Zobrazeno 1 - 10
of 145
pro vyhledávání: '"John F. Rawls"'
Autor:
Yang Jin, Darby Kozan, Eric D. Young, Monica R. Hensley, Meng-Chieh Shen, Jia Wen, Tabea Moll, Jennifer L. Anderson, Hannah Kozan, John F. Rawls, Steven A. Farber
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 10, Pp 100637- (2024)
Zebrafish are an ideal model organism to study lipid metabolism and to elucidate the molecular underpinnings of human lipid-associated disorders. Unlike murine models, to which various standardized high lipid diets such as a high-cholesterol diet (HC
Externí odkaz:
https://doaj.org/article/159ff70980c24266ae6b70193f1640e1
Autor:
Shiori Naruoka, Souhei Sakata, Shigeru Kawabata, Yasuyuki Hashiguchi, Eriko Daikoku, Shoichi Sakaguchi, Fumiyoshi Okazaki, Kento Yoshikawa, John F. Rawls, Takashi Nakano, Yoshinobu Hirose, Fumihito Ono
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37510- (2024)
In the process of investigating synaptic changes happening to mutants lacking postsynaptic receptors in the neuromuscular junction, we focused on a hitherto uncharacterized zebrafish gene zgc153932 whose expression was increased in the RNAseq and dro
Externí odkaz:
https://doaj.org/article/48649a7e2c4b41a4852a793a3ccdd31e
Autor:
James H. Thierer, Ombretta Foresti, Pradeep Kumar Yadav, Meredith H. Wilson, Tabea O. C. Moll, Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Margaret Morash, Karen L. Mohlke, John F. Rawls, Vivek Malhotra, M. Mahmood Hussain, Steven A. Farber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Vertebrates transport hydrophobic triglycerides through the circulatory system by packaging them within amphipathic particles called Triglyceride-Rich Lipoproteins. Yet, it remains largely unknown how triglycerides are loaded onto these part
Externí odkaz:
https://doaj.org/article/0c842b9c7eca4be6a40b1c67e56efa1a
Autor:
Cecelia Kelly, Jayanth Jawahar, Lauren Davey, Jeffrey I. Everitt, Joseph A. Galanko, Chelsea Anderson, Jonathan E. Avendano, Jessica R. McCann, R. Balfour Sartor, Raphael H. Valdivia, John F. Rawls
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT The inflammatory bowel diseases (IBD) occur in genetically susceptible individuals who mount inappropriate immune responses to their microbiota leading to chronic intestinal inflammation. Whereas IBD clinical presentation is well described,
Externí odkaz:
https://doaj.org/article/9abd9028521d41f8bde75308d6ab2f5a
Autor:
James H. Thierer, Ombretta Foresti, Pradeep Kumar Yadav, Meredith H. Wilson, Tabea O. C. Moll, Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Margaret Morash, Karen L. Mohlke, John F. Rawls, Vivek Malhotra, M. Mahmood Hussain, Steven A. Farber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/1aabdb2bf28d41d2a79b6d4579ae6e87
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Animals rely heavily on their nervous and immune systems to perceive and survive within their environment. Despite the traditional view of the brain as an immunologically privileged organ, these two systems interact with major consequences.
Externí odkaz:
https://doaj.org/article/1fffe43ab261482d952779d3b1312877
Autor:
Jayanth Jawahar, Alexander W. McCumber, Colin R. Lickwar, Caroline R. Amoroso, Sol Gomez de la Torre Canny, Sandi Wong, Margaret Morash, James H. Thierer, Steven A. Farber, Brendan J. M. Bohannan, Karen Guillemin, John F. Rawls
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background The ability of animals and their microbiomes to adapt to starvation and then restore homeostasis after refeeding is fundamental to their continued survival and symbiosis. The intestine is the primary site of nutrient absorption an
Externí odkaz:
https://doaj.org/article/08d486c495ba4c1a9aabba407037981a
Autor:
Chuyi Chen, Yuyang Gu, Julien Philippe, Peiran Zhang, Hunter Bachman, Jinxin Zhang, John Mai, Joseph Rufo, John F. Rawls, Erica E. Davis, Nicholas Katsanis, Tony Jun Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Existing methods of zebrafish phenotyping rely on contact-based processes. Here the authors report on an acoustofluidic-based platform which performs contactless specimen rotation, that results in multispectral images for rapid morphological phenotyp
Externí odkaz:
https://doaj.org/article/26c1153a5c4342ae841c0823cce84d2b
Autor:
Nellie Y. Loh, James E. N. Minchin, Katherine E. Pinnick, Manu Verma, Marijana Todorčević, Nathan Denton, Julia El-Sayed Moustafa, John P. Kemp, Celia L. Gregson, David M. Evans, Matt J. Neville, Kerrin S. Small, Mark I. McCarthy, Anubha Mahajan, John F. Rawls, Fredrik Karpe, Constantinos Christodoulides
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Genetic variants at the RSPO3 locus are associated with waist-to-hip ratio (adjusted for BMI). Here, Loh et al. describe two independent RSPO3 signals that associate with body fat distribution, perform fine-mapping and explore the function of RSPO3 i
Externí odkaz:
https://doaj.org/article/63058441426945e38b49d38d86552953
Autor:
Sarah C. Armstrong, McAllister Windom, Nathan A. Bihlmeyer, Jennifer S. Li, Svati H. Shah, Mary Story, Nancy Zucker, William E. Kraus, Neha Pagidipati, Eric Peterson, Charlene Wong, Manuela Wiedemeier, Lauren Sibley, Samuel I. Berchuck, Peter Merrill, Alexandra Zizzi, Charles Sarria, Holly K. Dressman, John F. Rawls, Asheley C. Skinner
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The prevalence of child and adolescent obesity and severe obesity continues to increase despite decades of policy and research aimed at prevention. Obesity strongly predicts cardiovascular and metabolic disease risk; both begin in
Externí odkaz:
https://doaj.org/article/ee715c5ac71841a8a39d6b7228e72e94