Zobrazeno 1 - 10
of 122
pro vyhledávání: '"John F. Oram"'
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 7, Pp 1719-1728 (2010)
Accumulation of cholesterol in arterial macrophages may contribute to diabetes-accelerated atherosclerotic cardiovascular disease. The ATP-binding cassette transporter ABCA1 is a cardioprotective membrane protein that mediates cholesterol export from
Externí odkaz:
https://doaj.org/article/6208e2359dda4783a7c0ccc79a081fca
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 7, Pp 1849-1858 (2010)
A key cardioprotective effect of high-density lipoprotein involves the interaction of its major protein, apolipoprotein A-I (apoA-I) with ATP-binding cassette transporter A1 (ABCA1), a macrophage cholesterol exporter. ApoA-I is thought to remove chol
Externí odkaz:
https://doaj.org/article/23122002f6a84e608f60051d12b3b45d
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 285-292 (2009)
ABCA1 exports cholesterol and phospholipids from cells by a multistep pathway that involves forming cell surface lipid domains, solubilizing these lipids by apolipoproteins, binding of apolipoproteins to ABCA1, and activating signaling processes. Her
Externí odkaz:
https://doaj.org/article/0ff7875140ba447f93499be513c484c8
Autor:
Sandhya Sankaranarayanan, John F. Oram, Bela F. Asztalos, Ashley M. Vaughan, Sissel Lund-Katz, Maria Pia Adorni, Michael C. Phillips, George H. Rothblat
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 275-284 (2009)
Among the known mechanisms of reverse cholesterol transport (RCT), ATP binding cassette transporter G1 (ABCG1)-mediated free cholesterol (FC) transport is the most recent and least studied. Here, we have characterized the efficiencies of different ac
Externí odkaz:
https://doaj.org/article/54cfcbcf4e7544b4823a77447af6b211
Autor:
Wang Yutong, John F. Oram
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 5, Pp 1062-1068 (2007)
Abnormal HDL metabolism among patients with diabetes and insulin resistance may contribute to their increased risk of atherosclerosis. ABCA1 mediates the transport of cholesterol and phospholipids from cells to HDL apolipoproteins and thus modulates
Externí odkaz:
https://doaj.org/article/45217280da22470698c94cd4163f5f86
Autor:
Ashley M. Vaughan, John F. Oram
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 11, Pp 2433-2443 (2006)
Recent developments in lipid metabolism have shown the importance of ATP binding cassette transporters (ABCs) in controlling cellular and total body lipid homeostasis. ABCA1 mediates the transport of cholesterol and phospholipids from cells to lipid-
Externí odkaz:
https://doaj.org/article/32a54334f8814a0c99bbfda6d3d7e5dd
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 107-114 (2006)
ABCA1 mediates the transport of cellular cholesterol and phospholipids to HDL apolipoproteins. Apolipoprotein A-I (apoA-I) interactions with ABCA1-expressing cells elicit several responses, including removing cellular lipids, stabilizing ABCA1 protei
Externí odkaz:
https://doaj.org/article/4864367734084987815b2a10b6a60738
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 3, Pp 389-403 (2005)
In humans, a chronically increased circulating level of C-reactive protein (CRP), a positive acute-phase reactant, is an independent risk factor for cardiovascular disease. This observation has led to considerable interest in the role of inflammatory
Externí odkaz:
https://doaj.org/article/5dd97a1ce06e4b328486fcc33467a55a
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 5, Pp 972-980 (2004)
Abnormal HDL metabolism among patients with diabetes and insulin resistance may contribute to their increased risk of atherosclerosis. ATP binding cassette transporter A1 (ABCA1) mediates the transport of cholesterol and phospholipids from cells to H
Externí odkaz:
https://doaj.org/article/a84710fd2999452797e9bddf91dfcda8
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 8, Pp 1552-1558 (2003)
HDL subspecies Lp(A-I) and Lp(A-I,A-II) have different anti-atherogenic potentials. To determine the role of lipoprotein lipase (LPL) and hepatic lipase (HL) in regulating these particles, we measured these enzyme activities in 28 healthy subjects wi
Externí odkaz:
https://doaj.org/article/de9988d67e3e4da8b65da98b9df8927a