Zobrazeno 1 - 10
of 20
pro vyhledávání: '"John F. Wheldrake"'
Publikováno v:
Journal of Biological Chemistry. 274:27076-27082
The mammalian cation-independent mannose 6-phosphate receptor (CI-MPR) binds mannose 6-phosphate-bearing glycoproteins and insulin-like growth factor (IGF)-II. However, the CI-MPR from the opossum has been reported to bind bovine IGF-II with low affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537aac3be93c10c1374fb2869c9f6264
https://doi.org/10.1074/jbc.274.38.27076
https://doi.org/10.1074/jbc.274.38.27076
Publikováno v:
Journal of Endocrinology. 161:445-453
Kangaroo IGF-II has been purified from western grey kangaroo (Macropus fuliginosus) serum and characterised in a number of in vitro assays. In addition, the complete cDNA sequence of mature IGF-II has been obtained by reverse-transcription polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911163503d34611a371a591e6718e46e
https://doi.org/10.1677/joe.0.1610445
https://doi.org/10.1677/joe.0.1610445
Publikováno v:
Journal of Endocrinology. 156:195-204
Insulin-like growth factor-I (IGF-I) and IGF-II have been purified to homogeneity from kangaroo (Macropus fuliginosus) serum, thus this represents the first report of the purification, sequencing and characterisation of marsupial IGFs. N-Terminal pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3749025868e94b76a110a3ef81b2f0ee
https://doi.org/10.1677/joe.0.1560195
https://doi.org/10.1677/joe.0.1560195
Autor:
John F. Wheldrake, Andrew J. Dunbar
Publikováno v:
Development, Growth and Differentiation. 39:617-624
The enzyme glutamine synthetase (GS) of Dictyostelium discoideum is developmentally regulated, preferentially localized in prespore cells and is likely to play an important role in controlling the levels of ammonia, a known morphogen, in this organis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1b8412d45c0287892133c5c4a64cd6
https://doi.org/10.1046/j.1440-169x.1997.t01-4-00009.x
https://doi.org/10.1046/j.1440-169x.1997.t01-4-00009.x
Autor:
John F. Wheldrake, Andrew J. Dunbar
Publikováno v:
Biochemistry and Cell Biology. 75:217-227
Glutamine synthetase (GS) from the cellular slime mould Dictyostelium discoideum was purified to apparent electrophoretic homogeneity with a final yield of 21.7%. The native enzyme appeared to be a GS-II type enzyme. SDS-PAGE of the final preparation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010605da7ef9aac5eb178fee2027cc47
https://doi.org/10.1139/o97-040
https://doi.org/10.1139/o97-040
Autor:
John F. Wheldrake, Andrew J. Dunbar
Publikováno v:
Microbiology. 141:1125-1130
SUMMARYThe enzyme glutamine synthetase (GS) is described for the first time inDictyostelium discoideum.The appearance of this enzyme is developmentally regulated. The level of activity is low in vegetative cells and increases more than threefold duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398c1335f141b368344ed9c874f05727
https://doi.org/10.1099/13500872-141-5-1125
https://doi.org/10.1099/13500872-141-5-1125
Publikováno v:
Biochimica et biophysica acta. 1576(1-2)
Betacellulin (BTC) belongs to the epidermal growth factor (EGF) family of peptide ligands that are characterized by a six-cysteine consensus motif (EGF-motif) that forms three intra-molecular disulfide bonds, crucial for binding the ErbB receptor fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ba542bac9bd1eeb687de8ed0810970
https://pubmed.ncbi.nlm.nih.gov/12031500
https://pubmed.ncbi.nlm.nih.gov/12031500
Publikováno v:
Microbiology (Reading, England). 145
The sori of Dictyostelium discoideum (strains SG1, SG2, NC4 and V12) contained more than 100 mM ammonium phosphate. Glutamine synthetase (GS), which could remove ammonia from the sorus, was not present in 2-d-old dormant spores but enzyme activity re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce2faabb293dee05249071faa3676c3
https://pubmed.ncbi.nlm.nih.gov/10463155
https://pubmed.ncbi.nlm.nih.gov/10463155
Autor:
John F. Wheldrake, Andrew J. Dunbar
Publikováno v:
FEMS microbiology letters. 115(1)
A protein kinase from Dictyostelium discoideum which phosphorylates the synthetic peptide, calmodulin-dependent protein kinase substrate (CDPKS, amino acid sequence: PLRRTLSVAA) and is stimulated by Ca2+/calmodulin is described. This is the first rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e451f029960f0723dd782b283a6b6a
https://pubmed.ncbi.nlm.nih.gov/8125240
https://pubmed.ncbi.nlm.nih.gov/8125240
Autor:
S. Schmidt, John F. Wheldrake
Publikováno v:
Molecular and cellular biochemistry. 126(2)
Incubation of Dictyostelium discoideum cells with selenate is known to inhibit vegetative growth. In this paper we show that in the presence of selenate macromolecules accumulate which can be converted to sulphated products once the selenate is remov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f692598441e4ae057415de88f56adb4
https://pubmed.ncbi.nlm.nih.gov/8302288
https://pubmed.ncbi.nlm.nih.gov/8302288