Zobrazeno 1 - 10
of 80
pro vyhledávání: '"John G. Gambertoglio"'
Autor:
Francesca T. Aweeka, John G. Gambertoglio, Anne Hedman, Patricia Schoenfeld, Sarah Martin-Munley, Rodney Omachi, Mark A. Jacobson, Shirley M. Tsunoda
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 20:350-357
Background Foscarnet is an antiviral agent commonly used for managing patients with cytomegalovirus infection. Despite its clinical usefulness, foscarnet is associated with substantial adverse effects including nephrotoxicity. Moreover, foscarnet is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba94189ed7593ec1a3c900e834ae77e
https://doi.org/10.1097/00042560-199904010-00005
https://doi.org/10.1097/00042560-199904010-00005
Autor:
John G. Gambertoglio, Patricia Schoenfeld, Suzanne R. Brody, Kenneth C. Cundy, Michael H. Humphreys, Francesca T. Aweeka
Publikováno v:
Clinical Pharmacology & Therapeutics. 65:21-28
Background Cidofovir is an antiviral agent used for the treatment of cytomegalovirus infection in patients with acquired immunodeficiency syndrome. Because cidofovir is primarily eliminated by the kidneys and because its main adverse effect is nephro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8704f4419f692932fc3be37efe79446
https://doi.org/10.1038/clpt.1999.3
https://doi.org/10.1038/clpt.1999.3
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 21:2947-2956
The size of intracellular 2′-deoxythymidine-5′-triphosphate (dTTP) pools is an important indicator of cytotoxicity in cells exposed to antiviral drugs and mutagens. We describe an ion paired reverse-phase high performance liquid chromatographic (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f90c6d3b29bfd09a61a562a790302622
https://doi.org/10.1080/10826079808006878
https://doi.org/10.1080/10826079808006878
Autor:
John G. Gambertoglio, Katrin Peter
Publikováno v:
Pharmaceutical Research. 15:819-825
Dramatic reductions of viral load and increased survival have been achieved in patients infected with the Human Immunodeficiency Virus (HIV) with the introduction of combination antiretroviral therapy. Currently 11 agents including nucleoside reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14209ae6bada3ce84360cf64fb01030a
https://doi.org/10.1023/a:1011956011207
https://doi.org/10.1023/a:1011956011207
Autor:
John G. Gambertoglio, Mae Kwong, May Mak, David L. Cutler, James O. Kahn, Mel Affrime, Francesca T. Aweeka, Almira Al-Uzri
Publikováno v:
The Journal of Clinical Pharmacology. 36:1107-1113
Recombinant human granulocyte-macrophage colony-stimulating factor (rHu GM-CSF) enhances bone marrow production of and stimulates granulocytes, macrophages, and eosinophils. Granulocyte-macrophage colony-stimulating factor may be used concomitantly w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7e789e353c7376efef1bb1b9af919f
https://doi.org/10.1002/j.1552-4604.1996.tb04163.x
https://doi.org/10.1002/j.1552-4604.1996.tb04163.x
Autor:
John G. Gambertoglio, Thomayant Prueksaritanont, Stephen J. Tomlanovich, Marvin R. Garovoy, Suneel K. Gupta, Francesca T. Aweeka, Marianne Lantz, Claudia H. d'Uscio, Leslie Z. Benet
Publikováno v:
The Journal of Clinical Pharmacology. 35:967-973
The immunopharmacodynamics of cyclosporine were investigated in eight hemodialysis patients awaiting renal transplantation. Cyclosporine was administered orally (10 mg/kg) and intravenously (4 mg/kg), with both administrations separated by at least o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbab1993852bfcb08840099bb488892
https://doi.org/10.1002/j.1552-4604.1995.tb04012.x
https://doi.org/10.1002/j.1552-4604.1995.tb04012.x
Autor:
James O. Kahn, Francesca T. Aweeka, Katrin Peter, May Mak, Melton B. Affrime, Amira Al-Uzri, Carmen Dett, David L. Cutler, Roberto Guerciolini, John G. Gambertoglio, Jose Franco
Publikováno v:
The Journal of Clinical Pharmacology. 35:856-864
Combination therapy with zidovudine and recombinant human granulocyte-macrophage colony stimulating factor (rHu GM-CSF) may be warranted, owing to the bone marrow suppressive effects of zidovudine. A study of 16 patients, 8 of whom had acquired immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6838ba638f0417b0b4c5cda078ca342f
https://doi.org/10.1002/j.1552-4604.1995.tb04130.x
https://doi.org/10.1002/j.1552-4604.1995.tb04130.x
Autor:
Patricia Lizak, Anura L. Jayewardene, Françoise Kramer, Charles van der Horst, John G. Gambertoglio, Bruce Polsky, Francesca T. Aweeka, William Tong, Lisa Emrick, Mark A. Jacobson
Publikováno v:
Clinical Pharmacology & Therapeutics. 57:403-412
Introduction The use of foscarnet and ganciclovir as a combination treatment for cytomegalovirus retinitis is increasing because of limitations associated with single agent therapy. Methods The pharmacokinetics of foscarnet and ganciclovir were deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cefaf3a096839c15233d1846f47eef
https://doi.org/10.1016/0009-9236(95)90209-0
https://doi.org/10.1016/0009-9236(95)90209-0
Autor:
John G. Gambertoglio, John F. Flaherty, Y. W. Francis Lam, Patricia Y. Schoenfeld, Lucy Yumena
Publikováno v:
Journal of Antimicrobial Chemotherapy. 36:157-163
Roxithromycin is a macrolide antibiotic with a spectrum of activity similar to erythromycin. Roxithromycin has been shown to have a favourable pharmacokinetic profile with more reliable absorption and higher, prolonged plasma and tissue concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5dbf9d985628bf289d061e5c0615117
https://doi.org/10.1093/jac/36.1.157
https://doi.org/10.1093/jac/36.1.157
Publikováno v:
Journal of Liquid Chromatography. 17:4157-4167
An ion paired reversed - phase high performance liquid chromatographic assay for ceftizoxime in human abscess fluid using barbital as the internal standard is described. Sample preparation consists of precipitating the proteins in diluted abscess flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca313aa7f6bbdbb170c631c90021ffa0
https://doi.org/10.1080/10826079408013608
https://doi.org/10.1080/10826079408013608