Zobrazeno 1 - 10
of 106
pro vyhledávání: '"John F.X Diffley"'
Autor:
Berta Canal, Allison W. McClure, Joseph F. Curran, Mary Wu, Rachel Ulferts, Florian Weissmann, Jingkun Zeng, Agustina P. Bertolin, Jennifer C. Milligan, Souradeep Basu, Lucy S. Drury, Tom Deegan, Ryo Fujisawa, Emma L. Roberts, Clovis Basier, Karim Labib, Rupert Beale, Michael Howell, John F.X Diffley
Publikováno v:
Biochemical Journal
SummarySARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs. Healthcare systems worldwide are under great pressure, and there is urgent need for effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fecacd84c888a43831e441cefbc679e
http://europepmc.org/articles/PMC8286829
http://europepmc.org/articles/PMC8286829
Autor:
Kang Wei Tan, Emma L. Roberts, Tiffany Mak, Lucy S. Drury, Souradeep Basu, Berta Canal, Michael Howell, Joseph F. Curran, Florian Weissmann, Karim Labib, Tom D Deegan, John F.X. Diffley, Allison W McClure, Ryo Fujisawa, Mary Wu, Victoria H. Cowling, Rachel Ulferts, Clovis Basier, Rupert Beale, Theresa U. Zeisner, Chew Theng Lim
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause a fatal disease in humans. There is currently only one antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74acc162b19fe84f371a9c793c9d9297
http://europepmc.org/articles/PMC8286817
http://europepmc.org/articles/PMC8286817
Autor:
Chew Theng Lim, Kang Wei Tan, Mary Wu, Rachel Ulferts, Lee A. Armstrong, Eiko Ozono, Lucy S. Drury, Jennifer C. Milligan, Theresa U. Zeisner, Jingkun Zeng, Florian Weissmann, Berta Canal, Ganka Bineva-Todd, Michael Howell, Nicola O'Reilly, Rupert Beale, Yogesh Kulathu, Karim Labib, John F.X. Diffley
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has emerged as the biggest life-threatening disease of this century. Whilst vaccination should provide a long-term solution, this is pitted against the constant threat of mutations in the virus rendering the current vaccines les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc295ebc783870d82ca11f9dd713752
http://europepmc.org/articles/PMC8286840
http://europepmc.org/articles/PMC8286840
Autor:
Nicola O’Reilly, John F.X. Diffley, Dhira Joshi, George Papageorgiou, Theresa U. Zeisner, Jennifer C. Milligan
Publikováno v:
Rsc Advances
An improved and expedient technique for the synthesis of peptidyl-fluoromethyl ketones is described. The methodology is based on prior coupling of an aspartate fluoromethyl ketone to a linker and mounting it onto resin-bound methylbenzhydrylamine hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfff6ec0524f9473fc34272729bff79
http://europepmc.org/articles/PMC8185805
http://europepmc.org/articles/PMC8185805
Autor:
John F.X. Diffley, Max E. Douglas
Publikováno v:
Nucleic Acids Research
Telomeres are copied and reassembled each cell division cycle through a multistep process called telomere replication. Most telomeric DNA is duplicated semiconservatively during this process, but replication forks frequently pause or stall at telomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c0e15c9b2eece1efafa66aa368ec7d
http://europepmc.org/articles/PMC8191780
http://europepmc.org/articles/PMC8191780
Publikováno v:
Cell. 186:528-542.e14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ae6fb35612267cb1259bd8a3e92d4c
https://doi.org/10.1016/j.cell.2022.12.036
https://doi.org/10.1016/j.cell.2022.12.036
Autor:
John F.X. Diffley, Erik Johansson
Publikováno v:
Current Biology
Summary Single-stranded DNA breaks, or nicks, are amongst the most common forms of DNA damage in cells. They can be repaired by ligation; however, if a nick occurs just ahead of an approaching replisome, the outcome is a collapsed replication fork co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886cc08e2fa8653bb4bb2c4547092cac
https://pubmed.ncbi.nlm.nih.gov/34102115
https://pubmed.ncbi.nlm.nih.gov/34102115
Autor:
Florian Weissmann, Berta Canal, Rachel Ulferts, Mary Wu, Michael Howell, John F.X. Diffley, Lucy S. Drury, Jennifer C. Milligan, Rupert Beale, Jingkun Zeng, Agustina P Bertolin, Viktor Posse
Publikováno v:
Biochemical Journal
SummaryThe coronavirus disease 2019 (COVID-19) global pandemic has turned into the largest public health and economic crisis in recent history impacting virtually all sectors of society. There is a need for effective therapeutics to battle the ongoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e349d752e1f3eb65b7e78de708e1dc8d
https://doi.org/10.1101/2021.04.07.438807
https://doi.org/10.1101/2021.04.07.438807
Autor:
Mary Wu, Clovis Basier, George Papageorgiou, Michael Howell, Christelle Soudy, Theresa U. Zeisner, Rachel Ulferts, John F.X. Diffley, Chew Theng Lim, Dhira Joshi, Joseph F. Curran, Florian Weissmann, Hema Nagaraj, Tom D Deegan, Ryo Fujisawa, Berta Canal, Karim Labib, Kang Wei Tan, Ganka Bineva-Todd, Jennifer C. Milligan, Rupert Beale
The coronavirus 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread around the world with unprecedented health and socio-economic effects for the global population. While different vaccines are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9335764f2cf6ed64e157d65e251c782
https://doi.org/10.1101/2021.04.07.438804
https://doi.org/10.1101/2021.04.07.438804