Zobrazeno 1 - 5
of 5
pro vyhledávání: '"John G M, Mina"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Toxoplasma gondii is a widespread single-celled intracellular eukaryotic apicomplexan protozoan parasite primarily associated with mammalian foetal impairment and miscarriage, including in humans. Is estimated that approximately one third of the huma
Externí odkaz:
https://doaj.org/article/f405bf882426419988be7e8628e4e0d8
Autor:
Shashank Dadsena, Svenja Bockelmann, John G. M. Mina, Dina G. Hassan, Sergei Korneev, Guilherme Razzera, Helene Jahn, Patrick Niekamp, Dagmar Müller, Markus Schneider, Fikadu G. Tafesse, Siewert J. Marrink, Manuel N. Melo, Joost C. M. Holthuis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Ceramides are lipids that act directly on mitochondria to trigger apoptosis, but the underlying mechanism remains largely unclear. Here authors use a photoactivatable ceramide probe combined with a computation approach and functional studies to ident
Externí odkaz:
https://doaj.org/article/161032635f8246f6afb463a1fd58d74b
Autor:
Hany M. Elsheikha, Alaa T. Al-Sandaqchi, Mohammad S. R. Harun, Francesca Winterton, Ali Altharawi, Nashwa A. Elsaied, Carl W. Stevenson, William MacNaughtan, John G. M. Mina, Paul W. Denny, Gianfelice Cinque, Ka Lung Andrew Chan
Publikováno v:
Cells, Vol 11, Iss 5, p 811 (2022)
Toxoplasma gondii (T. gondii) is an opportunistic protozoan that can cause brain infection and other serious health consequences in immuno-compromised individuals. This parasite has a remarkable ability to cross biological barriers and exploit the ho
Externí odkaz:
https://doaj.org/article/4f657002c9be4452a1f97321f5de9c4c
Autor:
Hany M. Elsheikha, Alaa T. Al-Sandaqchi, Mohammad S. R. Harun, Francesca Winterton, Ali Altharawi, Nashwa A. Elsaied, Carl W. Stevenson, William MacNaughtan, John G. M. Mina, Paul W. Denny, Gianfelice Cinque, Ka Lung Andrew Chan
Publikováno v:
Cells, 2022, Vol.11(5), pp.811 [Peer Reviewed Journal]
Cells; Volume 11; Issue 5; Pages: 811
Cells; Volume 11; Issue 5; Pages: 811
Toxoplasma gondii (T. gondii) is an opportunistic protozoan that can cause brain infection and other serious health consequences in immuno-compromised individuals. This parasite has a remarkable ability to cross biological barriers and exploit the ho
Autor:
John G M, Mina, Rebecca L, Charlton, Edubiel, Alpizar-Sosa, Douglas O, Escrivani, Christopher, Brown, Amjed, Alqaisi, Maria Paula G, Borsodi, Claudia P, Figueiredo, Emanuelle V, de Lima, Emily A, Dickie, Wenbin, Wei, Robson, Coutinho-Silva, Andy, Merritt, Terry K, Smith, Michael P, Barrett, Bartira, Rossi-Bergmann, Paul W, Denny, Patrick G, Steel
Publikováno v:
ACS Infectious Diseases
Current chemotherapeutics for leishmaniasis have multiple deficiencies, and there is a need for new safe, efficacious, and affordable medicines. This study describes a successful drug repurposing approach that identifies the over-the-counter antihist