Zobrazeno 1 - 10
of 719
pro vyhledávání: '"John G Gribben"'
Autor:
Christopher P. Fox, William Townsend, John G. Gribben, Tobias Menne, Nagesh Kalakonda, Paula Williams, Farah Toron, Emma Tyas, Miranda Cooper, Joshua Rickards, John Radford
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 992-997 (2024)
Abstract Autologous stem‐cell transplantation (ASCT) is standard therapy for relapsed/refractory large B‐cell lymphoma (R/R LBCL), but many patients are either ineligible or unable to receive it. This retrospective study characterized outcomes in
Externí odkaz:
https://doaj.org/article/9d95dec08e514e938f8b71fce268e73c
Autor:
Weronika E. Borek, Luis Nobre, S. Federico Pedicona, Amy E. Campbell, Josie A. Christopher, Nazrath Nawaz, David N. Perkins, Pedro Moreno-Cardoso, Janet Kelsall, Harriet R. Ferguson, Bela Patel, Paolo Gallipoli, Andrea Arruda, Alex J. Ambinder, Andrew Thompson, Andrew Williamson, Gabriel Ghiaur, Mark D. Minden, John G. Gribben, David J. Britton, Pedro R. Cutillas, Arran D. Dokal
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105316- (2024)
Summary: Background: Acute myeloid leukaemia (AML) is a bone marrow malignancy with poor prognosis. One of several treatments for AML is midostaurin combined with intensive chemotherapy (MIC), currently approved for FLT3 mutation-positive (FLT3-MP) A
Externí odkaz:
https://doaj.org/article/c1ed1c39383540cb899802e9a5af0c25
Autor:
Emanuela Carlotti, David Wrench, Guglielmo Rosignoli, Jacek Marzec, Ajanthah Sangaralingam, Lena Hazanov, Miri Michaeli, Simon Hallam, Tracy Chaplin, Sameena Iqbal, Maria Calaminici, Bryan Young, Ramit Mehr, Peter Campbell, Jude Fitzgibbon, John G Gribben
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0134833 (2015)
Understanding the dynamics of evolution of Follicular Lymphoma (FL) clones during disease progression is important for monitoring and targeting this tumor effectively. Genetic profiling of serial FL biopsies and examples of FL transmission following
Externí odkaz:
https://doaj.org/article/69bd4bb7c9f7459aa46cb9de4b5b04a4
Autor:
William K Decker, Nina Shah, Dongxia Xing, Ruth Lapushin, Sufang Li, Simon N Robinson, Hong Yang, Simrit Parmar, Matthew M Halpert, Michael J Keating, John G Gribben, Jeffrey J Molldrem, Elizabeth J Shpall, William G Wierda
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51390 (2012)
Though remissions have been observed following allo-HSCT for the treatment of CLL, many CLL patients are ineligible for transplant due to the lack of HLA-compatible donors. The use of umbilical cord blood (UCB) permits transplantation of many patient
Externí odkaz:
https://doaj.org/article/755950a4c5214302be9eb8cac96b0847
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32584 (2012)
Here we show that bortezomib induces effective proteasome inhibition and accumulation of poly-ubiquitinated proteins in diffuse large B-cell lymphoma (DLBCL) cells. This leads to induction of endoplasmic reticulum (ER) stress as demonstrated by accum
Externí odkaz:
https://doaj.org/article/6b8ad8319bb347f3843f313eb01c2028
Autor:
Arran Dokal, Weronika E. Borek, Luis Nobre, Salvatore Federico Pedicona, Bela Wrench, Paolo Gallipoli, Andrea Arruda, Amy E. Campbell, Nazrath Nawaz, Harriet R. Ferguson, David N. Perkins, Pedro Moreno-Cardoso, Andrew Thompson, Andrew J.K. Williamson, Mark D. Minden, John G. Gribben, David J. Britton, Pedro R. Cutillas
Publikováno v:
HemaSphere, Vol 7, p e3920765 (2023)
Externí odkaz:
https://doaj.org/article/9587d3fdbfdb464ab33fdd2f65eb362d
Autor:
William Townsend, Wolfgang Hiddemann, Christian Buske, Guillaume Cartron, David Cunningham, Martin J.S. Dyer, John G. Gribben, Elizabeth H. Phillips, Martin Dreyling, John F. Seymour, Andrew Grigg, Judith Trotman, Tong-Yu Lin, Xiao-Nan Hong, Dirk Kingbiel, Tina G. Nielsen, Andrea Knapp, Michael Herold, Robert Marcus
Publikováno v:
HemaSphere, Vol 7, Iss 7, p e919 (2023)
The phase III GALLIUM trial assessed the safety and efficacy of obinutuzumab-based versus rituximab-based immunochemotherapy in patients with previously untreated follicular lymphoma (FL) or marginal zone lymphoma (MZL). At the primary analysis, the
Externí odkaz:
https://doaj.org/article/54ee041689654f5486a8b741a193c36c
Autor:
Kai Rejeski, Raffaella Greco, Francesco Onida, Isabel Sánchez-Ortega, Chiara Bonini, Anna Sureda, John G. Gribben, Ibrahim Yakoub-Agha, Marion Subklewe
Publikováno v:
HemaSphere, Vol 7, Iss 5, p e889 (2023)
Hematological toxicity represents the most common grade ≥3 toxicity after chimeric antigen receptor (CAR) T-cell therapy. However, its underlying pathophysiology is incompletely understood and its grading and management remains ill-defined. To info
Externí odkaz:
https://doaj.org/article/227c6b423e7b4927bf4310bcb2ec78ef
Autor:
Tarec Christoffer El-Galaly, Verena I. Gaidzik, Mihnea-Alexandru Gaman, Darko Antic, Jessica Okosun, Mhairi Copland, Veronika Sexl, Adele K. Fielding, Robin Doeswijk, Helen Parker, Martin Dreyling, Konstanze Döhner, António Medina Almeida, Elizabeth Macintyre, John G. Gribben, Kirsten Grønbæk, on behalf of the EHA Diversity, Equity, and Inclusion Taskforce
Publikováno v:
HemaSphere, Vol 7, Iss 3, p e842 (2023)
Externí odkaz:
https://doaj.org/article/061eec178a40471bb4aebc1c6c453233
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Follicular lymphoma (FL) is an indolent disease, characterized by a median life expectancy of 18-20 years and by intermittent periods of relapse and remission. FL frequently transforms into the more aggressive diffuse large B cell lymphoma (t-FL). In
Externí odkaz:
https://doaj.org/article/52ee7aea56d745dca2cd50e74bcfe318