Zobrazeno 1 - 10
of 65
pro vyhledávání: '"John F. Thomson"'
Autor:
John F. Thomson
Publikováno v:
Annals of the New York Academy of Sciences. 84:736-744
Autor:
Sandra L. Tollaksen, Elizabeth A. Cerny, Sharron L. Nance, Y.E. Rahman, B.J. Wright, John F. Thomson
Publikováno v:
Experimental Biology and Medicine. 146:1173-1176
SummaryActinomycin D, when encapsulated within liposomes, is less toxic to mice than the nonencapsulated form. A single dose (0.75 mg/kg) or multiple doses (1 × 0.50, 4 × 0.25 mg/kg) significantly increased the mean survival time of mice inoculated
Publikováno v:
Archives of Biochemistry and Biophysics. 160:130-134
The use of density gradients constructed with mixtures of H 2 O and D 2 O for sedimentation studies of mouse liver mitochondria is described. A major advantage of the technique is the avoidance of a solute gradient and the possibility of membrane dam
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 146:484-492
Results obtained by zonal gradient centrifugations demonstrated that rat liver lysosomes are heterogeneous in terms of their enzyme contents. It is suggested that acid phosphatase and cathepsin C on one hand, and acid ribonuclease and cathepsin D on
Autor:
John F. Thomson, Florence J. Klipfel
Publikováno v:
Biochemical Pharmacology. 3:283-288
In animals that had drunk 50% heavy water until about one-third of their body water was replaced by D 2 O, changes were observed in the tissue levels of several enzymes. The arginase and oxalacetate transaminase activities of rat liver were significa
Autor:
John F. Thomson, Eleanor T. Mikuta
Publikováno v:
Experimental Biology and Medicine. 85:29-32
SummaryTotal-body x-irradiation produces within a few hours a dose-dependent increase in the tryptophan peroxidase-oxidase system of rat liver. The increase does not occur in adrenalectomized rats, and hence cannot be construed as a direct effect of
Autor:
John F. Thomson
Publikováno v:
Archives of Biochemistry and Biophysics. 90:1-6
The initial rate of conversion of fumarate to malate in the presence of crystalline fumarase was decreased when the reaction was carried out in the presence of D2O; the reverse reaction was inhibited to a lesser extent. The maximum rate for the forwa
Autor:
Eleanor M. Moss, John F. Thomson
Publikováno v:
Cancer. 8:789-795
Publikováno v:
The Journal of General Physiology
1. Liver, kidney, brain, skeletal muscle, and cardiac muscle from one newborn and three adult long-snouted dolphins (Stenella plagiodon) were obtained for enzyme studies. 2. All of the dolphin tissues exhibited cytochrome oxidase, succinic dehydrogen
Autor:
John F. Thomson
Publikováno v:
Annual Review of Nuclear Science. 4:377-400