Zobrazeno 1 - 10
of 25
pro vyhledávání: '"John F. Wyman"'
Autor:
Paul D. Boggs, David A. Engelhart, Eric S. Lavins, Kimberly D. Snell, Frank P. Miller, Shaena M. Taylor, Rindi N. Norris, Erica J. Armstrong, John F. Wyman
Publikováno v:
Journal of Analytical Toxicology. 37:182-185
3,4-Methylenedioxypyrovalerone (MDPV) is a psychoactive, synthetic analog of the central nervous system stimulant cathinone. Its recent popularity as a recreational drug in the United States has led to numerous reports to poison control centers acros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca64ce30044b29a6589e1e388677496
https://doi.org/10.1093/jat/bkt001
https://doi.org/10.1093/jat/bkt001
Publikováno v:
Journal of Forensic Sciences. 57:544-549
Skeletal remains of a domestic pig were assessed for relative distribution of amitriptyline, citalopram, and metabolites. Following acute exposure and outdoor decomposition for 2 years, drugs and metabolites were analyzed in 13 different bones. Bones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3008ae5ac05db2f6357ee3957816fd3c
https://doi.org/10.1111/j.1556-4029.2011.01994.x
https://doi.org/10.1111/j.1556-4029.2011.01994.x
Autor:
Robert Shott, Bradley J. Lewis, John F. Wyman, Amber Simmons, Michael G Bissell, Nancy Kelly, Joseph Ohr, Richard John Howard, David Brobst, Dorothy E. Dean, Fernando Silveira, Rachel Yinger
Publikováno v:
Journal of Forensic Sciences. 56:694-699
Drug levels in decomposed individuals are difficult to interpret. Concentrations of 16 drugs were monitored in tissues (blood, brain, liver, kidney, muscle, and soil) from decomposing pigs for 1 week. Pigs were divided into groups (n = 5) with each g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::285ea0ddbd1ea8e85fb1bf2a6d655567
https://doi.org/10.1111/j.1556-4029.2011.01725.x
https://doi.org/10.1111/j.1556-4029.2011.01725.x
Autor:
John F. Wyman, Lou Ann Miller, Gerry Henningsen, Mark Wickstrom, Val R. Beasley, Wanda M. Haschek
Publikováno v:
Natural Toxins. 4:195-205
The cyanobacterial hepatotoxin, microcystin-LR (MCLR), is a potent protein phosphatase inhibitor that disrupts actin microfilament, cytokeratin intermediate filament, and microtubule networks in hepatocytes. To determine ultrastructural and biochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e093bdd5bebc5190ce3ce20f0d47b0ea
https://doi.org/10.1002/(sici)(1996)4:5<195::aid-nt1>3.0.co
https://doi.org/10.1002/(sici)(1996)4:5<195::aid-nt1>3.0.co
Publikováno v:
Electrophoresis. 18:642-646
Advances in tissue slice technology and a recent novel application of this technique to reproductive toxicology using bovine testis have demonstrated the remarkable utility of this approach. The objective of the present study was to combine this in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb6a2e4d65abf380b386bd4c64b7ca0
https://doi.org/10.1002/elps.1150180350
https://doi.org/10.1002/elps.1150180350
Autor:
John T. Cody, John F. Wyman
Publikováno v:
Journal of Analytical Toxicology. 29:759-761
Methamphetamine was detected in a 77-year-old male who had a history of congestive heart failure. Using a modification of a previously reported method, trifluoroacetyl-l-prolyl chloride was used to derivatize sympathomimetic amines to allow separatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4cc30100c29b8f4a7634164c0e29ab
https://doi.org/10.1093/jat/29.7.759
https://doi.org/10.1093/jat/29.7.759
Autor:
Cassandra E Cushman, Thomas P. Gilson, C. Randall Clark, Leon R. Glass, Krista L. Pekarski, Claire K. Naso-Kaspar, John F. Wyman, Eric S. Lavins
Publikováno v:
Journal of analytical toxicology. 37(8)
Forensic toxicologists consider detection of 6-acetylmorphine (6-AM) definitive evidence of heroin abuse. This study investigated the possibility that aspirin, when in solution with morphine, may acetylate morphine to produce acetylmorphine (AM). Mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf79482f840ca427b009f5e94f4b319
https://pubmed.ncbi.nlm.nih.gov/23956377
https://pubmed.ncbi.nlm.nih.gov/23956377
Autor:
Grant W Herndon, Claire K. Naso-Kaspar, John F. Wyman, Thomas P. Gilson, Joseph A Felo, Eric S. Lavins
Publikováno v:
Journal of analytical toxicology. 37(8)
'Lingering death' cases occur when the circumstances of death indicate an opiate overdose, but measured opiate blood levels are only in the therapeutic range; death results from cardiac and respiratory depression. This study examined the relative con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8aa64b5d59ca1e9d6220d2c86b9513
https://pubmed.ncbi.nlm.nih.gov/23869071
https://pubmed.ncbi.nlm.nih.gov/23869071
Autor:
Safdar All Khan, Mark Wickstrom, Val R. Beasley, Wanda M. Haschek, David J. Schaeffer, John F. Wyman, John E. Eriksson
Publikováno v:
Toxicologic Pathology. 23:326-337
Microcystin-LR (MCLR) is a cyanobacterial hepatotoxin that inhibits intracellular serine/threonine protein phosphatases causing disruption of actin microfilaments (MFs) and intermediate filaments (IFs) in hepatocytes. This study compared the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5686d97079671e926e27b09d664eda93
https://doi.org/10.1177/019262339502300309
https://doi.org/10.1177/019262339502300309
Publikováno v:
Chemical Research in Toxicology. 8:77-81
The perfluorinated carboxylic acid, perfluoro-n-decanoic acid (PFDA), is a known peroxisome proliferator which displays toxicity in rodents. Using a paired-tracer first-pass extraction technique, the effect of PFDA on hepatic glucose transport was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace6da1419c3ef8cdd83b1004e8b7876
https://doi.org/10.1021/tx00043a010
https://doi.org/10.1021/tx00043a010