Zobrazeno 1 - 10
of 62
pro vyhledávání: '"John G. Elliot"'
Autor:
Carolyn J. Wang, Peter B. Noble, John G. Elliot, Yu Suk Choi, Alan L. James, Kimberley C. W. Wang
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L179-L189
Patients with comorbid asthma-obesity experience greater disease severity and are less responsive to therapy. We have previously reported adipose tissue within the airway wall that positively correlated with body mass index. Accumulation of biologica
Publikováno v:
Comprehensive Physiology. :4321-4353
Publikováno v:
Respirology. 28:223-225
Autor:
Kimberley C. W. Wang, Graham M. Donovan, Sejal Saglani, Thais Mauad, Alan L. James, John G. Elliot, Peter B. Noble
Publikováno v:
Respirology. 27:493-500
The airway smooth muscle (ASM) layer thickens during development. Identifying the mechanism(s) for normal structural maturation of the ASM reveals pathways susceptible to disease processes. This study characterized thickening of the ASM layer from fo
Autor:
Alan L. James, Graham M. Donovan, Francis H. Y. Green, Thais Mauad, Michael J. Abramson, Alvenia Cairncross, Peter B. Noble, John G. Elliot
Publikováno v:
American journal of respiratory and critical care medicine.
Ventilatory defects in asthma are heterogeneous and may represent the distribution of airway smooth muscle (ASM) remodelling.To determine the distribution of ASM remodelling in mild-severe asthma.The ASM area was measured in 9 airway levels in 3 bron
Autor:
James T. H. Wong, John G. Elliot, Kimberley C. W. Wang, Alan L. James, Peter J. Henry, Shane K. Maloney, Peter B. Noble
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 67:125-127
Autor:
Sonia R Rosner, Christopher D Pascoe, Elizabeth Blankman, Christopher C Jensen, Ramaswamy Krishnan, Alan L James, John G Elliot, Francis H Green, Jeffrey C Liu, Chun Y Seow, Jin-Ah Park, Mary C Beckerle, Peter D Paré, Jeffrey J Fredberg, Mark A Smith
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0171728 (2017)
Bronchospasm induced in non-asthmatic human subjects can be easily reversed by a deep inspiration (DI) whereas bronchospasm that occurs spontaneously in asthmatic subjects cannot. This physiological effect of a DI has been attributed to the manner in
Externí odkaz:
https://doaj.org/article/1629d355381e4d5cb818f4e71db3807d
Autor:
David H. Broide, Alan L. James, Peter Rosenthal, Gyu Young Hur, Francis H. Y. Green, John G. Elliot, Ning Weng, Marina Miller, Alex Pham
Publikováno v:
Clin Exp Allergy
Autor:
John G. Elliot, Alvenia Cairncross, Peter B. Noble, Alan L. James, Robyn L. Jones, Peter K. McFawn
Publikováno v:
Journal of Applied Physiology. 128:757-767
The volume fraction of extracellular matrix (ECM) within the layer of airway smooth muscle (ASM) is increased in subjects with fixed airflow obstruction. We postulated that changes in ECM within the ASM layer will impact force transmission during ind
Autor:
Michael J. Hackmann, John G. Elliot, Francis H.Y. Green, Alvenia Cairncross, Barry Cense, Robert A. McLaughlin, David Langton, Alan L. James, Peter B. Noble, Graham M. Donovan
Publikováno v:
Respiratory physiologyneurobiology. 301
Clinical visualization and quantification of the amount and distribution of airway smooth muscle (ASM) in the lungs of individuals with asthma has major implications for our understanding of airway wall remodeling as well as treatments targeted at th