conversion to glyco
Externí odkaz:
https://doaj.org/article/e0c02b55101e4cdf8eef3ff53a80df1a