Výsledky vyhledávání - "John G. Haggerty"

Growth and differentiation regulate CD44 expression on human keratinocytes

Autor: Leonard M. Milstone, Jing Zhou, John G. Haggerty

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 35:228-235

Several members of the CD44 family of hyaluronan receptors are expressed on keratinocytes. To identify factors that might be important in regulating CD44 expression, we studied CD44 expression on keratinocytes growing in vitro under a variety of cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e20877c8a398edb969f0016936b3f79
https://doi.org/10.1007/s11626-999-0031-7

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β-L-1,3-Dioxolane-Cytidine:A Novel Nucleoside ThatInhibits Proliferation andInduces Differentiation ofKeratinocytes in vitro

Autor: Y.-C. Cheng, John G. Haggerty, Pauline M. Schwartz

Publikováno v: Skin Pharmacology and Physiology. 11:207-213

β-L-1,3-Dioxolane-cytidine (L-(–)-OddC) is a novel L-nucleoside, and its antitumor activity is under investigation in clinical trials. To evaluate the potential of L-(–)-OddC for treating hyperproliferative diseases of the skin, we examined its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::115cd9360293679609f659bb81dc6b36
https://doi.org/10.1159/000029829

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CD44 Expression on Epidermal Melanocytes

Autor: Kyle W. Herbold, Leonard M. Milstone, John G. Haggerty, Jing Zhou

Publikováno v: Journal of Investigative Dermatology. 106:1230-1235

We examined CD44 expression on melanocytes to begin to understand what role CD44 might have in the normal behavior of melanocytes and to provide a basis for comparing CD44 expression in melanoma cells. CD44 was expressed on the entire surface of mela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d94ab72a9b2bcb4b4456bd714f1b15
https://doi.org/10.1111/1523-1747.ep12348871

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Epican, a heparan/chondroitin sulfate proteoglycan form of CD44, mediates cell-cell adhesion

Autor: L.C. Kugelman, John G. Haggerty, L. Hough-Monroe, Jeffrey R. Bender, Leonard M. Milstone

Publikováno v: Journal of Cell Science. 107:3183-3190

Epican is a heparan/chondroitin sulfate proteoglycan form of CD44 and is expressed on the surface of keratinocytes from the basal layer to the granular layer of the epidermis. To analyze the adhesive properties of epican apart from the influence of o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6252cb6ee88e518aeaa9906481ef9a
https://doi.org/10.1242/jcs.107.11.3183

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Response of stratified cultures of human keratinocytes to disruption of proteoglycan synthesis by p-nitrophenyl-beta-D-xylopyranoside

Autor: John G. Haggerty, Leonard M. Milstone, Randolph H. Bretton

Publikováno v: Journal of cellular physiology. 158(1)

Proteoglycans play a role in regulating proliferation and adhesion of cells to each other and to the basal lamina. Synthesis of proteoglycans is disrupted by beta-xylosides, which serve as alternate substrate sites for glycosaminoglycan chain attachm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a545db1b8ac2a9eec199fca30061949
https://pubmed.ncbi.nlm.nih.gov/8263027

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Identification and characterization of a cell surface proteoglycan on keratinocytes

Autor: Leonard M. Milstone, John G. Haggerty, Randolph H. Bretton

Publikováno v: The Journal of investigative dermatology. 99(4)

Proteoglycans fill the intercellular space between keratinocytes but their structure and function are not well understood. We have identified and partially characterized one intercellular proteoglycan on human keratinocytes, for which we propose the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a8e37ffb351557ed3edc4a7eeac8fb
https://pubmed.ncbi.nlm.nih.gov/1401993

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Increased Na(+)-H+ antiporter activity in apical membrane vesicles from mutant LLC-PK1 cells

Autor: Robert F. Reilly, Carolyn W. Slayman, Peter S. Aronson, Edward A. Adelberg, John G. Haggerty

Publikováno v: The American journal of physiology. 260(4 Pt 1)

In whole cell experiments, the PKE20 mutant of the renal epithelial cell line LLC-PK1 displays a severalfold elevation of Na(+)-H+ antiporter activity at the apical surface (J.G. Haggerty, N. Agarwal, R.F. Reilly, E. A. Adelberg, and C.W. Slayman. Pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8cbf38e7cbeffebbf3c9430f582084
https://pubmed.ncbi.nlm.nih.gov/1673319

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Epican, a heparan sulfate proteoglycan form of CD44 on keratinocytes, is a cell-cell adhesion molecule

Autor: Leonard M. Milstone, John G. Haggerty, Lisa C. Kugelman

Publikováno v: Journal of Dermatological Science. 6:62

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b10b6aa7c852b78761924b4e6fe3fa18
https://doi.org/10.1016/0923-1811(93)91071-2

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Inhibition of electron transfer in the cytochromeb-c 1 segment of the mitochondrial respiratory chain by a synthetic analogue of ubiquinone

Autor: John G. Haggerty, Bernard L. Trumpower

Publikováno v: Journal of Bioenergetics and Biomembranes. 12:151-164

A synthetic analogue of ubiquinone, 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole, inhibits oxidation of succinate and NADH-linked substrates by rat liver mitochondria. Inhibition occurs both in the presence (state 3) and absence (state 4) of ADP. Wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42c208b2e8012d8101c9292ae43b2059
https://doi.org/10.1007/bf00744680

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