Zobrazeno 1 - 10
of 94
pro vyhledávání: '"John G, Vandenbergh"'
Autor:
Barry S. McIntyre, Susan Woskie, Teresa M. Schnorr, Jane Adams, L. Earl Gray, John G. Vandenbergh, Sherry G. Selevan, Robert E. Chapin, Simon W. Hayward, Kim Boekelheide, Peter S.J. Lees, Kenneth M. Portier
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 83:157-395
Robert E. Chapin, Jane Adams, Kim Boekelheide, L. Earl Gray Jr, Simon W. Hayward, Peter S.J. Lees, Barry S. McIntyre, Kenneth M. Portier, Teresa M. Schnorr, Sherry G. Selevan, John G. Vandenbergh, and Susan R. Woskie Pfizer, Inc., Groton, CT Universi
Autor:
Linda S. Birnbaum, Catherine A. Richter, John G. Vandenbergh, Retha R. Newbold, Beverly S. Rubin, Francesca Farabollini, Debby Walser-Kuntz, Frederick S. vom Saal, Chris E. Talsness
Publikováno v:
Reproductive Toxicology. 24:199-224
Concern is mounting regarding the human health and environmental effects of bisphenol A (BPA), a high-production-volume chemical used in synthesis of plastics. We have reviewed the growing literature on effects of low doses of BPA, below 50 mg/kg/day
Autor:
Leon Earl Gray, Joseph S. Ostby, Christy S. Lambright, Andrew K. Hotchkiss, Louise Parks-Saldutti, John G. Vandenbergh
Publikováno v:
Toxicological Sciences. 96:335-345
In mammals, abnormal increases in fetal androgens disrupt normal development of the female phenotype. Due to the recent concern regarding environmental androgen-active chemicals, there is a need to identify sources of fetal androgen variation and sen
Publikováno v:
Neurotoxicology and Teratology. 28:103-110
Endocrine-disrupting chemicals (EDCs) are synthetic chemicals that arise from sources such as pesticides and have the ability to mimic or inhibit gonadal steroid hormones. The objective of this research was to examine the effects of EDCs on the behav
Autor:
Christy S. Lambright, Johnathan Furr, L.G. Parks-Saldutti, Joseph S. Ostby, Leon Earl Gray, John G. Vandenbergh, Andrew K. Hotchkiss
Publikováno v:
Biology of Reproduction. 71:1852-1861
Prenatal exposure to environmental chemicals that interfere with the androgen signaling pathway can cause permanent adverse effects on reproductive development in male rats. The objectives of this study were to 1) determine whether a documented antia
Publikováno v:
Physiology & Behavior. 79:151-156
During mammalian sexual differentiation, the androgens, testosterone and dihydrotestosterone are critical for the organization of the male phenotype. In rats, play behavior is sexually dimorphic. Administration of exogenous androgens during the perin
Autor:
John G. Vandenbergh, Zhongxing Liang, Marina E. Eremeeva, Christopher D. Paddock, Sherif R. Zaki, David Silverman, Gregory A. Dasch
Publikováno v:
Annals of the New York Academy of Sciences. 990:468-473
The pine vole, Microtus pinetorum, was evaluated as a laboratory animal model for infection with Rickettsia rickettsii. Voles demonstrated signs of acute disease, and 45% of infected animals died following intraperitoneal infection with 3 × 106 plaq
Autor:
Bryce C. Ryan, John G. Vandenbergh
Publikováno v:
Neuroscience & Biobehavioral Reviews. 26:665-678
A review of the literature suggests that individual variability in sex-related traits may be influenced by variations in hormonal exposure during fetal development. In litter-bearing mammals, fetuses develop in utero and may be subjected to differing
Autor:
Richard F. Lyman, Robert R. H. Anholt, Alice H Luo, John G. Vandenbergh, Kennedy S. Wekesa, Eliot H Cannon
Publikováno v:
Brain Research. 941:62-71
The ability to respond to chemical signals is essential for the survival and reproduction of most organisms. Olfactory signaling involves odorant receptor-mediated activation of G(olf), a homologue of G(s), on the dendrites of olfactory neurons. Olfa
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 278:R320-R330
Five allelic mutants of the diabetes (db) gene have been previously described in mice and rats causing obesity, infertility, and varying degrees of diabetes. We have identified a new, spontaneous mutation resulting in obesity and diabetes in a colony